The p53 miRNA interactome and its potential role in the cancer clinic (Q38124951)

29 August 2017

The p53 miRNA interactome and its potential role in the cancer clinic (English)

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29 August 2017

Jonathan Krell

1

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29 August 2017

Adam E Frampton

2

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29 August 2017

Teresa Colombo

3

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29 August 2017

Tamara M H Gall

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29 August 2017

Alex De Giorgio

5

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29 August 2017

Victoria Harding

6

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29 August 2017

Justin Stebbing

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29 August 2017

Leandro Castellano

8

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29 August 2017

1 August 2013

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29 August 2017

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29 August 2017

417-428

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p53 opens the mitochondrial permeability transition pore to trigger necrosis

29 August 2017

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The cellular response to p53: the decision between life and death

21 January 2018

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p53, the cellular gatekeeper for growth and division

21 January 2018

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

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Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

21 January 2018

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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

21 January 2018

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A microRNA component of the p53 tumour suppressor network

21 January 2018

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p53 represses c-Myc through induction of the tumor suppressor miR-145

21 January 2018

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Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

21 January 2018

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MicroRNAs in the p53 network: micromanagement of tumour suppression

21 January 2018

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Modulation of microRNA processing by p53

21 January 2018

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Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

21 January 2018

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Negative regulation of tumor suppressor p53 by microRNA miR-504

21 January 2018

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MicroRNA-125b is a novel negative regulator of p53.

21 January 2018

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miR-34a repression of SIRT1 regulates apoptosis

21 January 2018

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MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells

21 January 2018

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BM-ca is a newly defined type I/II anti-CD20 monoclonal antibody with unique biological properties.

21 January 2018

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Negative regulation of the tumor suppressor p53 gene by microRNAs.

21 January 2018

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MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth

21 January 2018

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Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

21 January 2018

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Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

21 January 2018

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miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

21 January 2018

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Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis

21 January 2018

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Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress-induced ligand of the natural killer cell receptor NKG2D.

21 January 2018

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p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

21 January 2018

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Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer

21 January 2018

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P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

21 January 2018

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Role of microRNA-182 in posterior uveal melanoma: regulation of tumor development through MITF, BCL2 and cyclin D2

21 January 2018

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Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development

21 January 2018

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

21 January 2018

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p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.

21 January 2018

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Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia

21 January 2018

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miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner

21 January 2018

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The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia

21 January 2018

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MiR-15a and MiR-16 control Bmi-1 expression in ovarian cancer

21 January 2018

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

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The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

21 January 2018

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The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

21 January 2018

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p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins

21 January 2018

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MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells

21 January 2018

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Cellular stress induced alterations in microRNA let-7a and let-7b expression are dependent on p53

21 January 2018

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p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancers

21 January 2018

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MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma

21 January 2018

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Tumor suppressor p53 meets microRNAs

21 January 2018

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The tumor suppressors p53, p63, and p73 are regulators of microRNA processing complex

21 January 2018

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Altered expression of the miRNA processing endoribonuclease Dicer has prognostic significance in human cancers

21 January 2018

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Dicer1 functions as a haploinsufficient tumor suppressor

21 January 2018

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Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity

21 January 2018

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Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs

21 January 2018

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miR-33-mediated downregulation of p53 controls hematopoietic stem cell self-renewal

21 January 2018

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miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma.

21 January 2018

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MicroRNA-1285 inhibits the expression of p53 by directly targeting its 3' untranslated region

21 January 2018

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MiR-34, SIRT1 and p53: the feedback loop

21 January 2018

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miR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress

21 January 2018

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An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs.

21 January 2018

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ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression

21 January 2018

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Network motifs: simple building blocks of complex networks

21 January 2018

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Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation

21 January 2018

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MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression.

21 January 2018

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An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells

21 January 2018

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MiR-125b is critical for the suppression of human U251 glioma stem cell proliferation

21 January 2018

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Evolution under canalization and the dual roles of microRNAs: a hypothesis

21 January 2018

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Circuit topology and the evolution of robustness in two-gene circadian oscillators

21 January 2018

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Intact p53-dependent responses in miR-34-deficient mice.

21 January 2018

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miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma.

21 January 2018

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21 January 2018

Human MicroRNA targets

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

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Human microRNAs target a functionally distinct population of genes with AT-rich 3' UTRs

21 January 2018

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MicroRNAs in the cancer clinic

21 January 2018

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Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice

21 January 2018

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A p53-inducible microRNA-34a downregulates Ras signaling by targeting IMPDH.

21 January 2018

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A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition.

21 January 2018

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p53 and microRNA-34 are suppressors of canonical Wnt signaling.

21 January 2018

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MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1.

21 January 2018

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MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells

21 January 2018

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miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes.

21 January 2018

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miR-122 regulates p53/Akt signalling and the chemotherapy-induced apoptosis in cutaneous T-cell lymphoma

21 January 2018

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MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer

21 January 2018

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MicroRNA-182 downregulates metastasis suppressor 1 and contributes to metastasis of hepatocellular carcinoma

21 January 2018

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Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215.

21 January 2018

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miR-192 Regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit

21 January 2018

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Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

21 January 2018

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Regulation of vascular endothelial growth factor signaling by miR-200b.

21 January 2018

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Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer.

21 January 2018

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miR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress.

21 January 2018

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p53-Dependent induction of PVT1 and miR-1204.

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/EPI.13.41

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29 August 2017

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