Innate antiviral immune signaling, viral evasion and modulation by HIV-1. (Q38170229)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326250%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Innate antiviral immune signaling, viral evasion and modulation by HIV-1 (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326250%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326250%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Michael Gale

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326250%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Arjun Rustagi

series ordinal

1

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30 August 2017

language of work or name

English

0 references

publication date

8 December 2013

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326250%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular Biology

2 March 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326250%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

426

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326250%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

1161-1177

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24326250%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

issue

6

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Triggering the interferon antiviral response through an IKK-related pathway

2 March 2020

cites work

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12 December 2020

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

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12 December 2020

A diverse range of gene products are effectors of the type I interferon antiviral response

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12 December 2020

The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein

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12 December 2020

The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation

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12 December 2020

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

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12 December 2020

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

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12 December 2020

Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences

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12 December 2020

SAMHD1 is a nucleic-acid binding protein that is mislocalized due to aicardi-goutières syndrome-associated mutations

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12 December 2020

Absence of the type I IFN system in EC cells: transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated

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12 December 2020

Epstein-Barr virus BRLF1 inhibits transcription of IRF3 and IRF7 and suppresses induction of interferon-beta

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12 December 2020

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

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12 December 2020

IRF-1 is required for full NF-kappaB transcriptional activity at the human immunodeficiency virus type 1 long terminal repeat enhancer

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12 December 2020

Innate sensing of HIV-1 assembly by Tetherin induces NFκB-dependent proinflammatory responses.

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12 December 2020

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

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12 December 2020

Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation

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12 December 2020

IFI16 is an innate immune sensor for intracellular DNA

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12 December 2020

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling

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12 December 2020

Immune evasion and counteraction of restriction factors by HIV-1 and other primate lentiviruses

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12 December 2020

ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic viruses

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12 December 2020

Structural mechanism of cytosolic DNA sensing by cGAS

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12 December 2020

Multiple regulatory domains control IRF-7 activity in response to virus infection

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12 December 2020

The IFITM proteins inhibit HIV-1 infection

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12 December 2020

Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps

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12 December 2020

Uridine composition of the poly-U/UC tract of HCV RNA defines non-self recognition by RIG-I.

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12 December 2020

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12 December 2020

Viperin: a multifunctional, interferon-inducible protein that regulates virus replication

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12 December 2020

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

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12 December 2020

Innate sensing of HIV-infected cells

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12 December 2020

Vpu-deficient HIV strains stimulate innate immune signaling responses in target cells

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12 December 2020

New, intensive trials planned on heels of Mississippi HIV 'cure'

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12 December 2020

RETRACTED: The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling

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12 December 2020

Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution

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12 December 2020

Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions

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12 December 2020

The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif

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12 December 2020

Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway

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12 December 2020

Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription

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12 December 2020

Cytosolic sensing of viruses

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12 December 2020

Regulation of adaptive immunity by the innate immune system

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12 December 2020

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

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12 December 2020

Viral induction of the zinc finger antiviral protein is IRF3-dependent but NF-kappaB-independent

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12 December 2020

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

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12 December 2020

The structural biology of Toll-like receptors

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12 December 2020

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

1 reference

12 December 2020

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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12 December 2020

The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction

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12 December 2020

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

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12 December 2020

DENV inhibits type I IFN production in infected cells by cleaving human STING

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12 December 2020

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

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12 December 2020

The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3

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12 December 2020

Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

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12 December 2020

HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators

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12 December 2020

Autophagy-dependent viral recognition by plasmacytoid dendritic cells

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12 December 2020

Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.

1 reference

12 December 2020

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.

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12 December 2020

Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach

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12 December 2020

Innate immune recognition of HIV-1

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12 December 2020

Inhibition of interferon regulatory factor 7 (IRF7)-mediated interferon signal transduction by the Kaposi's sarcoma-associated herpesvirus viral IRF homolog vIRF3.

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12 December 2020

Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein

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12 December 2020

HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation

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12 December 2020

Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers

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12 December 2020

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

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12 December 2020

Activation of double-stranded RNA-activated protein kinase (PKR) by interferon-stimulated gene 15 (ISG15) modification down-regulates protein translation

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12 December 2020

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING

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12 December 2020

HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production

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12 December 2020

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

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12 December 2020

Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation

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12 December 2020

Viral interferon regulatory factors

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12 December 2020

The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry

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12 December 2020

The IRF-3/Bax-mediated apoptotic pathway, activated by viral cytoplasmic RNA and DNA, inhibits virus replication

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12 December 2020

Vpu mediates depletion of interferon regulatory factor 3 during HIV infection by a lysosome-dependent mechanism

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12 December 2020

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

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12 December 2020

Viral targeting of the interferon-{beta}-inducing Traf family member-associated NF-{kappa}B activator (TANK)-binding kinase-1.

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12 December 2020

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

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12 December 2020

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

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12 December 2020

Inhibition of interferon signaling by the Kaposi's sarcoma-associated herpesvirus full-length viral interferon regulatory factor 2 protein.

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12 December 2020

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses

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12 December 2020

TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response

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12 December 2020

The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.

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12 December 2020

Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch

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12 December 2020

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

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12 December 2020

Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3

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12 December 2020

HIV-1 infection of human macrophages directly induces viperin which inhibits viral production.

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12 December 2020

Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells.

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12 December 2020

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

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12 December 2020

The immune response during acute HIV-1 infection: clues for vaccine development

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12 December 2020

An Atomic Model of the Interferon-β Enhanceosome

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12 December 2020

Modulation of human immunodeficiency virus 1 replication by interferon regulatory factors

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12 December 2020

Human immunodeficiency virus type 1 mediates global disruption of innate antiviral signaling and immune defenses within infected cells

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12 December 2020

The NPro Product of Bovine Viral Diarrhea Virus Inhibits DNA Binding by Interferon Regulatory Factor 3 and Targets It for Proteasomal Degradation

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12 December 2020

Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms

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12 December 2020

Rhesus cytomegalovirus particles prevent activation of interferon regulatory factor 3.

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12 December 2020

Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue

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12 December 2020

Regulation of type I interferon gene expression by interferon regulatory factor-3.

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12 December 2020

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

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12 December 2020

Human bocavirus NP1 inhibits IFN-β production by blocking association of IFN regulatory factor 3 with IFNB promoter

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12 December 2020

Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag

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12 December 2020

Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7.

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12 December 2020

IFN-α induces APOBEC3G, F, and A in immature dendritic cells and limits HIV-1 spread to CD4+ T cells.

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12 December 2020

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

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12 December 2020

Cutting edge: Ku70 is a novel cytosolic DNA sensor that induces type III rather than type I IFN.

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12 December 2020

A new pathway of translational regulation mediated by eukaryotic initiation factor 3

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12 December 2020

Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.

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12 December 2020

Inhibition of transcription of the beta interferon gene by the human herpesvirus 6 immediate-early 1 protein

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12 December 2020

RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity.

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12 December 2020

Induction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti-HIV-1 activity

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12 December 2020

Approaching the asymptote? Evolution and revolution in immunology

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12 December 2020

Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity

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12 December 2020

Recognition of viruses by cytoplasmic sensors

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12 December 2020

A weak signal for strong responses: interferon-alpha/beta revisited

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12 December 2020

Identification of a novel in vivo virus-targeted phosphorylation site in interferon regulatory factor-3 (IRF3)

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12 December 2020

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

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12 December 2020

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

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12 December 2020

Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth

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12 December 2020

The mitochondrial targeting chaperone 14-3-3ε regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity.

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12 December 2020

Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes

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12 December 2020

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

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12 December 2020

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

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12 December 2020

The linker of the interferon response factor 3 transcription factor is not unfolded

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12 December 2020

IRF-3-dependent and augmented target genes during viral infection.

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12 December 2020

Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism

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12 December 2020

Dendritic cell dysregulation during HIV-1 infection

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12 December 2020

How the noninflammasome NLRs function in the innate immune system

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12 December 2020

Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage

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12 December 2020

Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors

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12 December 2020

Pathogen recognition and innate immunity

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12 December 2020

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

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12 December 2020

Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells

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12 December 2020

Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus

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12 December 2020

Varicella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3

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12 December 2020

Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study

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12 December 2020

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

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12 December 2020

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

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12 December 2020

The human immunodeficiency virus type 1 Nef and Vpu proteins downregulate the natural killer cell-activating ligand PVR.

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12 December 2020

Epstein-Barr virus BGLF4 kinase suppresses the interferon regulatory factor 3 signaling pathway

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12 December 2020

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.

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12 December 2020

NLR functions beyond pathogen recognition

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12 December 2020

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

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12 December 2020

Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes

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12 December 2020

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

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12 December 2020

Inhibition of retroviral RNA production by ZAP, a CCCH-type zinc finger protein

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12 December 2020

The specific and essential role of MAVS in antiviral innate immune responses

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12 December 2020

Recent advances in understanding viral evasion of type I interferon

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12 December 2020

Antibody neutralization and escape by HIV-1

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12 December 2020

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

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12 December 2020

IFITM proteins restrict viral membrane hemifusion

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12 December 2020

Defining emerging roles for NF-κB in antivirus responses: revisiting the interferon-β enhanceosome paradigm

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12 December 2020

Innate receptors for adaptive immunity.

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12 December 2020

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

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12 December 2020

Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA.

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12 December 2020

Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction

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12 December 2020

Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation

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12 December 2020

Glycerol monolaurate prevents mucosal SIV transmission

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12 December 2020

Degranulation of natural killer cells following interaction with HIV-1-infected cells is hindered by downmodulation of NTB-A by Vpu.

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12 December 2020

Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling

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12 December 2020

Type I interferons in host defense

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12 December 2020

Targeting early infection to prevent HIV-1 mucosal transmission.

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12 December 2020

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

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12 December 2020

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

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12 December 2020

Type 1 interferons and antiviral CD8 T-cell responses

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12 December 2020

HIV-1 Vpu affects the anterograde transport and the glycosylation pattern of NTB-A.

1 reference

12 December 2020

The KSHV immediate-early transcription factor RTA encodes ubiquitin E3 ligase activity that targets IRF7 for proteosome-mediated degradation

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12 December 2020

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

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12 December 2020

STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

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12 December 2020

The TRIM family protein KAP1 inhibits HIV-1 integration.

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12 December 2020

Interferon-induced exonuclease ISG20 exhibits an antiviral activity against human immunodeficiency virus type 1.

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12 December 2020

Tetherin inhibits HIV-1 release by directly tethering virions to cells

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12 December 2020

Role of interferon regulatory factor 3-mediated apoptosis in the establishment and maintenance of persistent infection by Sendai virus

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12 December 2020

Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11

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12 December 2020

Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein

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12 December 2020

HIV-1 Vpu does not degrade interferon regulatory factor 3.

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12 December 2020

Vpu binds directly to tetherin and displaces it from nascent virions

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12 December 2020

IRF-7 is the master regulator of type-I interferon-dependent immune responses

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12 December 2020

RIG-I-mediated antiviral signaling is inhibited in HIV-1 infection by a protease-mediated sequestration of RIG-I.

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12 December 2020

Early events in sexual transmission of HIV and SIV and opportunities for interventions

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12 December 2020

Modulation of T-cell function by type I interferon

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12 December 2020

Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction

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12 December 2020

Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection.

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12 December 2020

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

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12 December 2020

Kinetic mechanism for viral dsRNA length discrimination by MDA5 filaments

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12 December 2020

Immune signaling by RIG-I-like receptors

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12 December 2020

Virus infection triggers SUMOylation of IRF3 and IRF7, leading to the negative regulation of type I interferon gene expression

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12 December 2020

The interferon stimulated gene 54 promotes apoptosis

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12 December 2020

Trex1 prevents cell-intrinsic initiation of autoimmunity

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12 December 2020

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

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12 December 2020

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway

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12 December 2020

Innate immune recognition of viral infection

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12 December 2020

The RIG-I-like receptor LGP2 controls CD8(+) T cell survival and fitness

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12 December 2020

Acute HIV-1 Infection

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12 December 2020

Approaching the asymptote: 20 years later

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12 December 2020

STING is a direct innate immune sensor of cyclic di-GMP

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12 December 2020

Small self-RNA generated by RNase L amplifies antiviral innate immunity

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12 December 2020

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

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12 December 2020

Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3

1 reference

12 December 2020

The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response

1 reference

12 December 2020

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

1 reference

12 December 2020

Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA

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12 December 2020

TRIM family proteins and their emerging roles in innate immunity

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12 December 2020

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

1 reference

12 December 2020

Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection

1 reference

12 December 2020

The HIV-1 env protein: a coat of many colors

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12 December 2020

The NS5 Protein of the Virulent West Nile Virus NY99 Strain Is a Potent Antagonist of Type I Interferon-Mediated JAK-STAT Signaling

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12 December 2020

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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12 December 2020

A novel mechanism for the inhibition of interferon regulatory factor-3-dependent gene expression by human respiratory syncytial virus NS1 protein

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12 December 2020

Viral regulation and evasion of the host response.

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12 December 2020