Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma. (Q38438763)

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scientific article published on 03 March 2017

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English	Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma.	scientific article published on 03 March 2017

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20 March 2020

Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma (English)

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20 March 2020

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Abhishek D. Garg

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20 March 2020

Patrizia Agostinis

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20 March 2020

Steven De Vleeschouwer

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20 March 2020

Lien Vandenberk

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Lien Vandenberk

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20 March 2020

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Louis Boon

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20 March 2020

Matthias Van Woensel

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Matthias Van Woensel

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20 March 2020

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Jochen Belmans

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20 March 2020

Marco B E Schaaf

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Marco Schaaf

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20 March 2020

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3 March 2017

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20 March 2020

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20 March 2020

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20 March 2020

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20 March 2020

e1295903

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20 March 2020

Immunosuppressive tumor-infiltrating myeloid cells mediate adaptive immune resistance via a PD-1/PD-L1 mechanism in glioblastoma.

1 reference

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23 June 2018

Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy.

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The movers and shapers in immune privilege of the CNS.

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Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

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Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM.

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T Cell Exhaustion in Glioblastoma: Intricacies of Immune Checkpoints

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Immunovirotherapy with measles virus strains in combination with anti-PD-1 antibody blockade enhances antitumor activity in glioblastoma treatment

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PD-1 blockade enhances the vaccination-induced immune response in glioma

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Mutational Landscape and Sensitivity to Immune Checkpoint Blockers

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Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas

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CANCER IMMUNOLOGY. The "cancer immunogram".

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Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma

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23 June 2018

Immunological metagene signatures derived from immunogenic cancer cell death associate with improved survival of patients with lung, breast or ovarian malignancies: A large-scale meta-analysis

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Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency.

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Immunogenic versus tolerogenic phagocytosis during anticancer therapy: mechanisms and clinical translation

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Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.

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23 June 2018

Synergistic antitumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model

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Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

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23 June 2018

Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model

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23 June 2018

Combination viroimmunotherapy with checkpoint inhibition to treat glioma, based on location-specific tumor profiling

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23 June 2018

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

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Resistance to anticancer vaccination effect is controlled by a cancer cell-autonomous phenotype that disrupts immunogenic phagocytic removal

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23 June 2018

Prospects of immune checkpoint modulators in the treatment of glioblastoma

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The prognostic landscape of genes and infiltrating immune cells across human cancers

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23 June 2018

Therapeutic administration of IL-15 superagonist complex ALT-803 leads to long-term survival and durable antitumor immune response in a murine glioblastoma model

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Pembrolizumab versus Ipilimumab in Advanced Melanoma

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The future of immune checkpoint therapy

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Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

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Active dendritic cell immunotherapy for glioblastoma: Current status and challenges

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23 June 2018

Newcastle disease virotherapy induces long-term survival and tumor-specific immune memory in orthotopic glioma through the induction of immunogenic cell death

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23 June 2018

The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma

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Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model

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Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection

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Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas

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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

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DC vaccination with anti-CD25 treatment leads to long-term immunity against experimental glioma.

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23 June 2018

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

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12 December 2020

based on heuristic

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In Vitro Generation of Murine Dendritic Cells for Cancer Immunotherapy: An Optimized Protocol

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12 December 2020

based on heuristic

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Identifiers

10.1080/2162402X.2017.1295903

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507806%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507806%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507806%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

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