Autophagy and autophagy-related proteins in the immune system (Q38588827)

4 September 2017

Autophagy and autophagy-related proteins in the immune system (English)

1 reference

4 September 2017

0 references

5

Tamotsu Yoshimori

1 reference

4 September 2017

Shusaku T Shibutani

1

1 reference

4 September 2017

Tatsuya Saitoh

series ordinal

2

1 reference

4 September 2017

Heike Nowag

series ordinal

3

1 reference

4 September 2017

Christian Münz

series ordinal

4

1 reference

4 September 2017

language of work or name

English

0 references

publication date

1 September 2015

1 reference

4 September 2017

1 reference

4 September 2017

16

1 reference

4 September 2017

1014-1024

1 reference

4 September 2017

10

1 reference

Autophagy: renovation of cells and tissues

4 September 2017

1 reference

Historical landmarks of autophagy research

21 January 2018

1 reference

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

21 January 2018

1 reference

The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella

21 January 2018

1 reference

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

21 January 2018

1 reference

Autophagosomes form at ER-mitochondria contact sites

21 January 2018

1 reference

WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.

21 January 2018

1 reference

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

21 January 2018

1 reference

Dynamics and diversity in autophagy mechanisms: lessons from yeast

21 January 2018

1 reference

Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: analysis of the organization of the Atg16L1 complex in fibroblasts

21 January 2018

1 reference

The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy

21 January 2018

1 reference

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

1 reference

An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure

21 January 2018

1 reference

The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice

21 January 2018

1 reference

Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis

21 January 2018

1 reference

Antimicrobial mechanisms of phagocytes and bacterial evasion strategies

21 January 2018

1 reference

Bacterial invasion: the paradigms of enteroinvasive pathogens

21 January 2018

1 reference

Autophagy defends cells against invading group A Streptococcus

21 January 2018

1 reference

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

21 January 2018

1 reference

Escape of intracellular Shigella from autophagy

21 January 2018

1 reference

Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole.

21 January 2018

1 reference

Bacteria-autophagy interplay: a battle for survival

21 January 2018

1 reference

Ubiquitin and ubiquitin-like proteins as multifunctional signals

21 January 2018

1 reference

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

21 January 2018

1 reference

Ubiquitination-mediated autophagy against invading bacteria

21 January 2018

1 reference

Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity

21 January 2018

1 reference

The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella Typhimurium

21 January 2018

1 reference

The ubiquitin ligase parkin mediates resistance to intracellular pathogens

21 January 2018

1 reference

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

Artificial induction of autophagy around polystyrene beads in nonphagocytic cells.

21 January 2018

1 reference

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

21 January 2018

1 reference

Spatiotemporally controlled induction of autophagy-mediated lysosome turnover

21 January 2018

1 reference

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

21 January 2018

1 reference

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

21 January 2018

1 reference

Viruses and the autophagy machinery

21 January 2018

1 reference

Autophagy and selective deployment of Atg proteins in antiviral defense

21 January 2018

1 reference

Autophagy protects against Sindbis virus infection of the central nervous system

21 January 2018

1 reference

Image-based genome-wide siRNA screen identifies selective autophagy factors

21 January 2018

1 reference

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

21 January 2018

1 reference

Identification of a candidate therapeutic autophagy-inducing peptide

21 January 2018

1 reference

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

21 January 2018

1 reference

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

21 January 2018

1 reference

Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes

21 January 2018

1 reference

Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle

21 January 2018

1 reference

Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens

21 January 2018

1 reference

Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma

21 January 2018

1 reference

Role of microtubules in extracellular release of poliovirus

21 January 2018

1 reference

Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers

21 January 2018

1 reference

A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion

21 January 2018

1 reference

The roles of TLRs, RLRs and NLRs in pathogen recognition

21 January 2018

1 reference

Autophagy in infection, inflammation, and immunity

21 January 2018

1 reference

Activation and regulation of the inflammasomes

21 January 2018

1 reference

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

1 reference

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

21 January 2018

1 reference

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

21 January 2018

1 reference

A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3.

21 January 2018

1 reference

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

21 January 2018

1 reference

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

21 January 2018

1 reference

A role for mitochondria in NLRP3 inflammasome activation

21 January 2018

1 reference

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

21 January 2018

1 reference

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

21 January 2018

1 reference

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

21 January 2018

1 reference

Autophagy links inflammasomes to atherosclerotic progression.

21 January 2018

1 reference

Atg16L1 deficiency confers protection from uropathogenic Escherichia coli infection in vivo

21 January 2018

1 reference

Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules

21 January 2018

1 reference

Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer

21 January 2018

1 reference

Anti-inflammatory and antiatherogenic effects of the NLRP3 inflammasome inhibitor arglabin in ApoE2.Ki mice fed a high-fat diet

21 January 2018

1 reference

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

21 January 2018

1 reference

Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation

21 January 2018

1 reference

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

21 January 2018

1 reference

Mechanisms and functions of inflammasomes

21 January 2018

1 reference

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

21 January 2018

1 reference

Inflammasome-independent regulation of IL-1-family cytokines

21 January 2018

1 reference

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

21 January 2018

1 reference

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

1 reference

Viral RNA detection by RIG-I-like receptors

21 January 2018

1 reference

The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling

21 January 2018

1 reference

Autophagy-dependent viral recognition by plasmacytoid dendritic cells

21 January 2018

1 reference

Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling

21 January 2018

1 reference

The Atg5 Atg12 conjugate associates with innate antiviral immune responses

21 January 2018

1 reference

The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

21 January 2018

1 reference

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

21 January 2018

1 reference

Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling

21 January 2018

1 reference

Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses

21 January 2018

1 reference

Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway

21 January 2018

1 reference

A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis.

21 January 2018

1 reference

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis

21 January 2018

1 reference

Pathways of antigen processing

21 January 2018

1 reference

Checking the garbage bin for problems in the house, or how autophagy assists in antigen presentation to the immune system

21 January 2018

1 reference

Endogenous MHC class II processing of a viral nuclear antigen after autophagy.

21 January 2018

1 reference

Nuclear location of an endogenously expressed antigen, EBNA1, restricts access to macroautophagy and the range of CD4 epitope display.

21 January 2018

1 reference

Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells

21 January 2018

1 reference

Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes

21 January 2018

1 reference

Regulation of SIV antigen-specific CD4+ T cellular immunity via autophagosome-mediated MHC II molecule-targeting antigen presentation in mice

21 January 2018

1 reference

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance

21 January 2018

1 reference

Autophagic compartments gain access to the MHC class II compartments in thymic epithelium.

21 January 2018

1 reference

Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance

21 January 2018

1 reference

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

21 January 2018

1 reference

Autophagy proteins stabilize pathogen-containing phagosomes for prolonged MHC II antigen processing.

21 January 2018

1 reference

Dectin-1-triggered recruitment of light chain 3 protein to phagosomes facilitates major histocompatibility complex class II presentation of fungal-derived antigens.

21 January 2018

1 reference

Cutting edge: FYCO1 recruitment to dectin-1 phagosomes is accelerated by light chain 3 protein and regulates phagosome maturation and reactive oxygen production

21 January 2018

1 reference

In vivo requirement for Atg5 in antigen presentation by dendritic cells

21 January 2018

1 reference

Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells

21 January 2018

1 reference

The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens

21 January 2018

1 reference

Plasma cells require autophagy for sustainable immunoglobulin production.

21 January 2018

1 reference

Autophagy inhibition promotes defective neosynthesized proteins storage in ALIS, and induces redirection toward proteasome processing and MHCI-restricted presentation.

21 January 2018

1 reference

Ordered organelle degradation during starvation-induced autophagy

21 January 2018

1 reference

Degradation of proteasomes by lysosomes in rat liver.

21 January 2018

1 reference

Autophagic Degradation of the 26S Proteasome Is Mediated by the Dual ATG8/Ubiquitin Receptor RPN10 in Arabidopsis

21 January 2018

1 reference

Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

21 January 2018

1 reference

Exogenous, TAP-independent lysosomal presentation of a respiratory syncytial virus CTL epitope

21 January 2018

1 reference

Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses

21 January 2018

1 reference

Amphisomal route of MHC class I cross-presentation in bacteria-infected dendritic cells

21 January 2018

1 reference

CD4(+) T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease

21 January 2018

1 reference

Unconventional secretion of Acb1 is mediated by autophagosomes.

21 January 2018

1 reference

Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation.

21 January 2018

1 reference

Autophagy regulates selective HMGB1 release in tumor cells that are destined to die.

21 January 2018

1 reference

Molecular mechanisms of ATP secretion during immunogenic cell death

21 January 2018

1 reference

Autophagy proteins regulate the secretory component of osteoclastic bone resorption

21 January 2018

1 reference

Subversion of cellular autophagosomal machinery by RNA viruses

21 January 2018

1 reference

Macroautophagy Proteins Assist Epstein Barr Virus Production and Get Incorporated Into the Virus Particles.

21 January 2018

1 reference

Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells

21 January 2018

1 reference

Efficient cross-presentation depends on autophagy in tumor cells

21 January 2018

1 reference

Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory T cells

21 January 2018

1 reference

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

21 January 2018

1 reference

A critical role for the autophagy gene Atg5 in T cell survival and proliferation

21 January 2018

1 reference

A role for autophagic protein beclin 1 early in lymphocyte development

21 January 2018

1 reference

Autophagy is essential for mitochondrial clearance in mature T lymphocytes

21 January 2018

1 reference

Transient receptor potential vanilloid 1 activation induces autophagy in thymocytes through ROS-regulated AMPK and Atg4C pathways.

21 January 2018

1 reference

Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis.

21 January 2018

1 reference

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells

21 January 2018

1 reference

Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes

21 January 2018

1 reference

Impaired autophagy, defective T cell homeostasis, and a wasting syndrome in mice with a T cell-specific deletion of Vps34.

21 January 2018

1 reference

Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery

21 January 2018

1 reference

Autophagy is a critical regulator of memory CD8(+) T cell formation

21 January 2018

1 reference

Autophagy is essential for effector CD8(+) T cell survival and memory formation

21 January 2018

1 reference

ATG5 regulates plasma cell differentiation

21 January 2018

1 reference

A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells

21 January 2018

1 reference

Essential role for autophagy in the maintenance of immunological memory against influenza infection

21 January 2018

1 reference

Intestinal epithelial autophagy is essential for host defense against invasive bacteria

21 January 2018

1 reference

Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection

21 January 2018

1 reference

Autophagic control of listeria through intracellular innate immune recognition in drosophila

21 January 2018

1 reference

Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus

21 January 2018

1 reference

21 January 2018

1 reference

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

21 January 2018

1 reference

A deficiency in the autophagy gene Atg16L1 enhances resistance to enteric bacterial infection

21 January 2018

1 reference

Toll-like receptor 4 is a sensor for autophagy associated with innate immunity

21 January 2018

1 reference

Toll-like receptors control autophagy.

21 January 2018

1 reference

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

21 January 2018

1 reference

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

21 January 2018

1 reference

NLRP4 negatively regulates autophagic processes through an association with beclin1.

21 January 2018

1 reference

Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection

21 January 2018

1 reference

Endogenous HMGB1 regulates autophagy

21 January 2018

1 reference

Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4.

21 January 2018

1 reference

Human IRGM induces autophagy to eliminate intracellular mycobacteria

21 January 2018

1 reference

TNF-alpha induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells

21 January 2018

1 reference

p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathways

21 January 2018

1 reference

TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation

21 January 2018

1 reference

T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis.

21 January 2018

1 reference

Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity

21 January 2018

1 reference

Autophagy limits Listeria monocytogenes intracellular growth in the early phase of primary infection

21 January 2018

1 reference

12 December 2020

Autophagy mediates transporter associated with antigen processing-independent presentation of viral epitopes through MHC class I pathway

1 reference

12 December 2020

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein

1 reference

12 December 2020

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2

1 reference

12 December 2020

The proximal tubule cell in experimental hydronephrosis

1 reference

12 December 2020

Autophagy facilitates major histocompatibility complex class I expression induced by IFN-γ in B16 melanoma cells

1 reference

12 December 2020

The autophagy gene ATG5 plays an essential role in B lymphocyte development

1 reference

12 December 2020

Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy

1 reference

12 December 2020

Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance

1 reference

12 December 2020

Cellular differentiation in the kidneys of newborn mice studies with the electron microscope.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.3273

1 reference

4 September 2017

1 reference