Immune regulatory functions of DOCK family proteins in health and disease (Q38126300)

29 August 2017

Immune regulatory functions of DOCK family proteins in health and disease (English)

1 reference

29 August 2017

3

1 reference

PubMed ID

23911989

29 August 2017

Mutsuko Kukimoto-Niino

object named as

Mutsuko Kukimoto-Niino

series ordinal

2

0 references

Akihiko Nishikimi

object named as

Akihiko Nishikimi

series ordinal

1

0 references

Yoshinori Fukui

object named as

Yoshinori Fukui

series ordinal

4

0 references

language of work or name

English

0 references

publication date

2 August 2013

1 reference

Experimental Cell Research

29 August 2017

1 reference

29 August 2017

319

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29 August 2017

15

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29 August 2017

2343-2349

1 reference

Regulation of innate immunity by Rho GTPases

29 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Rho family GTPases and their regulators in lymphocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

The CDM protein DOCK2 in lymphocyte migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (DOCK) Nucleotide Exchange Factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

DOCK2 regulates Rac activation and cytoskeletal reorganization through interaction with ELMO1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Mouse and human dendritic cell subtypes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Differential requirement for DOCK2 in migration of plasmacytoid dendritic cells versus myeloid dendritic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Pathogen recognition and innate immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

IRF-7 is the master regulator of type-I interferon-dependent immune responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Combined immunodeficiency associated with DOCK8 mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Defective actin accumulation impairs human natural killer cell function in patients with dedicator of cytokinesis 8 deficiency.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

DOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memory

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Rapid leukocyte migration by integrin-independent flowing and squeezing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2013.07.024

10.1016/J.YEXCR.2013.07.024

7 January 2021

Identifiers

DOI

1 reference

29 August 2017

1 reference

PubMed ID

23911989