Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells (Q37711709)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24631156%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells (English)

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10 March 2020

1

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10 March 2020

author name string

Heather D Marshall

2

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10 March 2020

Brian J Laidlaw

3

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10 March 2020

Matthew M Staron

4

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10 March 2020

Susan M Kaech

5

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10 March 2020

Joe Craft

6

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10 March 2020

language of work or name

English

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publication date

13 March 2014

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10 March 2020

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10 March 2020

volume

40

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10 March 2020

issue

3

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10 March 2020

page(s)

367-377

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Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection.

10 March 2020

cites work

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Distinct memory CD4+ T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection.

23 August 2017

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B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1

23 August 2017

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Follicular helper T cells in immunity and systemic autoimmunity

23 August 2017

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Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile

23 August 2017

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Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

23 August 2017

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STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function.

23 August 2017

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STAT5 is a potent negative regulator of TFH cell differentiation

23 August 2017

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Early Th1 cell differentiation is marked by a Tfh cell-like transition

23 August 2017

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Molecular programming of B cell memory

23 August 2017

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Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection

23 August 2017

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Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells.

23 August 2017

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Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection

23 August 2017

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Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone

23 August 2017

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IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation

23 August 2017

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Follicular helper CD4 T cells (TFH)

23 August 2017

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IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.

23 August 2017

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In vivo regulation of Bcl6 and T follicular helper cell development

23 August 2017

1 reference

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IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

23 August 2017

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IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

23 August 2017

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Bcl6 mediates the development of T follicular helper cells

23 August 2017

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Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

23 August 2017

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Follicular helper T cells are required for systemic autoimmunity

23 August 2017

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Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome

23 August 2017

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A fundamental role for interleukin-21 in the generation of T follicular helper cells

23 August 2017

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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

23 August 2017

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Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells

23 August 2017

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Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

23 August 2017

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Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

23 August 2017

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23 August 2017

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IL-12 and type-I IFN synergize for IFN-gamma production by CD4 T cells, whereas neither are required for IFN-gamma production by CD8 T cells after Listeria monocytogenes infection

23 August 2017

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Cutting Edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection

23 August 2017

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A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation

23 August 2017

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Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways

14 September 2017

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An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells

14 September 2017

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ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6

23 June 2018

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The transcription factor STAT3 is required for T helper 2 cell development

23 June 2018

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STAT3 negatively regulates type I IFN-mediated antiviral response.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992517

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992517

Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles

1 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3992517

Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation.

1 September 2018

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Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

1 September 2018

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Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection

1 September 2018

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Blocking Monoclonal Antibodies Specific for Mouse IFN-α/β Receptor Subunit 1 (IFNAR-1) from Mice Immunized by In Vivo Hydrodynamic Transfection

1 September 2018

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Interferon-γ excess leads to pathogenic accumulation of follicular helper T cells and germinal centers

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24631156

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12 December 2020

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Identifiers

DOI

10.1016/J.IMMUNI.2014.02.005

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10 March 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/pbc2jszy5jg33f6rldo6umm5oa

mapped directly with Wikidata item

24 November 2022

based on heuristic

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10 March 2020

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