Development and function of follicular helper T cells (Q38539784)

3 September 2017

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title

Development and function of follicular helper T cells (English)

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3 September 2017

Wataru Ise

1

1 reference

3 September 2017

publication date

29 June 2015

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Bioscience, Biotechnology, and Biochemistry

3 September 2017

published in

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3 September 2017

volume

80

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3 September 2017

issue

1

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3 September 2017

page(s)

1-6

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https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

3 September 2017

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Germinal-center organization and cellular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

21 January 2018

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https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Follicular helper CD4 T cells (TFH)

21 January 2018

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https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

In vivo-activated CD4 T cells upregulate CXC chemokine receptor 5 and reprogram their response to lymphoid chemokines

21 January 2018

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https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

21 January 2018

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https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Separable effector T cell populations specialized for B cell help or tissue inflammation

21 January 2018

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https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Human tonsil B-cell lymphoma 6 (BCL6)-expressing CD4+ T-cell subset specialized for B-cell help outside germinal centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Bcl6 mediates the development of T follicular helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Bcl6 expression specifies the T follicular helper cell program in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Cytokine-secreting follicular T cells shape the antibody repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Functional diversity of helper T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

The cytokine TGF-β co-opts signaling via STAT3-STAT4 to promote the differentiation of human TFH cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Development and characterization of IL-21-producing CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Th9 cell development requires a BATF-regulated transcriptional network

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

A validated regulatory network for Th17 cell specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Helper T-cell identity and evolution of differential transcriptomes and epigenomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Transcription factor Foxp1 exerts essential cell-intrinsic regulation of the quiescence of naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

STAT5 is a potent negative regulator of TFH cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Clonal selection in the germinal centre by regulated proliferation and hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

T follicular helper cell dynamics in germinal centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Distinct memory CD4+ T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Memory B cells contribute to rapid Bcl6 expression by memory follicular helper T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Phenotype and functions of memory Tfh cells in human blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

Memory CD4 T cells that express CXCR5 provide accelerated help to B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09168451.2015.1056512

10.1080/09168451.2015.1056512

21 January 2018

Identifiers

DOI

1 reference

3 September 2017

1 reference