Foxp3+ regulatory T cells are activated in spite of B7-CD28 and CD40-CD40L blockade (Q85954238)

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22 February 2020

title

Foxp3+ regulatory T cells are activated in spite of B7-CD28 and CD40-CD40L blockade (English)

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22 February 2020

1

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22 February 2020

Jan L Ceuppens

6

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22 February 2020

author name string

Bert Verbinnen

2

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22 February 2020

Wim Maes

3

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22 February 2020

Louis Boon

4

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22 February 2020

Stefaan W Van Gool

5

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22 February 2020

publication date

22 February 2013

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European Journal of Immunology

22 February 2020

published in

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22 February 2020

volume

43

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22 February 2020

page(s)

1013-1023

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22 February 2020

issue

4

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Regulatory T cells exert checks and balances on self tolerance and autoimmunity

22 February 2020

cites work

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7 January 2021

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

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Regulatory T cell lineage specification by the forkhead transcription factor foxp3

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Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

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7 January 2021

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

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Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency.

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A low interleukin-2 receptor signaling threshold supports the development and homeostasis of T regulatory cells

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Molecular mechanisms of regulatory T cell development and suppressive function.

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7 January 2021

Activation and inhibition of lymphocytes by costimulation

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Induction of immunologic tolerance for allogeneic hematopoietic cell transplantation

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Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

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The B7-CD28 superfamily

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Blocking costimulatory pathways: prospects for inducing transplantation tolerance.

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Costimulation blockade in autoimmunity and transplantation

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7 January 2021

CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade

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7 January 2021

Contribution of regulatory T cells and effector T cell deletion in tolerance induction by costimulation blockade.

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7 January 2021

Cardiac allograft acceptance induced by blockade of CD40-CD40L costimulation is dependent on CD4+CD25+ regulatory T cells

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7 January 2021

CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

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7 January 2021

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

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7 January 2021

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

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7 January 2021

CTLA-4 control over Foxp3+ regulatory T cell function

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7 January 2021

ICOS deficiency results in exacerbated IL-17 mediated experimental autoimmune encephalomyelitis.

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7 January 2021

Down-modulation of programmed death 1 alters regulatory T cells and promotes experimental autoimmune encephalomyelitis

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7 January 2021

GITR ligand-costimulation activates effector and regulatory functions of CD4+ T cells

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7 January 2021

Ex vivo expansion of CD4+CD25+FoxP3+ T regulatory cells based on synergy between IL-2 and 4-1BB signaling

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7 January 2021

Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells

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7 January 2021

Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

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7 January 2021

Dendritic cells as a tool to induce anergic and regulatory T cells

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7 January 2021

Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?

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7 January 2021

Immature and mature CD8alpha+ dendritic cells prolong the survival of vascularized heart allografts

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7 January 2021

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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7 January 2021

Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus

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7 January 2021

CD28 costimulation regulates FOXP3 in a RelA/NF-κB-dependent mechanism.

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7 January 2021

Inducing and expanding regulatory T cell populations by foreign antigen

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7 January 2021

Choice of resident costimulatory molecule can influence cell fate in human naïve CD4+ T cell differentiation

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7 January 2021

Interleukin-2 is essential for CD4+CD25+ regulatory T cell function

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7 January 2021

Interleukin 2 regulates expression of its receptor and synthesis of gamma interferon by human T lymphocytes

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7 January 2021

CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production.

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7 January 2021

Identifiers

DOI

10.1002/EJI.201242737

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23348953%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

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