MicroRNAs in kidney physiology and disease (Q38266791)

1 September 2017

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title

MicroRNAs in kidney physiology and disease (English)

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1 September 2017

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Ariela Benigni

2

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Giuseppe Remuzzi

object named as

Giuseppe Remuzzi

series ordinal

3

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Piera Trionfini

series ordinal

1

object named as

Piera Trionfini

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PubMed ID

25385286

1 September 2017

language of work or name

English

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publication date

11 November 2014

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Nature Reviews Nephrology

1 September 2017

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1 September 2017

11

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1 September 2017

23-33

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1 September 2017

1

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https://scigraph.springernature.com/pub.10.1038/nrneph.2014.202

1 September 2017

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31 March 2020

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Circulating and urinary microRNAs in kidney disease.

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MicroRNAs and epigenetic regulation in the mammalian inner ear: implications for deafness

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The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injury

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The widespread regulation of microRNA biogenesis, function and decay

31 March 2020

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Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes

31 March 2020

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Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-{beta}-induced collagen expression in kidney cells.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR

31 March 2020

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miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay

31 March 2020

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Gene silencing by microRNAs: contributions of translational repression and mRNA decay

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-373 induces expression of genes with complementary promoter sequences

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-214 antagonism protects against renal fibrosis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA degradation and turnover: regulating the regulators

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

A mammalian microRNA expression atlas based on small RNA library sequencing

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Quantitative analysis of miRNA expression in seven human foetal and adult organs

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

The pro-apoptotic protein Bim is a microRNA target in kidney progenitors

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-17~92 is required for nephrogenesis and renal function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNAs regulate renal tubule maturation through modulation of Pkd1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

The next level of complexity: post-transcriptional regulation by microRNAs.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Targeted deletion of Dicer from proximal tubules protects against renal ischemia-reperfusion injury.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNAs as mediators and therapeutic targets in chronic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

The microRNA-processing enzyme dicer maintains juxtaglomerular cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNAs contribute to the maintenance of cell-type-specific physiological characteristics: miR-192 targets Na+/K+-ATPase β1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Regulation of WNK1 expression by miR-192 and aldosterone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Aldosterone regulates microRNAs in the cortical collecting duct to alter sodium transport.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Tonicity-responsive microRNAs contribute to the maximal induction of osmoregulatory transcription factor OREBP in response to high-NaCl hypertonicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA 802 stimulates ROMK channels by suppressing caveolin-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-194 (miR-194) regulates ROMK channel activity by targeting intersectin 1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Claudin-14 regulates renal Ca⁺⁺ transport in response to CaSR signalling via a novel microRNA pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Claudin-14 underlies Ca⁺⁺-sensing receptor-mediated Ca⁺⁺ metabolism via NFAT-microRNA-based mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Essential role of TGF-beta signaling in glucose-induced cell hypertrophy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Angiotensin II as a morphogenic cytokine stimulating renal fibrogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

NADPH oxidase-dependent redox signaling in TGF-β-mediated fibrotic responses.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Chronic kidney disease growth factors in renal fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

The origin of scar-forming kidney myofibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Origin and function of myofibroblasts in kidney fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

The role of plasminogen activator inhibitor 1 in renal and cardiovascular diseases.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Crosstalk between TGF-β signaling and the microRNA machinery

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

SMAD proteins control DROSHA-mediated microRNA maturation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Smad3-mediated upregulation of miR-21 promotes renal fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

miR-192 mediates TGF-beta/Smad3-driven renal fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-beta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

TGF-β induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Roles of HNF-1beta in kidney development and congenital cystic diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Transforming growth factor-β-induced cross talk between p53 and a microRNA in the pathogenesis of diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Suppression of microRNA-29 expression by TGF-β1 promotes collagen expression and renal fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Canonical transforming growth factor-β signaling regulates disintegrin metalloprotease expression in experimental renal fibrosis via miR-29.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-29b inhibits diabetic nephropathy in db/db mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-324-3p promotes renal fibrosis and is a target of ACE inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MiRNA-200b represses transforming growth factor-β1-induced EMT and fibronectin expression in kidney proximal tubular cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

The miR-200 family regulates TGF-β1-induced renal tubular epithelial to mesenchymal transition through Smad pathway by targeting ZEB1 and ZEB2 expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Loss of MicroRNA-192 promotes fibrogenesis in diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

A microRNA-30e/mitochondrial uncoupling protein 2 axis mediates TGF-β1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

miR-21 and miR-214 are consistently modulated during renal injury in rodent models

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-21 protects from mesangial cell proliferation induced by diabetic nephropathy in db/db mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Diabetes complications: the microRNA perspective.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

FOG2 protein down-regulation by transforming growth factor-β1-induced microRNA-200b/c leads to Akt kinase activation and glomerular mesangial hypertrophy related to diabetic nephropathy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Lipoxins attenuate renal fibrosis by inducing let-7c and suppressing TGFβR1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Tongxinluo ameliorates renal structure and function by regulating miR-21-induced epithelial-to-mesenchymal transition in diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-29a promotion of nephrin acetylation ameliorates hyperglycemia-induced podocyte dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Regulation of NADPH oxidase activity is associated with miRNA-25-mediated NOX4 expression in experimental diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Identification of microRNA-93 as a novel regulator of vascular endothelial growth factor in hyperglycemic conditions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Urinary microRNA profiling in the nephropathy of type 1 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Urinary exosomal microRNAs in incipient diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Micro-RNA expression in the urinary sediment of patients with chronic kidney diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Abnormal miR-148b expression promotes aberrant glycosylation of IgA1 in IgA nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Intrarenal expression of microRNAs in patients with IgA nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Elevated levels of miR-146a and miR-155 in kidney biopsy and urine from patients with IgA nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MiR-223 downregulation promotes glomerular endothelial cell activation by upregulating importin α4 and α5 in IgA nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Urinary miR-21, miR-29, and miR-93: novel biomarkers of fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Comprehensive analysis of microRNA expression patterns in renal biopsies of lupus nephritis patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

miR-150 promotes renal fibrosis in lupus nephritis by downregulating SOCS1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Post-transcriptional gene regulation makes things clearer in renal fibrosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Glomerular and tubulointerstitial miR-638, miR-198 and miR-146a expression in lupus nephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Circulating microRNA expression profiles associated with systemic lupus erythematosus.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Urinary sediment ICAM-1 level in lupus nephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Identification of unique microRNA signature associated with lupus nephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Biomarker profiling for lupus nephritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

miR-17~92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA-17 post-transcriptionally regulates polycystic kidney disease-2 gene and promotes cell proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Bicc1 links the regulation of cAMP signaling in polycystic kidneys to microRNA-induced gene silencing.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Microarray-based approach identifies microRNAs and their target functional patterns in polycystic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Parallel analysis of mRNA and microRNA microarray profiles to explore functional regulatory patterns in polycystic kidney disease: using PKD/Mhm rat model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: description of miRNA profiles at baseline

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Microarray analysis of MicroRNA expression in acute rejection after renal transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA expression profiles predictive of human renal allograft status

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

miRNA profiling discriminates types of rejection and injury in human renal allografts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Urinary miR-210 as a mediator of acute T-cell mediated rejection in renal allograft recipients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Upregulation of miR-142-3p in peripheral blood mononuclear cells of operationally tolerant patients with a renal transplant

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA profiles in allograft tissues and paired urines associate with chronic allograft dysfunction with IF/TA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

MicroRNA sequence profiles of human kidney allografts with or without tubulointerstitial fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

The urine microRNA profile may help monitor post-transplant renal graft function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Treatment of HCV infection by targeting microRNA

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2014.202

Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25385286

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Smad regulation in TGF-beta signal transduction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25385286

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRNEPH.2014.202

1 reference

1 September 2017

1 reference

PubMed ID

25385286