FGF-23 and secondary hyperparathyroidism in chronic kidney disease (Q38123396)

29 August 2017

FGF-23 and secondary hyperparathyroidism in chronic kidney disease (English)

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secondary hyperparathyroidism

29 August 2017

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Justin Silver

1

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29 August 2017

Tally Naveh-Many

series ordinal

2

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29 August 2017

language of work or name

English

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publication date

23 July 2013

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Nature Reviews Nephrology

29 August 2017

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29 August 2017

9

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29 August 2017

641-649

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29 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nrneph.2013.147

29 August 2017

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cites work

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Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing

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Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation

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Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis

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Phosphorus binders and survival on hemodialysis

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Fibroblast growth factor-23 and early decrements in kidney function: the Heart and Soul Study

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Mechanisms of secondary hyperparathyroidism

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The role of FGF23 in CKD--with or without Klotho.

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Update on fibroblast growth factor 23 in chronic kidney disease

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Role of FGF23 in vitamin D and phosphate metabolism: implications in chronic kidney disease

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FGF23 and PTH--double agents at the heart of CKD.

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Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23.

21 January 2018

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On the pathogenesis of hyperparathyroidism in chronic experimental renal insufficiency in the dog

21 January 2018

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The role of phosphorus restriction in the prevention of secondary hyperparathyroidism in chronic renal disease

21 January 2018

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Parathyroid hormone gene expression in hypophosphatemic rats

21 January 2018

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Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro

21 January 2018

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Hyperphosphatemia-induced nanocrystals upregulate the expression of bone morphogenetic protein-2 and osteopontin genes in mouse smooth muscle cells in vitro

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Dietary and serum phosphorus regulate fibroblast growth factor 23 expression and 1,25-dihydroxyvitamin D metabolism in mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the receptor in parathyroid physiology

21 January 2018

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Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men.

21 January 2018

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Fibroblast growth factor 23, cardiovascular disease risk factors, and phosphorus intake in the health professionals follow-up study

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Effect of acute changes of serum phosphate on fibroblast growth factor (FGF)23 levels in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Postprandial mineral metabolism and secondary hyperparathyroidism in early CKD

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Early control of PTH and FGF23 in normophosphatemic CKD patients: a new target in CKD-MBD therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Pilot study of dietary phosphorus restriction and phosphorus binders to target fibroblast growth factor 23 in patients with chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

FGF-23 is elevated by chronic hyperphosphatemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

A novel mutation in fibroblast growth factor 23 gene as a cause of tumoral calcinosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Fibroblast growth factor (FGF)-23 in patients with primary hyperparathyroidism

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Fibroblast growth factor 23, parathyroid hormone, and 1alpha,25-dihydroxyvitamin D in surgically treated primary hyperparathyroidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

FGF-23/Klotho signaling is not essential for the phosphaturic and anabolic functions of PTH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Reduced plasma pyrophosphate levels in hemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Bone pyrophosphate in uremia and its association with extraosseous calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Entpd5 is essential for skeletal mineralization and regulates phosphate homeostasis in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Loss-of-function ENPP1 mutations cause both generalized arterial calcification of infancy and autosomal-recessive hypophosphatemic rickets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Endocrine functions of bone in mineral metabolism regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Regulation of bone-renal mineral and energy metabolism: the PHEX, FGF23, DMP1, MEPE ASARM pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Regulation and function of the FGF23/klotho endocrine pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF-23 signaling and regulating FGF-23 expression in bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Osteocyte messages from a bony tomb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. The HYP Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

FGF23 is a putative marker for bone healing and regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Human PTH gene regulation in vivo using transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

FGF23 fails to inhibit uremic parathyroid glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

FGF23-parathyroid interaction: implications in chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Increased parathyroid expression of klotho in uremic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Regulation of plasma fibroblast growth factor 23 by calcium in primary hyperparathyroidism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Hypophosphatemia with elevations in serum fibroblast growth factor 23 in a child with Jansen's metaphyseal chondrodysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Effects of cinacalcet and concurrent low-dose vitamin D on FGF23 levels in ESRD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Fibroblast growth factor 23 is a counter-regulatory phosphaturic hormone for vitamin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Circulating FGF-23 is regulated by 1alpha,25-dihydroxyvitamin D3 and phosphorus in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Serum leptin, parathyroid hormone, 1,25-dihydroxyvitamin D, fibroblast growth factor 23, bone alkaline phosphatase, and sclerostin relationships in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Leptin stimulates fibroblast growth factor 23 expression in bone and suppresses renal 1alpha,25-dihydroxyvitamin D3 synthesis in leptin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

1,25-dihydroxyvitamin D(3) regulation of fibroblast growth factor-23 expression in bone cells: evidence for primary and secondary mechanisms modulated by leptin and interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

CaSR-mediated interactions between calcium and magnesium homeostasis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Calcium deficiency reduces circulating levels of FGF23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

alpha-Klotho as a regulator of calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

A translocation causing increased alpha-klotho level results in hypophosphatemic rickets and hyperparathyroidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Circulating αKlotho influences phosphate handling by controlling FGF23 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

αKlotho: FGF23 coreceptor and FGF23-regulating hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Metabolic acidosis increases fibroblast growth factor 23 in neonatal mouse bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Indirect regulation of PTH by estrogens may require FGF23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Serological cardiovascular and mortality risk predictors in dialysis patients receiving sevelamer: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Renal phosphate wasting in fibrous dysplasia of bone is part of a generalized renal tubular dysfunction similar to that seen in tumor-induced osteomalacia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Genetic dissection of phosphate- and vitamin D-mediated regulation of circulating Fgf23 concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

FGF23 and disorders of phosphate homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Mechanism of FGF23 processing in fibrous dysplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

FGF23 induces left ventricular hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Cinacalcet treatment and serum FGF23 levels in haemodialysis patients with secondary hyperparathyroidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Parabiosis suggests a humoral factor is involved in X-linked hypophosphatemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Direct effect of phosphorus on PTH secretion from whole rat parathyroid glands in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Acute effect of oral phosphate loading on serum fibroblast growth factor 23 levels in healthy men

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Regulation of fibroblast growth factor-23 in chronic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Secreted Klotho and FGF23 in chronic kidney disease Stage 1 to 5: a sequence suggested from a cross-sectional study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Lanthanum carbonate reduces FGF23 in chronic kidney disease Stage 3 patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Fibroblast growth factor-23 (FGF23) in patients with transient hypoparathyroidism: its important role in serum phosphate regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Correction: Altered Bone Development and an Increase in FGF-23 Expression in Enpp1−/− Mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Changes in fibroblast growth factor 23 during treatment of secondary hyperparathyroidism with alfacalcidol or paricalcitol

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

Effect of intravenous saccharated ferric oxide on serum FGF23 and mineral metabolism in hemodialysis patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2013.147

The parathyroid is a target organ for FGF23 in rats

31 March 2020

1 reference

12 December 2020

Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia

1 reference

12 December 2020

Altered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice

1 reference

12 December 2020

A direct effect in vitro of phosphate on PTH release from bovine parathyroid tissue slices but not from dispersed parathyroid cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2013.147

1 reference

Dimensions Publication ID

29 August 2017

0 references

1 reference