Macro view of microRNA function in osteoarthritis (Q38034389)

27 August 2017

Macro view of microRNA function in osteoarthritis (English)

1 reference

27 August 2017

0 references

1 reference

Shigeru Miyaki

1

1 reference

27 August 2017

Hiroshi Asahara

series ordinal

2

1 reference

27 August 2017

language of work or name

English

0 references

publication date

14 August 2012

1 reference

Nature Reviews Rheumatology

27 August 2017

1 reference

27 August 2017

8

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27 August 2017

543-552

1 reference

27 August 2017

9

1 reference

https://scigraph.springernature.com/pub.10.1038/nrrheum.2012.128

27 August 2017

0 references

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MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis

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HIF-2α as a possible therapeutic target of osteoarthritis

6 September 2017

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MicroRNA and aging: a novel modulator in regulating the aging network

6 September 2017

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Serum microRNAs as powerful cancer biomarkers

6 September 2017

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Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

6 September 2017

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New developments in osteoarthritis. Posttraumatic osteoarthritis: pathogenesis and pharmacological treatment options

6 September 2017

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Type II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes.

6 September 2017

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Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways

6 September 2017

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Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis

6 September 2017

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MicroRNA-140 plays dual roles in both cartilage development and homeostasis

6 September 2017

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microRNA as a new immune-regulatory agent in breast milk

6 September 2017

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New molecular targets for the treatment of osteoarthritis

6 September 2017

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MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes.

6 September 2017

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Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes

6 September 2017

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Epigenetic Control of MicroRNA Expression and Aging

6 September 2017

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MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses

6 September 2017

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Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis

6 September 2017

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siRNA delivery using peptide transduction domains

6 September 2017

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Cartilage homeostasis in health and rheumatic diseases

6 September 2017

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OA clinical trials: current targets and trials for OA. Choosing molecular targets: what have we learned and where we are headed?

6 September 2017

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Expression of MicroRNA-146a in osteoarthritis cartilage

6 September 2017

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6 September 2017

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Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks

6 September 2017

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Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients

6 September 2017

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Circulating microRNAs as stable blood-based markers for cancer detection

6 September 2017

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Expression of microRNA-146 in rheumatoid arthritis synovial tissue

6 September 2017

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Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

6 September 2017

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MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis

6 September 2017

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Dicer-dependent pathways regulate chondrocyte proliferation and differentiation

6 September 2017

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Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Molecular network of cartilage homeostasis and osteoarthritis

6 September 2017

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Characterization of microRNA expression profiles in normal human tissues

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Characterization of the human ADAMTS-5 (aggrecanase-2) gene promoter

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

MicroRNA signatures in human cancers

6 September 2017

1 reference

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NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

The widespread impact of mammalian MicroRNAs on mRNA repression and evolution

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

MicroRNA expression in zebrafish embryonic development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Processing of primary microRNAs by the Microprocessor complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

The Microprocessor complex mediates the genesis of microRNAs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

MicroRNAs: genomics, biogenesis, mechanism, and function

6 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

6 September 2017

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Dicer is essential for mouse development

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

The nuclear RNase III Drosha initiates microRNA processing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

MicroRNA-140 and the silencing of osteoarthritis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded MicroRNA-15a.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Profiling microRNA expression in bovine articular cartilage and implications for mechanotransduction

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-alpha and MMP13.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572197

Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP

31 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Myogenic factors that regulate expression of muscle-specific microRNAs

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Non-coding RNAs in human disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

A microRNA expression signature of human solid tumors defines cancer gene targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Analysis of microRNA knockouts in mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Assessment of the profiling microRNA expression of differentiated and dedifferentiated human adult articular chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Sox9 is upstream of microRNA-140 in cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

The expression and function of microRNAs in chondrogenesis and osteoarthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

SIRT1 regulation of apoptosis of human chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

miR-22 represses cancer progression by inducing cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

MicroRNAs in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Osteochondral alterations in osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

MicroRNA-223 is a key factor in osteoclast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Impaired micro-RNA pathways diminish osteoclast differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

miR-210 promotes osteoblastic differentiation through inhibition of AcvR1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

mRNA expression profiling reveals conserved and non-conserved miR-140 targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Potential involvement of SIRT1 in the pathogenesis of osteoarthritis through the modulation of chondrocyte gene expressions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Silencing microRNA-34a inhibits chondrocyte apoptosis in a rat osteoarthritis model in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Changes in microRNA expression in peripheral mononuclear cells according to the progression of osteoarthritis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.128

31 March 2020

Identifiers

DOI

10.1038/NRRHEUM.2012.128

1 reference

Dimensions Publication ID

27 August 2017

0 references

1 reference

27 August 2017

1 reference