Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges (Q38699332)

5 July 2018

title

Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges (English)

1 reference

5 July 2018

MAM domain containing glycosylphosphatidylinositol anchor 1

main subject

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regulation of presynapse assembly

GOA release 2020-03-11

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GOA release 2020-03-11

5

Mischa Machius

1 reference

5 July 2018

Shanti Pal Gangwar

1

1 reference

5 July 2018

Xiaoying Zhong

2

1 reference

5 July 2018

Suchithra Seshadrinathan

3

1 reference

5 July 2018

Hui Chen

4

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5 July 2018

Gabby Rudenko

6

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5 July 2018

language of work or name

English

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publication date

1 June 2017

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5 July 2018

published in

Neuron

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5 July 2018

volume

94

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5 July 2018

issue

6

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5 July 2018

page(s)

1132-1141.e4

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5 July 2018

Dynamic Control of Synaptic Adhesion and Organizing Molecules in Synaptic Plasticity.

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MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development

10 July 2018

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Dimerization of postsynaptic neuroligin drives synaptic assembly via transsynaptic clustering of neurexin

10 July 2018

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IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons

10 July 2018

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Homophilic Adhesion Mechanism of Neurofascin, a Member of the L1 Family of Neural Cell Adhesion Molecules

10 July 2018

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Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions

10 July 2018

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Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons

10 July 2018

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Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation

10 July 2018

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Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes

10 July 2018

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Mutational analysis of the neurexin/neuroligin complex reveals essential and regulatory components

10 July 2018

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10 July 2018

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10 July 2018

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Structures of neuroligin-1 and the neuroligin-1/neurexin-1 beta complex reveal specific protein-protein and protein-Ca2+ interactions

10 July 2018

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10 July 2018

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10 July 2018

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10 July 2018

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10 July 2018

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10 July 2018

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Radial migration of superficial layer cortical neurons controlled by novel Ig cell adhesion molecule MDGA1

10 July 2018

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10 July 2018

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A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins

10 July 2018

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Neuroligins mediate excitatory and inhibitory synapse formation: involvement of PSD-95 and neurexin-1beta in neuroligin-induced synaptic specificity.

10 July 2018

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Neuroligin 2 is exclusively localized to inhibitory synapses

10 July 2018

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10 July 2018

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10 July 2018

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10 July 2018

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10 July 2018

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10 July 2018

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Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2.

10 July 2018

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Targeted combinatorial alternative splicing generates brain region-specific repertoires of neurexins.

31 August 2018

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Engineering disulfide bonds within an antibody.

31 August 2018

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Specific trans-synaptic interaction with inhibitory interneuronal neurexin underlies differential ability of neuroligins to induce functional inhibitory synapses

31 August 2018

1 reference

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The MDGA1 gene confers risk to schizophrenia and bipolar disorder

31 August 2018

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Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene

31 August 2018

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Alternative splicing controls selective trans-synaptic interactions of the neuroligin-neurexin complex.

31 August 2018

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10.1016/J.NEURON.2017.06.009

31 August 2018

Identifiers

DOI

1 reference

5 July 2018

PMC publication ID

5745067

1 reference

5 July 2018

PubMed publication ID

28641112

1 reference

5 July 2018