Endocytic membrane trafficking and neurodegenerative disease (Q38684233)

5 September 2017

Endocytic membrane trafficking and neurodegenerative disease (English)

1 reference

5 September 2017

1 reference

2

Edward A Fon

1 reference

5 September 2017

Andrea M A Schreij

1

1 reference

PubMed ID

26721251

5 September 2017

Peter S McPherson

series ordinal

3

1 reference

PubMed ID

26721251

5 September 2017

language of work or name

1 reference

31 December 2015

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Cellular and Molecular Life Sciences

5 September 2017

1 reference

5 September 2017

73

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5 September 2017

1529-1545

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5 September 2017

8

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https://scigraph.springernature.com/pub.10.1007/s00018-015-2105-x

5 September 2017

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cites work

Genetics of neurodegenerative diseases: insights from high-throughput resequencing

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Parkinson's disease: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Focality, stochasticity and neuroanatomic propagation in ALS pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Ageing, neurodegeneration and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Unfolding the role of protein misfolding in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Strumpellin is a novel valosin-containing protein binding partner linking hereditary spastic paraplegia to protein aggregation diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Endosome maturation, transport and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mannose-6-phosphate pathway: a review on its role in lysosomal function and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Regulated portals of entry into the cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Cell biology of the presynaptic terminal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Assembly units of clathrin coats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Molecular architecture and functional model of the endocytic AP2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The first five seconds in the life of a clathrin-coated pit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

AP2 controls clathrin polymerization with a membrane-activated switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

An endophilin-dynamin complex promotes budding of clathrin-coated vesicles during synaptic vesicle recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Essential role of phosphoinositide metabolism in synaptic vesicle recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A presynaptic inositol-5-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Auxilin, a newly identified clathrin-associated protein in coated vesicles from bovine brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset Parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A deleterious mutation in DNAJC6 encoding the neuronal-specific clathrin-uncoating co-chaperone auxilin, is associated with juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The yeast synaptojanin-like proteins control the cellular distribution of phosphatidylinositol (4,5)-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Phosphoinositides in cell regulation and membrane dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Endocytosis and clathrin-uncoating defects at synapses of auxilin knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Multiple roles of auxilin and hsc70 in clathrin-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

GWAS-linked GAK locus in Parkinson's disease in Han Chinese and meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Reaffirmation of GAK, but not HLA-DRA, as a Parkinson's disease susceptibility gene in a Taiwanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

rab5 controls early endosome fusion in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Rab GTPases as coordinators of vesicle traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The Rab5 effector EEA1 is a core component of endosome docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The first ALS2 missense mutation associated with JPLS reveals new aspects of alsin biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Alsin/Rac1 signaling controls survival and growth of spinal motoneurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Endosome acidification and receptor trafficking: bafilomycin A1 slows receptor externalization by a mechanism involving the receptor's internalization motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Prorenin receptor is essential for podocyte autophagy and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Hrs recruits clathrin to early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

VHS domain -- a longshoreman of vesicle lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Endofin recruits clathrin to early endosomes via TOM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Parkinson's disease: the LRRK2-G2019S mutation: opening a novel era in Parkinson's disease genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Rab conversion as a mechanism of progression from early to late endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

An early endosome regulator, Rab5b, is an LRRK2 kinase substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

ESCRT complexes and the biogenesis of multivesicular bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The emerging shape of the ESCRT machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Multivesicular bodies: co-ordinated progression to maturity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Molecular mechanisms of late endosome morphology, identity and sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Hrs- and CD63-dependent competing mechanisms make different sized endosomal intraluminal vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A concentric circle model of multivesicular body cargo sorting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The UIM domain of Hrs couples receptor sorting to vesicle formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Ubiquitin recognition by the human TSG101 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Ent5p is required with Ent3p and Vps27p for ubiquitin-dependent protein sorting into the multivesicular body.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A founder mutation in Vps37A causes autosomal recessive complex hereditary spastic paraparesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

ATPase-deficient hVPS4 impairs formation of internal endosomal vesicles and stabilizes bilayered clathrin coats on endosomal vacuoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Spastin, a new AAA protein, is altered in the most frequent form of autosomal dominant spastic paraplegia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Hereditary spastic paraplegia caused by mutations in the SPG4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

An ESCRT-spastin interaction promotes fission of recycling tubules from the endosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Troyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Exosomes: small vesicles participating in intercellular communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

ExoCarta: A compendium of exosomal proteins and RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

ATP13A2/PARK9 regulates secretion of exosomes and α-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Recent advances in retromer biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Recruitment of the endosomal WASH complex is mediated by the extended 'tail' of Fam21 binding to the retromer protein Vps35

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

VPS35 mutations in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The Vps35 D620N mutation linked to Parkinson's disease disrupts the cargo sorting function of retromer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

DNAJC13 mutations in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The DnaJ-domain protein RME-8 functions in endosomal trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Regulation of endosomal clathrin and retromer-mediated endosome to Golgi retrograde transport by the J-domain protein RME-8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

RME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mutations in the KIAA0196 gene at the SPG8 locus cause hereditary spastic paraplegia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The hereditary spastic paraplegia protein strumpellin: characterisation in neurons and of the effect of disease mutations on WASH complex assembly and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Transport according to GARP: receiving retrograde cargo at the trans-Golgi network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

An hereditary motor neurone disease with progressive denervation of muscle in the mouse: the mutant 'wobbler'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Loss of vps54 function leads to vesicle traffic impairment, protein mis-sorting and embryonic lethality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Endosomal accumulation of APP in wobbler motor neurons reflects impaired vesicle trafficking: implications for human motor neuron disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Association of sequence alterations in the putative promoter of RAB7L1 with a reduced parkinson disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A role of Rab29 in the integrity of the trans-Golgi network and retrograde trafficking of mannose-6-phosphate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Modelling C9ORF72 hexanucleotide repeat expansion in amyotrophic lateral sclerosis and frontotemporal dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The product of C9orf72, a gene strongly implicated in neurodegeneration, is structurally related to DENN Rab-GEFs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

DENN domain proteins: regulators of Rab GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Pathogenic effects of novel mutations in the P-type ATPase ATP13A2 (PARK9) causing Kufor-Rakeb syndrome, a form of early-onset parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Deficiency of ATP13A2 leads to lysosomal dysfunction, α-synuclein accumulation, and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The fifth adaptor protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Identification of the SPG15 gene, encoding spastizin, as a frequent cause of complicated autosomal-recessive spastic paraplegia, including Kjellin syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A hereditary spastic paraplegia mouse model supports a role of ZFYVE26/SPASTIZIN for the endolysosomal system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Lysosomal abnormalities in hereditary spastic paraplegia types SPG15 and SPG11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Parkinsonism among Gaucher disease carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Glucocerebrosidase mutations in subjects with parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

A vesicular transport pathway shuttles cargo from mitochondria to lysosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Autophagy: renovation of cells and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mutations of optineurin in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Adult-onset primary open-angle glaucoma caused by mutations in optineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Differential involvement of optineurin in amyotrophic lateral sclerosis with or without SOD1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Brain connectivity in neurodegenerative diseases--from phenotype to proteinopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Membrane Transport: A Coat for Ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-2105-X

Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control

21 January 2018

1 reference

12 December 2020

VPS54 genetic analysis in ALS Italian cohort

1 reference

12 December 2020

Evaluation of the Golgi trafficking protein VPS54 (wobbler) as a candidate for ALS.

1 reference

12 December 2020

Cellular pathology of lysosomal storage disorders.

1 reference

12 December 2020

The oculocerebrorenal syndrome gene product is a 105-kD protein localized to the Golgi complex

1 reference

12 December 2020

Recruitment dynamics of GAK and auxilin to clathrin-coated pits during endocytosis

1 reference

12 December 2020

In vivo evidence of pathogenicity of VPS35 mutations in the Drosophila

1 reference

12 December 2020

Optineurin: The autophagy connection

1 reference

12 December 2020

Risk factors for amyotrophic lateral sclerosis

1 reference

12 December 2020

Bafilomycin A1 treatment retards transferrin receptor recycling more than bulk membrane recycling

1 reference

12 December 2020

SPG20 is mutated in Troyer syndrome, an hereditary spastic paraplegia.

1 reference

12 December 2020

Rab9 functions in transport between late endosomes and the trans Golgi network

1 reference

12 December 2020

Protein organization in clathrin trimers

1 reference

12 December 2020

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis.

1 reference

12 December 2020

10.1007/S00018-015-2105-X

Identifiers

DOI

1 reference

5 September 2017

1 reference

PubMed ID

26721251