The development and fate of follicular helper T cells defined by an IL-21 reporter mouse. (Q50499734)

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27 January 2020

title

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse (English)

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27 January 2020

4

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27 January 2020

Stephen L. Nutt

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27 January 2020

Axel Kallies

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27 January 2020

David M Tarlinton

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27 January 2020

author name string

Katja Lüthje

1

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27 January 2020

Yoko Shimohakamada

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27 January 2020

Amanda Light

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27 January 2020

language of work or name

English

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publication date

1 May 2012

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27 January 2020

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27 January 2020

volume

13

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issue

5

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27 January 2020

page(s)

491-498

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Differentiation of effector CD4 T cell populations (*)

27 January 2020

cites work

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Effector T cell plasticity: flexibility in the face of changing circumstances

21 January 2018

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Follicular helper CD4 T cells (TFH)

21 January 2018

1 reference

The elusive identity of T follicular helper cells

21 January 2018

1 reference

Germinal center B and follicular helper T cells: siblings, cousins or just good friends?

21 January 2018

1 reference

In vivo-activated CD4 T cells upregulate CXC chemokine receptor 5 and reprogram their response to lymphoid chemokines

21 January 2018

1 reference

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

21 January 2018

1 reference

Separable effector T cell populations specialized for B cell help or tissue inflammation

21 January 2018

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T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

21 January 2018

1 reference

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

21 January 2018

1 reference

IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production

21 January 2018

1 reference

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

21 January 2018

1 reference

Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

21 January 2018

1 reference

B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells

21 January 2018

1 reference

A critical role for IL-21 in regulating immunoglobulin production

21 January 2018

1 reference

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

21 January 2018

1 reference

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

21 January 2018

1 reference

The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo

21 January 2018

1 reference

Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

21 January 2018

1 reference

Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation.

21 January 2018

1 reference

Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling.

21 January 2018

1 reference

A fundamental role for interleukin-21 in the generation of T follicular helper cells

21 January 2018

1 reference

Bcl6 mediates the development of T follicular helper cells

21 January 2018

1 reference

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

21 January 2018

1 reference

Lymphoid reservoirs of antigen-specific memory T helper cells

21 January 2018

1 reference

The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells

21 January 2018

1 reference

Development and characterization of IL-21-producing CD4+ T cells

21 January 2018

1 reference

Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors

21 January 2018

1 reference

IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype

21 January 2018

1 reference

Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)

21 January 2018

1 reference

T follicular helper cells differentiate from Th2 cells in response to helminth antigens

21 January 2018

1 reference

Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

21 January 2018

1 reference

Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection

21 January 2018

1 reference

Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells.

21 January 2018

1 reference

Cytokine-secreting follicular T cells shape the antibody repertoire

21 January 2018

1 reference

Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity.

21 January 2018

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ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6

21 January 2018

1 reference

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

21 January 2018

1 reference

Phenotypical and functional specialization of FOXP3+ regulatory T cells

21 January 2018

1 reference

Local development of effector and memory T helper cells.

21 January 2018

1 reference

Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development.

21 January 2018

1 reference

The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease

21 January 2018

1 reference

Virus-specific CD8+ T cells in primary and secondary influenza pneumonia

21 January 2018

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Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22466669