Role of pHi, and proton transporters in oncogene-driven neoplastic transformation (Q38184984)

30 August 2017

Role of pHi, and proton transporters in oncogene-driven neoplastic transformation (English)

1 reference

30 August 2017

Maria Raffaella Greco

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24493748%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

language of work or name

English

0 references

publication date

3 February 2014

1 reference

Philosophical Transactions of the Royal Society B

30 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24493748%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

369

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24493748%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

issue

1638

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24493748%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

20130100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24493748%20AND%20SRC:MED&resulttype=core&format=json

Considering protonation as a posttranslational modification regulating protein structure and function

3 June 2020

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1 reference

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The origin of membrane bioenergetics

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Inside out: targeting NHE1 as an intracellular and extracellular regulator of cancer progression

6 September 2017

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MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors

6 September 2017

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Na+-H+ exchanger, pH regulation and cancer.

6 September 2017

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Perspectives on: SGP symposium on mitochondrial physiology and medicine: the renaissance of mitochondrial pH.

6 September 2017

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6 September 2017

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Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy.

6 September 2017

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NHE-1: a promising target for novel anti-cancer therapeutics

6 September 2017

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Recent developments in targeting carbonic anhydrase IX for cancer therapeutics

6 September 2017

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Hypoxia-induced invadopodia formation involves activation of NHE-1 by the p90 ribosomal S6 kinase (p90RSK).

6 September 2017

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Is the multifunctional Na(+)/H(+) exchanger isoform 1 a potential therapeutic target in cancer?

6 September 2017

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Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review

6 September 2017

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Anti-tumour/metastasis effects of the potassium-sparing diuretic amiloride: an orally active anti-cancer drug waiting for its call-of-duty?

6 September 2017

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In vivo pH in metabolic-defective Ras-transformed fibroblast tumors: key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH.

6 September 2017

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The spatial organization of proton and lactate transport in a rat brain tumor

6 September 2017

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Imaging pH and metastasis

6 September 2017

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Hallmarks of Cancer: The Next Generation

6 September 2017

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pH control mechanisms of tumor survival and growth

6 September 2017

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Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA

6 September 2017

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Tumour–stromal interactions in acid-mediated invasion: A mathematical model

6 September 2017

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Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer

6 September 2017

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The sodium-hydrogen exchanger NHE1 is an Akt substrate necessary for actin filament reorganization by growth factors

6 September 2017

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Proton transport inhibitors as potentially selective anticancer drugs.

6 September 2017

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Molecular basis of metastasis.

6 September 2017

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Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

6 September 2017

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Retracted: HPV16 E7-Dependent Transformation Activates NHE1 through a PKA-RhoA-Iinduced Inhibition of p38alpha

6 September 2017

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Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles

6 September 2017

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Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

6 September 2017

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Beyond ion translocation: structural functions of the sodium-hydrogen exchanger isoform-1

6 September 2017

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The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.

6 September 2017

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Hypoxia signalling in cancer and approaches to enforce tumour regression

6 September 2017

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The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.

6 September 2017

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The role of pH dynamics and the Na+/H+ antiporter in the etiopathogenesis and treatment of cancer. Two faces of the same coin--one single nature

6 September 2017

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Chronic hypoxia elevates intracellular pH and activates Na+/H+ exchange in pulmonary arterial smooth muscle cells

6 September 2017

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Na(+)/H(+) exchanger NHE1 as plasma membrane scaffold in the assembly of signaling complexes

6 September 2017

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Expression profile of genes regulated by activity of the Na-H exchanger NHE1

6 September 2017

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On respiratory impairment in cancer cells

6 September 2017

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An overview of inhibitors of Na(+)/H(+) exchanger

6 September 2017

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Carbonic anhydrase II binds to and enhances activity of the Na+/H+ exchanger

6 September 2017

1 reference

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The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

6 September 2017

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Microenvironment-induced cancer metastasis

6 September 2017

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Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion

6 September 2017

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Microinjection of ras p21 induces a rapid rise in intracellular pH.

6 September 2017

1 reference

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Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter

6 September 2017

1 reference

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Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells

6 September 2017

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Dual role of CO2/HCO3(-) buffer in the regulation of intracellular pH of three-dimensional tumor growths.

6 September 2017

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Na(V)1.5 enhances breast cancer cell invasiveness by increasing NHE1-dependent H(+) efflux in caveolae

14 September 2017

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Rapid decrease of intracellular pH associated with inhibition of Na+/H+ exchanger precedes apoptotic events in the MNK45 and MNK74 gastric cancer cell lines treated with 2-aminophenoxazine-3-one

14 September 2017

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NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance.

14 September 2017

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Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes

14 September 2017

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Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.

14 September 2017

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Acid treatment of melanoma cells selects for invasive phenotypes

14 September 2017

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The H+-linked monocarboxylate transporter (MCT1/SLC16A1): a potential therapeutic target for high-risk neuroblastoma

14 September 2017

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Na+/H+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes.

14 September 2017

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Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation

28 September 2017

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Genetic instability induced by the tumor microenvironment.

28 September 2017

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Modulation of tumor cell gene expression and phenotype by the organ-specific metastatic environment

28 September 2017

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Acidic pH enhances the invasive behavior of human melanoma cells

28 September 2017

1 reference

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Dysregulated pH: a perfect storm for cancer progression.

28 September 2017

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Luminescent gold nanoparticles with pH-dependent membrane adsorption.

23 June 2018

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B-Raf associates with and activates the NHE1 isoform of the Na+/H+ exchanger

23 June 2018

1 reference

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Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes

23 June 2018

1 reference

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Induction of v-mos and activated Ha-ras oncogene expression in quiescent NIH 3T3 cells causes intracellular alkalinisation and cell-cycle progression

23 June 2018

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23 June 2018

Are cancer cells acidic?

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Regulation of glycogen synthesis and glycolysis by insulin, pH and cell volume. Interactions between swelling and alkalinization in mediating the effects of insulin

23 June 2018

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Inhibition of Na(+)/H(+) exchanger 1 by 5-(N-ethyl-N-isopropyl) amiloride reduces hypoxia-induced hepatocellular carcinoma invasion and motility

23 June 2018

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Over-expression of Na+/H+ exchanger 1 and its clinicopathologic significance in hepatocellular carcinoma.

31 August 2018

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A novel carbonic anhydrase II binding site regulates NHE1 activity

31 August 2018

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Na+/H+ exchanger activity is increased in doxorubicin-resistant human colon cancer cells and its modulation modifies the sensitivity of the cells to doxorubicin

31 August 2018

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Regulation of intracellular pH in human melanoma: potential therapeutic implications.

31 August 2018

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Novel, non-acylguanidine-type Na(+)/H(+) exchanger inhibitors: synthesis and pharmacology of 5-tetrahydroquinolinylidene aminoguanidine derivatives

31 August 2018

1 reference

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Discovery of zoniporide: a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility

31 August 2018

1 reference

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Modifier role of internal H+ in activating the Na+–H+ exchanger in renal microvillus membrane vesicles

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1098%2FRSTB.2013.0100

(2-Methyl-5-(methylsulfonyl)benzoyl)guanidine Na+/H+ antiporter inhibitors

21 January 2018

1 reference

12 December 2020

Some recent developments in the cancer field

1 reference

12 December 2020

Blood flow, tissue oxygenation, pH distribution, and energy metabolism of murine mammary adenocarcinomas during growth

1 reference

12 December 2020

Enzymatic regulation of glycolysis and gluconeogenesis in rabbit periodontal ligament under various physiological pH conditions

1 reference

12 December 2020

Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice

1 reference

12 December 2020

Cardioprotective effect of TY-12533, a novel Na(+)/H(+) exchange inhibitor, on ischemia/reperfusion injury

1 reference

12 December 2020

NHE1 promotes invadopodial ECM proteolysis through acidification of the peri-invadopodial space

1 reference

12 December 2020

Evidence for an amiloride-insensitive Na+/H+ exchanger in rat renal cortical tubules

1 reference

12 December 2020

Influence of the host microenvironment on the clonal selection of human colon carcinoma cells during primary tumor growth and metastasis

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12 December 2020

Identifiers

DOI

10.1098/RSTB.2013.0100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24493748%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24493748%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

PubMed publication ID

24493748

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24493748%20AND%20SRC:MED&resulttype=core&format=json