Induced pluripotent stem cell technology: a decade of progress (Q39040578)

30 June 2019

title

Induced pluripotent stem cell technology: a decade of progress (English)

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30 June 2019

4

Shinya Yamanaka

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8 September 2017

3

Joseph C Wu

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30 June 2019

author name string

Yanhong Shi

series ordinal

1

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30 June 2019

Haruhisa Inoue

series ordinal

2

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30 June 2019

publication date

16 December 2016

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30 June 2019

Nature Reviews Drug Discovery

published in

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30 June 2019

volume

16

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30 June 2019

page(s)

115-130

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30 June 2019

issue

2

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30 June 2019

https://scigraph.springernature.com/pub.10.1038/nrd.2016.245

exact match

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Modeling Human Severe Combined Immunodeficiency and Correction by CRISPR/Cas9-Enhanced Gene Targeting.

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Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9.

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Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs

21 January 2018

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Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

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Induced pluripotent stem cells from a spinal muscular atrophy patient

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Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

21 January 2018

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Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency

21 January 2018

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LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

21 January 2018

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Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease

21 January 2018

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Human iPSC-based modeling of late-onset disease via progerin-induced aging

21 January 2018

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Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

21 January 2018

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Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration.

21 January 2018

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ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks

21 January 2018

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Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience

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Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.

21 January 2018

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Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro

21 January 2018

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Astroglia induce neurogenesis from adult neural stem cells

21 January 2018

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Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes.

21 January 2018

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Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness

21 January 2018

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Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression

21 January 2018

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Modeling familial Alzheimer's disease with induced pluripotent stem cells

21 January 2018

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The presenilin-1 ΔE9 mutation results in reduced γ-secretase activity, but not total loss of PS1 function, in isogenic human stem cells

21 January 2018

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APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.

21 January 2018

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Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease

21 January 2018

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Stem cell derived basal forebrain cholinergic neurons from Alzheimer's disease patients are more susceptible to cell death

21 January 2018

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The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons

21 January 2018

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Induced pluripotent stem cells from familial Alzheimer's disease patients differentiate into mature neurons with amyloidogenic properties

21 January 2018

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Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers

21 January 2018

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Elucidating molecular phenotypes caused by the SORL1 Alzheimer's disease genetic risk factor using human induced pluripotent stem cells

21 January 2018

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Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer's disease donor as a model for investigating AD-associated gene regulatory networks

21 January 2018

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APP metabolism regulates tau proteostasis in human cerebral cortex neurons

21 January 2018

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Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes.

21 January 2018

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Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells

21 January 2018

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Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

21 January 2018

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Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue

21 January 2018

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Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells

21 January 2018

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Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.

21 January 2018

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Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression

21 January 2018

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Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription

21 January 2018

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Physiological characterisation of human iPS-derived dopaminergic neurons

21 January 2018

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iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis.

21 January 2018

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iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson's disease

21 January 2018

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Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation

21 January 2018

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Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.

21 January 2018

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Parkin mutations reduce the complexity of neuronal processes in iPSC-derived human neurons

21 January 2018

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Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines

21 January 2018

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A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism

21 January 2018

1 reference

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Modelling schizophrenia using human induced pluripotent stem cells

21 January 2018

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RNA-Seq of human neurons derived from iPS cells reveals candidate long non-coding RNAs involved in neurogenesis and neuropsychiatric disorders

21 January 2018

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Synaptic dysregulation in a human iPS cell model of mental disorders

21 January 2018

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The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model

21 January 2018

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Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia

21 January 2018

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Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

21 January 2018

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Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity

21 January 2018

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Functional Implications of miR-19 in the Migration of Newborn Neurons in the Adult Brain.

21 January 2018

1 reference

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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

21 January 2018

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Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

21 January 2018

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Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

21 January 2018

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Organogenesis in a dish: modeling development and disease using organoid technologies

21 January 2018

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Modelling human development and disease in pluripotent stem-cell-derived gastric organoids

21 January 2018

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Vascularized and functional human liver from an iPSC-derived organ bud transplant.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

21 January 2018

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Directed differentiation of cholangiocytes from human pluripotent stem cells.

21 January 2018

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In vitro generation of human pluripotent stem cell derived lung organoids

21 January 2018

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Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

An in vivo model of human small intestine using pluripotent stem cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Swimming muscles power suction feeding in largemouth bass

21 January 2018

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FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

21 January 2018

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Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

21 January 2018

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Zika virus impairs growth in human neurospheres and brain organoids

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

CPAP promotes timely cilium disassembly to maintain neural progenitor pool

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size

21 January 2018

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Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

21 January 2018

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Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies

21 January 2018

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Organoids as an in vitro model of human development and disease.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Cerebral organoids model human brain development and microcephaly

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Developing predictive assays: the phenotypic screening "rule of 3".

21 January 2018

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iPS cells: a game changer for future medicine

21 January 2018

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Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Drug screening for ALS using patient-specific induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

A cellular model for sporadic ALS using patient-derived induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Human secreted tau increases amyloid-beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Prevention of β-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Transdifferentiation via transcription factors or microRNAs: Current status and perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Reprogramming cell fates: insights from combinatorial approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Early pathogenesis of Duchenne muscular dystrophy modelled in patient-derived human induced pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

The use of induced pluripotent stem cells in drug development

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Statin treatment rescues FGFR3 skeletal dysplasia phenotypes.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

From Dish to Bedside: Lessons Learned While Translating Findings from a Stem Cell Model of Disease to a Clinical Trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

The $2.6 billion pill--methodologic and policy considerations

21 January 2018

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Innovation in the pharmaceutical industry: New estimates of R&D costs

21 January 2018

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Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Predicting drug-induced changes in QT interval and arrhythmias: QT-shortening drugs point to gaps in the ICHS7B Guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes

21 January 2018

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Evolution of strategies to improve preclinical cardiac safety testing

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Comparison of electrophysiological data from human-induced pluripotent stem cell-derived cardiomyocytes to functional preclinical safety assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Proarrhythmia Risk Assessment in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Using the Maestro MEA Platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

In vitro differentiation of embryonic stem cells into hepatocyte-like cells identified by cellular uptake of indocyanine green

21 January 2018

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Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Human pluripotent stem cell-derived neural constructs for predicting neural toxicity

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2016.245

Embryonic stem cell lines derived from human blastocysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Translation of Human-Induced Pluripotent Stem Cells: From Clinical Trial in a Dish to Precision Medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Hurdles to clinical translation of human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Genetic and epigenetic stability of human pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Inhibition of pluripotent stem cell-derived teratoma formation by small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Potential Strategies to Address the Major Clinical Barriers Facing Stem Cell Regenerative Therapy for Cardiovascular Disease: A Review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Immunosuppression by embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Characterization of the expression of MHC proteins in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Pluripotent stem cells: immune to the immune system?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

10 Questions: Clinical Outlook for iPSCs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Do human leukocyte antigen-typed cellular therapeutics based on induced pluripotent stem cells make commercial sense?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Strategy for the creation of clinical grade hESC line banks that HLA-match a target population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

From Genomics to Gene Therapy: Induced Pluripotent Stem Cells Meet Genome Editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Genome editing in pluripotent stem cells: research and therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Induced Pluripotency and Gene Editing in Disease Modelling: Perspectives and Challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

iPSCs: A Minireview from Bench to Bed, including Organoids and the CRISPR System

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Single-cell gene expression profiles define self-renewing, pluripotent, and lineage primed states of human pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Variation in the safety of induced pluripotent stem cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

A decade of transcription factor-mediated reprogramming to pluripotency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Next-generation regenerative medicine: organogenesis from stem cells in 3D culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Self-formation of optic cups and storable stratified neural retina from human ESCs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Self-organization of polarized cerebellar tissue in 3D culture of human pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Organoid Models of Human Gastrointestinal Development and Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Stem Cell-Based Human Blood-Brain Barrier Models for Drug Discovery and Delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Induced pluripotent stem cell-derived myeloid phagocytes: disease modeling and therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

In Vitro T-Cell Generation From Adult, Embryonic, and Induced Pluripotent Stem Cells: Many Roads to One Destination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Modeling mouse and human development using organoid cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Cytosystems dynamics in self-organization of tissue architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

In vitro organogenesis from pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Engineering Stem Cell Organoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Current Public Support for Human-Animal Chimera Research in Japan Is Limited, Despite High Levels of Scientific Approval.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Identification of rare variants in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Induced pluripotent stem cells: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Does retroviral insertional mutagenesis play a role in the generation of induced pluripotent stem cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Human induced pluripotent stem cells free of vector and transgene sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

A more efficient method to generate integration-free human iPS cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Induced pluripotent stem cells generated without viral integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

A nonviral minicircle vector for deriving human iPS cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Reprogramming of mouse and human cells to pluripotency using mature microRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

RNA-programmed genome editing in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

High-Throughput Screening Using iPSC-Derived Neuronal Progenitors to Identify Compounds Counteracting Epigenetic Gene Silencing in Fragile X Syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

High-Throughput Screening to Identify Compounds That Increase Fragile X Mental Retardation Protein Expression in Neural Stem Cells Differentiated From Fragile X Syndrome Patient-Derived Induced Pluripotent Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

International SMA consortium meeting. (26-28 June 1992, Bonn, Germany)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

The Brazilian Zika virus strain causes birth defects in experimental models

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Stem-cell discovery platforms yield first clinical candidates

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Human embryonic stem cell-derived cardiac progenitors for severe heart failure treatment: first clinical case report: Figure 1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Immunogenicity of induced pluripotent stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Neural progenitor cells from human induced pluripotent stem cells generated less autogenous immune response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Establishment of Reporter Lines for Detecting Fragile X Mental Retardation (FMR1) Gene Reactivation in Human Neural Cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2016.245

Duplication of TBK1 Stimulates Autophagy in iPSC-derived Retinal Cells from a Patient with Normal Tension Glaucoma

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27980341

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27980341

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRD.2016.245

1 reference

30 June 2019

Dimensions Publication ID

0 references

1 reference

30 June 2019

PubMed ID

27980341

1 reference

30 June 2019