Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways (Q38989588)

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English	Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

8 September 2017

Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways (English)

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Europe PubMed Central

PMC publication ID

8 September 2017

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based on heuristic

inferred from title

prostate cancer

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based on heuristic

inferred from title

1

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24882580%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Philip C. Trackman

4

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6 June 2020

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G B Ozdener

2

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6 June 2020

G E Sonenshein

3

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6 June 2020

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2 June 2014

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8 September 2017

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6 June 2020

34

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6 June 2020

15

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6 June 2020

1928-1937

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6 June 2020

Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide

1 reference

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9 September 2017

Lysyl oxidase is downregulated by the EWS/FLI1 oncoprotein and its propeptide domain displays tumor supressor activities in Ewing sarcoma cells

1 reference

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9 September 2017

The ATM protein kinase: regulating the cellular response to genotoxic stress, and more

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9 September 2017

Systematic review of hypofractionated radiation therapy for prostate cancer

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9 September 2017

DNA repair dysregulation from cancer driver to therapeutic target

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9 September 2017

New strategies against prostate cancer--Pt(II)-based chemotherapy

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9 September 2017

The rationale for targeting the LOX family in cancer

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9 September 2017

Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts

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9 September 2017

The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation

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9 September 2017

The lysyl oxidase propeptide interacts with the receptor-type protein tyrosine phosphatase kappa and inhibits β-catenin transcriptional activity in lung cancer cells

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9 September 2017

The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells

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9 September 2017

ATM protein kinase: the linchpin of cellular defenses to stress

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9 September 2017

Mechanisms of resistance to epidermal growth factor receptor tyrosine kinase inhibitors in patients with advanced non-small-cell lung cancer: clinical and molecular considerations

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9 September 2017

The effect of a DNA repair gene on cellular invasiveness: XRCC3 over-expression in breast cancer cells

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9 September 2017

Tumor Suppressor CHK2: Regulator of DNA Damage Response and Mediator of Chromosomal Stability

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H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy.

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9 September 2017

Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis

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9 September 2017

A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer

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9 September 2017

Cell cycle kinases as therapeutic targets for cancer

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9 September 2017

BMP2 is essential for post natal osteogenesis but not for recruitment of osteogenic stem cells

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9 September 2017

The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells

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9 September 2017

Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

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9 September 2017

Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation

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9 September 2017

Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation

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9 September 2017

Triglyceride-rich lipoprotein lipolysis increases aggregation of endothelial cell membrane microdomains and produces reactive oxygen species

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9 September 2017

Overexpression of DNA repair genes is associated with metastasis: a new hypothesis

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9 September 2017

The Mre11 complex mediates the S-phase checkpoint through an interaction with replication protein A.

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9 September 2017

Clonogenic assay of cells in vitro.

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9 September 2017

Radiation and new molecular agents part I: targeting ATM-ATR checkpoints, DNA repair, and the proteasome

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9 September 2017

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

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9 September 2017

Cell cycle checkpoints and their impact on anticancer therapeutic strategies

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9 September 2017

Quantitative Comparison of Long-wavelength Alexa Fluor Dyes to Cy Dyes: Fluorescence of the Dyes and Their Bioconjugates

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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9 September 2017

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

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9 September 2017

Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase

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9 September 2017

Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures

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9 September 2017

DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways

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9 September 2017

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

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9 September 2017

Complex formation and functional versatility of Mre11 of budding yeast in recombination

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9 September 2017

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

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Metalloproteinase Activity Secreted by Fibrogenic Cells in the Processing of Prolysyl Oxidase

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9 September 2017

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9 September 2017

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9 September 2017

Lysyl oxidase propeptide inhibits prostate cancer cell growth by mechanisms that target FGF-2-cell binding and signaling.

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14 September 2017

Rationale, conduct, and outcome using hypofractionated radiotherapy in prostate cancer

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14 September 2017

Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254378

14 September 2017

Clonogenic cell survival assay

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14 September 2017

The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells.

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14 September 2017

Autocrine growth factor regulation of lysyl oxidase expression in transformed fibroblasts

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14 September 2017

Characterization of recombinant lysyl oxidase propeptide

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17 June 2018

Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation

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17 June 2018

Expression of the lysyl oxidase propeptide in hepatocellular carcinoma and its clinical relevance

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21 August 2018

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21 August 2018

The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer.

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21 August 2018

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21 August 2018

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1 reference

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21 August 2018

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21 August 2018

Expression of Gene rrg Is Associated with Reversion of NIH 3Tt3 Transformed by LTR-c-H- ras

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21 January 2018

Lysyl oxidase and rrg messenger RNA.

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21 January 2018

High expression of DNA repair pathways is associated with metastasis in melanoma patients

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31 March 2020

Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2

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Measurement of apoptosis by DNA fragmentation

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metalloproteinase activity secreted by fibrogenic cells in the processing of prolysyl oxidase. Potential role of procollagen C-proteinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24882580

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1038/ONC.2014.147

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24882580%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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24 November 2022

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24882580%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24882580%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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