Amyloid beta receptors responsible for neurotoxicity and cellular defects in Alzheimer's disease (Q38242621)

31 August 2017

title

Amyloid beta receptors responsible for neurotoxicity and cellular defects in Alzheimer's disease (English)

1 reference

31 August 2017

0 references

1 reference

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3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151011%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Tae-In Kam

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151011%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Youngdae Gwon

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151011%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Tae-In Kam

1

1 reference

31 August 2017

Youngdae Gwon

2

1 reference

31 August 2017

publication date

24 August 2014

1 reference

Cellular and Molecular Life Sciences

31 August 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151011%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

71

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151011%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

24

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151011%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

4803-4813

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25151011%20AND%20SRC:MED&resulttype=core&format=json

Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation.

5 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Novel APP mutation V715A associated with presenile Alzheimer's disease in a German family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Autosomal-dominant Alzheimer's disease mutations at the same codon of amyloid precursor protein differentially alter Aβ production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Calcium dyshomeostasis and neurotoxicity of Alzheimer's beta-amyloid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

In situ Abeta pores in AD brain are cylindrical assembly of Abeta protofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Effects of beta-amyloid-(25-35) peptides on radioligand binding to excitatory amino acid receptors and voltage-dependent calcium channels: evidence for a selective affinity for the glutamate and glycine recognition sites of the NMDA receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Human LilrB2 is a β-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Evidence for altered LRP/RAGE expression in Alzheimer lesion pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Advanced glycation end products in Alzheimer's disease and other neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Receptor for Advanced Glycation Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes & aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Clinical trial of an inhibitor of RAGE-Aβ interactions in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-β oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

N-methyl-D-aspartate receptors are required for synaptic targeting of Alzheimer's toxic amyloid-β peptide oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Neuronal receptors as targets for the action of amyloid-beta protein (Aβ) in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Regulation of NMDA receptor trafficking by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Alpha 7 nicotinic acetylcholine receptors mediate beta-amyloid peptide-induced tau protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Memory impairment in transgenic Alzheimer mice requires cellular prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an Alzheimer's disease model mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

The prion protein as a receptor for amyloid-beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Prion protein and Abeta-related synaptic toxicity impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Ablation of cellular prion protein does not ameliorate abnormal neural network activity or cognitive dysfunction in the J20 line of human amyloid precursor protein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Immunoglobulin G Fc receptor deficiency prevents Alzheimer-like pathology and cognitive impairment in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Signal integration in the endoplasmic reticulum unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Ca2+ signaling and calcium binding chaperones of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Amyloid-beta-(1-42) increases ryanodine receptor-3 expression and function in neurons of TgCRND8 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

The ER stress factor XBP1s prevents amyloid-beta neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Cytotoxicity of intracellular aβ42 amyloid oligomers involves Ca2+ release from the endoplasmic reticulum by stimulated production of inositol trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

E2-25K/Hip-2 regulates caspase-12 in ER stress-mediated Abeta neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Human caspase 12 has acquired deleterious mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Caspase-4 is partially cleaved by calpain via the impairment of Ca2+ homeostasis under the ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Mitochondrial accumulation of APP and Abeta: significance for Alzheimer disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

The micro-architecture of mitochondria at active zones: electron tomography reveals novel anchoring scaffolds and cristae structured for high-rate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Mitochondrial transport and docking in axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

The axonal transport of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Down-regulation of mortalin exacerbates Aβ-mediated mitochondrial fragmentation and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Tau promotes neurodegeneration via DRP1 mislocalization in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Abeta polymerization through interaction with membrane gangliosides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Internalization of beta-amyloid peptide by primary neurons in the absence of apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

MEGF10 functions as a receptor for the uptake of amyloid‐β

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Abeta42 uptake and lysosomal trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Activation of Toll-like receptor 2 on microglia promotes cell uptake of Alzheimer disease-associated amyloid beta peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Role of toll-like receptor signalling in Abeta uptake and clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Membrane-bound β-amyloid oligomers are recruited into lipid rafts by a fyn-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1706-0

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

21 January 2018

1 reference

12 December 2020

Early changes in neurons of the hippocampus and neocortex in transgenic rats expressing intracellular human a-beta.

1 reference

12 December 2020

Fresh and globular amyloid beta protein (1-42) induces rapid cellular degeneration: evidence for AbetaP channel-mediated cellular toxicity

1 reference

12 December 2020

The non-amyloidogenic pathway: structure and function of alpha-secretases

1 reference

12 December 2020

RAGE: a potential target for Abeta-mediated cellular perturbation in Alzheimer's disease

1 reference

12 December 2020

Intraneuronal Abeta42 accumulation in Down syndrome brain

1 reference

12 December 2020

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

1 reference

12 December 2020

Salubrinal attenuates β-amyloid-induced neuronal death and microglial activation by inhibition of the NF-κB pathway

1 reference

12 December 2020

PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.

1 reference

12 December 2020

Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons

1 reference

12 December 2020

Mechanisms of amyloid-Beta Peptide uptake by neurons: the role of lipid rafts and lipid raft-associated proteins

1 reference

12 December 2020

Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease

1 reference

12 December 2020

Early neuronal dysfunction by amyloid β oligomers depends on activation of NR2B-containing NMDA receptors

1 reference

12 December 2020

Amyloid β-induced FOXRED2 mediates neuronal cell death via inhibition of proteasome activity

1 reference

12 December 2020