Interleukin-11: A Multifunctional Cytokine with Intrinsically Disordered Regions (Q38873802)

7 September 2017

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title

Interleukin-11: A Multifunctional Cytokine with Intrinsically Disordered Regions (English)

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7 September 2017

2

Vladimir N Uversky

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7 September 2017

Eugene A Permyakov

1

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7 September 2017

Sergei E Permyakov

series ordinal

3

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7 September 2017

publication date

22 June 2016

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Cell Biochemistry and Biophysics

7 September 2017

published in

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7 September 2017

volume

74

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7 September 2017

issue

3

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7 September 2017

page(s)

285-296

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Cytokines, inflammation, and pain

7 September 2017

cites work

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https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Gp130 and the interleukin-6 family of cytokines

21 January 2018

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Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically

21 January 2018

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Introducing protein intrinsic disorder

21 January 2018

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Exploiting heterogeneous sequence properties improves prediction of protein disorder.

21 January 2018

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Predicting intrinsic disorder from amino acid sequence

21 January 2018

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Intrinsically disordered protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

PONDR-FIT: a meta-predictor of intrinsically disordered amino acids

21 January 2018

1 reference

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ANCHOR: web server for predicting protein binding regions in disordered proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Prediction of protein binding regions in disordered proteins

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

The pairwise energy content estimated from amino acid composition discriminates between folded and intrinsically unstructured proteins.

21 January 2018

1 reference

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The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

The dynamics of signal triggering in a gp130-receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Interleukin-11 signals through the formation of a hexameric receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Modular organization of Interleukin-6 and Interleukin-11 α-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Mediation of interleukin-11-dependent biological responses by a soluble form of the interleukin-11 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Proteolytic Cleavage Governs Interleukin-11 Trans-signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

STAT3-Activating Cytokines: A Therapeutic Opportunity for Inflammatory Bowel Disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Randomized, double blind controlled trial of subcutaneous recombinant human interleukin-11 versus prednisolone in active Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Identification of three distinct receptor binding sites of murine interleukin-11

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Functional characterization of W147A: a high-affinity interleukin-11 antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

1.9 A crystal structure of interleukin 6: implications for a novel mode of receptor dimerization and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

A method for simultaneous alignment of multiple protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Inference of macromolecular assemblies from crystalline state

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Target selectivity in EF-hand calcium binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Molecular mechanisms of S100-target protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Significance of S100P as a biomarker in diagnosis, prognosis and therapy of opisthorchiasis-associated cholangiocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

S100P, a novel Ca2+ -binding protein from human placenta. cDNA cloning, recombinant protein expression and Ca2+ binding properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

NMR structure of the Apo-S100P protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

S100P, a peculiar member of S100 family of calcium-binding proteins implicated in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

S100P: a novel therapeutic target for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

High-affinity interaction between interleukin-11 and S100P protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Interleukin-11 binds specific EF-hand proteins via their conserved structural motifs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Two structural motifs within canonical EF-hand calcium-binding domains identify five different classes of calcium buffers and sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Interleukin-6 and interleukin-11: same same but different

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Intrinsic disorder in S100 proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Molecular structure and target recognition of neuronal calcium sensor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Structural diversity of neuronal calcium sensor proteins and insights for activation of retinal guanylyl cyclase by GCAP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Calmodulin levels in blood cells as a potential biomarker of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Quantitative determinations of calmodulin in the supernatant and particulate fractions of mammalian tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Direct modulation of calmodulin targets by the neuronal calcium sensor NCS-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Regulatory modes of rod outer segment membrane guanylate cyclase differ in catalytic efficiency and Ca(2+)-sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Necrosis: a specific form of programmed cell death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Free and bound intracellular calmodulin measurements in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Developmental expression of NCS-1 (frequenin), a regulator of Kv4 K+ channels, in mouse heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

S100B Protein, A Damage-Associated Molecular Pattern Protein in the Brain and Heart, and Beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Stroke biomarkers: progress and challenges for diagnosis, prognosis, differentiation, and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Light-induced disulfide dimerization of recoverin under ex vivo and in vivo conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

IL-11 expression in retinal and corneal cells is regulated by interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Immunotherapeutic strategies in autoimmune uveitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

More than a sidekick: the IL-6 family cytokine IL-11 links inflammation to cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Recombinant human interleukin-11 (IL-11) is a protective factor in severe sepsis with thrombocytopenia: A case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Improvement of biological and pharmacokinetic features of human interleukin-11 by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Selective anti-inflammatory action of interleukin-11 in murine Lyme disease: arthritis decreases while carditis persists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Comparative study of serum and synovial fluid interleukin-11 levels in patients with various arthritides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

New generation contraceptives: interleukin 11 family cytokines as non-steroidal contraceptive targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Interleukin-11 alters placentation and causes preeclampsia features in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Therapeutic activation of signal transducer and activator of transcription 3 by interleukin-11 ameliorates cardiac fibrosis after myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Molecular pathways: IL11 as a tumor-promoting cytokine-translational implications for cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Targeting IL-11 signaling in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

High expression of interleukin-11 is an independent indicator of poor prognosis in clear-cell renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

Targeting Interleukin-11 Receptor-α Impairs Human Endometrial Cancer Cell Proliferation and Invasion In Vitro and Reduces Tumor Growth and Metastasis In Vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-016-0752-7

10.1007/S12013-016-0752-7

21 January 2018

Identifiers

DOI

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Dimensions Publication ID

7 September 2017

1031041346

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Fatcat ID

release_7zp4gv2r65hbrcaf2v7i47k7ne

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Fatcat

https://api.fatcat.wiki/v0/release/7zp4gv2r65hbrcaf2v7i47k7ne

mapped directly with Wikidata item

24 November 2022

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