Oxidative stress and metabolic syndrome: cause or consequence of Alzheimer's disease? (Q38200602)

30 August 2017

3 references

24 March 2019

25 April 2019

20 June 2019

Oxidative stress and metabolic syndrome: cause or consequence of Alzheimer's disease? (English)

1 reference

30 August 2017

3 references

24 March 2019

25 April 2019

20 June 2019

4 references

24 March 2019

25 April 2019

20 June 2019

20 September 2020

Danira Toral-Rios

3

0 references

Karla Carvajal

object named as

Karla Carvajal

2

0 references

author name string

Diana Luque-Contreras

1

1 reference

30 August 2017

Diana Franco-Bocanegra

4

1 reference

30 August 2017

Victoria Campos-Peña

5

1 reference

30 August 2017

language of work or name

1 reference

20 January 2014

5 references

Oxidative medicine and cellular longevity

30 August 2017

24 March 2019

25 April 2019

20 June 2019

20 September 2020

5 references

30 August 2017

24 March 2019

25 April 2019

20 June 2019

20 September 2020

2014

1 reference

30 August 2017

497802

1 reference

Creative Commons Attribution 3.0 Unported

30 August 2017

3 references

24 March 2019

25 April 2019

on focus list of Wikimedia project

20 June 2019

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in β-amyloid generation and Alzheimer's disease

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Angiotensin converting enzyme inhibitors and the reduced risk of Alzheimer's disease in the absence of apolipoprotein E4 allele

6 September 2017

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β-Amyloid oligomers in aging and Alzheimer's disease

6 September 2017

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Vascular risk factors and neurodegeneration in ageing related dementias: Alzheimer's disease and vascular dementia

6 September 2017

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Antihypertensives, angiotensin, glucose and Alzheimer's disease.

6 September 2017

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Vascular oxidative stress and mitochondrial failure in the pathobiology of Alzheimer's disease: a new approach to therapy

6 September 2017

1 reference

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Roles of Brain Angiotensin II in Cognitive Function and Dementia

6 September 2017

1 reference

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Vascular factors and epigenetic modifications in the pathogenesis of Alzheimer's disease

6 September 2017

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Vascular cognitive impairment and Alzheimer's disease: role of cerebral hypoperfusion and oxidative stress

6 September 2017

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Angiotensin II AT(1) receptor blockers as treatments for inflammatory brain disorders

6 September 2017

1 reference

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The axonal transport of mitochondria

6 September 2017

1 reference

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Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

6 September 2017

1 reference

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Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

6 September 2017

1 reference

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Alzheimer's disease: synapses gone cold

6 September 2017

1 reference

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Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice.

6 September 2017

1 reference

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Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease.

6 September 2017

1 reference

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Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

6 September 2017

1 reference

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Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis

6 September 2017

1 reference

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Post-translational modifications of tau protein: implications for Alzheimer's disease.

6 September 2017

1 reference

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The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension

6 September 2017

1 reference

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Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

6 September 2017

1 reference

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Probing the biology of Alzheimer's disease in mice

6 September 2017

1 reference

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Amyloid oligomers: formation and toxicity of Abeta oligomers

6 September 2017

1 reference

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Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis

6 September 2017

1 reference

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Effects of angiotensin II receptor blockers on dementia

6 September 2017

1 reference

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Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease

6 September 2017

1 reference

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Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

6 September 2017

1 reference

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Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: implications for the pathogenesis of Alzheimer disease

6 September 2017

1 reference

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The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged

6 September 2017

1 reference

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Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

6 September 2017

1 reference

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Metabolic syndrome and Alzheimer's disease: a link to a vascular hypothesis?

6 September 2017

1 reference

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Metabolic syndrome and the role of dietary lifestyles in Alzheimer's disease

6 September 2017

1 reference

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Nucleic acid oxidation in Alzheimer disease

6 September 2017

1 reference

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Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

6 September 2017

1 reference

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Renin-angiotensin system and cardiovascular risk

6 September 2017

1 reference

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The creatine kinase/creatine connection to Alzheimer's disease: CK-inactivation, APP-CK complexes and focal creatine deposits

6 September 2017

1 reference

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Apolipoprotein E structure: insights into function.

6 September 2017

1 reference

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Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Neurovascular mechanisms of Alzheimer's neurodegeneration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

The critical role of methionine 35 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Alzheimer's disease is a vasocognopathy: a new term to describe its nature

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Alzheimer's amyloid beta-peptide (1-42): involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Neurovascular regulation in the normal brain and in Alzheimer's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Initiation of neuronal damage by complex I deficiency and oxidative stress in Parkinson's disease.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Coupled reductions in brain oxidative phosphorylation and synaptic function can be quantified and staged in the course of Alzheimer disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Methionine residue 35 is critical for the oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide 1-42.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Oxidative stress in synaptosomal proteins from mutant presenilin-1 knock-in mice: implications for familial Alzheimer's disease.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Role of apoe/Abeta interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Neuropathological stageing of Alzheimer-related changes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: a laser microprobe (LAMMA) study

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

A protein factor essential for microtubule assembly

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Preparation and characterization of neurotoxic tau oligomers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Effect of apoE genotype and vitamin E on biomarkers of oxidative stress in cultured neuronal cells and the brain of targeted replacement mice.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Mitochondrial bioenergetics and structural network organization

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

SDS-stable complex formation between native apolipoprotein E3 and beta-amyloid peptides

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

The pathogenesis of cardiovascular disease: role of the endothelium as a target and mediator

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Sites of tau important for aggregation populate {beta}-structure and bind to microtubules and polyanions

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Cerebrovascular dysfunction in Zucker obese rats is mediated by oxidative stress and protein kinase C.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Mitochondrial respiratory chain Complexes I and IV are impaired by β-amyloid via direct interaction and through Complex I-dependent ROS production, respectively.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Hormetic effect of amyloid-β peptide in synaptic plasticity and memory.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Associations of anti-hypertensive treatments with Alzheimer's disease, vascular dementia, and other dementias

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Perindopril, a centrally active angiotensin-converting enzyme inhibitor, prevents cognitive impairment in mouse models of Alzheimer's disease.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Angiotensin receptor blocker prevented beta-amyloid-induced cognitive impairment associated with recovery of neurovascular coupling

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Association between enzymatic and non-enzymatic antioxidant defense mechanism with apolipoprotein E genotypes in Alzheimer disease

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Peroxynitrite induces Alzheimer-like tau modifications and accumulation in rat brain and its underlying mechanisms

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

N-acteyl cysteine alleviates oxidative damage to central nervous system of ApoE-deficient mice following folate and vitamin E-deficiency.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Structural and behavioural consequences of double deficiency for creatine kinases BCK and UbCKmit

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

beta-Amyloid induces paired helical filament-like tau filaments in tissue culture

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Regional cerebral metabolic alterations in dementia of the Alzheimer type: positron emission tomography with [18F]fluorodeoxyglucose

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941786

Ca2+-induced increased lipid packing and domain formation in submitochondrial particles. A possible early step in the mechanism of Ca2+-stimulated generation of reactive oxygen species by the respiratory chain

31 August 2018

1 reference

12 December 2020

Increased plasma and lipoprotein lipid peroxidation in apo E-deficient mice

1 reference

12 December 2020

Relationship between synaptogenesis and cytochrome oxidase activity in Purkinje cells of the developing rat cerebellum

1 reference

12 December 2020

Short- and long-term alterations of mitochondrial morphology, dynamics and mtDNA after transient oxidative stress

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/497802

1 reference

30 August 2017

1 reference

30 August 2017

PubMed publication ID

24683436

1 reference