Genetic deficiency and polymorphisms of cyclophilin A reveal its essential role for Human Coronavirus 229E replication (Q38576023)

4 September 2017

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12 July 2022

22 August 2022

22 October 2022

Genetic deficiency and polymorphisms of cyclophilin A reveal its essential role for Human Coronavirus 229E replication (English)

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4 September 2017

main subject

Human coronavirus 229E

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peptidylprolyl isomerase A

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viral genome replication

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Human coronavirus

object named as

Human Coronavirus

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2

Sandra Ciesek

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318518%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Albrecht von Brunn

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318518%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Brigitte von Brunn

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318518%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Javier Carbajo-Lozoya

series ordinal

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318518%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

26 August 2015

1 reference

Current opinion in virology

4 September 2017

1 October 2015

3 references

12 July 2022

22 August 2022

22 October 2022

4 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318518%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

12 July 2022

22 August 2022

22 October 2022

14

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1 June 2020

page(s)

56-61

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Antiviral drugs specific for coronaviruses in preclinical development

1 June 2020

cites work

1 reference

12 December 2020

Active-site residues of cyclophilin A are crucial for its incorporation into human immunodeficiency virus type 1 virions.

1 reference

12 December 2020

Cyclophilin A Is an Essential Cofactor for Hepatitis C Virus Infection and the Principal Mediator of Cyclosporine Resistance In Vitro

1 reference

12 December 2020

Vanishingly low levels of Ess1 prolyl-isomerase activity are sufficient for growth in Saccharomyces cerevisiae

1 reference

12 December 2020

Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus

1 reference

12 December 2020

Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3.

1 reference

12 December 2020

Hepatocytes that express variants of cyclophilin A are resistant to HCV infection and replication

1 reference

12 December 2020

Hepatitis C virus and interferon type III (interferon-λ3/interleukin-28B and interferon-λ4): genetic basis of susceptibility to infection and response to antiviral treatment.

1 reference

12 December 2020

The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro

1 reference

12 December 2020

CD209 (DC-SIGN) -336A>G promoter polymorphism and severe acute respiratory syndrome in Hong Kong Chinese.

1 reference

12 December 2020

Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection

1 reference

12 December 2020

SARS--beginning to understand a new virus

1 reference

12 December 2020

Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid

1 reference

12 December 2020

Multidomain Peptidyl Prolyl cis/trans Isomerases

1 reference

12 December 2020

From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design

1 reference

12 December 2020

Cyclophilin A: a key player for human disease

1 reference

12 December 2020

Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group

1 reference

12 December 2020

Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir

1 reference

12 December 2020

X-ray structure of a monomeric cyclophilin A-cyclosporin A crystal complex at 2.1 A resolution

1 reference

12 December 2020

The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.

1 reference

12 December 2020

The Isomerase Active Site of Cyclophilin A Is Critical for Hepatitis C Virus Replication

1 reference

12 December 2020

Suppression of feline coronavirus replication in vitro by cyclosporin A.

1 reference

12 December 2020

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

1 reference

12 December 2020

MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

1 reference

12 December 2020

Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506.

1 reference

12 December 2020

Efficient hepatitis C virus cell culture system: what a difference the host cell makes

1 reference

12 December 2020

Identification and genotyping of feline infectious peritonitis-associated single nucleotide polymorphisms in the feline interferon-γ gene

1 reference

12 December 2020

Evaluation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811.

1 reference

12 December 2020

Fine tuning the inhibition profile of cyclosporine A by derivatization of the MeBmt residue

1 reference

12 December 2020

NIM811, a Cyclophilin Inhibitor, Exhibits Potent In Vitro Activity against Hepatitis C Virus Alone or in Combination with Alpha Interferon

1 reference

12 December 2020

Alternative screening approaches for discovery of Middle East respiratory syndrome coronavirus inhibitors

1 reference

12 December 2020

Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A.

1 reference

12 December 2020

SCY-635, a Novel Nonimmunosuppressive Analog of Cyclosporine That Exhibits Potent Inhibition of Hepatitis C Virus RNA Replication In Vitro

1 reference

12 December 2020

Anti-inflammatory effects of extracellular cyclosporins are exclusively mediated by CD147.

1 reference

12 December 2020

A genome-wide association study identifies major loci affecting the immune response against infectious bronchitis virus in chicken

1 reference

12 December 2020

Cyclosporin A inhibits the replication of diverse coronaviruses

1 reference

12 December 2020

SARS-CoV ORF1b-encoded nonstructural proteins 12-16: replicative enzymes as antiviral targets.

1 reference

12 December 2020

Human coronavirus-induced neuronal programmed cell death is cyclophilin d dependent and potentially caspase dispensable

1 reference

12 December 2020

Coronaviruses post-SARS: update on replication and pathogenesis

1 reference

12 December 2020

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1 reference

12 December 2020

Polymorphisms in the feline TNFA and CD209 genes are associated with the outcome of feline coronavirus infection

1 reference

12 December 2020

Identification of a new human coronavirus

1 reference

12 December 2020

Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia

1 reference

12 December 2020

Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture

1 reference

12 December 2020

The role of immunophilins in viral infection

1 reference

12 December 2020

Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

1 reference

12 December 2020

The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein

1 reference

12 December 2020

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors

1 reference

12 December 2020

Bioengineering and semisynthesis of an optimized cyclophilin inhibitor for treatment of chronic viral infection

1 reference

12 December 2020

Genetic variability of human coronavirus OC43-, 229E-, and NL63-like strains and their association with lower respiratory tract infections of hospitalized infants and immunocompromised patients

1 reference

12 December 2020

Nasopharyngeal shedding of severe acute respiratory syndrome-associated coronavirus is associated with genetic polymorphisms.

1 reference

12 December 2020

NFAT proteins: key regulators of T-cell development and function

1 reference

12 December 2020

10.1016/J.COVIRO.2015.08.004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318518%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

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1 June 2020

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