Paxillin phosphorylation by JNK and p38 is required for NFAT activation (Q39302141)

10 September 2017

title

Paxillin phosphorylation by JNK and p38 is required for NFAT activation (English)

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10 September 2017

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Yu-Chi Lee

1

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10 September 2017

An-Yun Chang

2

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10 September 2017

Ming-Hsien Lin-Feng

3

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10 September 2017

Wen-I Tsou

4

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10 September 2017

I-Hsuan Chiang

5

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10 September 2017

Ming-Zong Lai

6

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10 September 2017

language of work or name

English

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publication date

1 August 2012

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European Journal of Immunology

10 September 2017

published in

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10 September 2017

volume

42

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10 September 2017

issue

8

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10 September 2017

page(s)

2165-2175

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Paxillin and focal adhesion signalling

10 September 2017

cites work

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Paxillin comes of age

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Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells

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Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration

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Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis

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Hepatocyte growth factor induces ERK-dependent paxillin phosphorylation and regulates paxillin-focal adhesion kinase association

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JNK phosphorylates paxillin and regulates cell migration

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Phosphorylation of paxillin by p38MAPK is involved in the neurite extension of PC-12 cells

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Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis

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Glycogen synthase kinase 3- and extracellular signal-regulated kinase-dependent phosphorylation of paxillin regulates cytoskeletal rearrangement

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Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics

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JNK phosphorylation of paxillin, acting through the Rac1 and Cdc42 signaling cascade, mediates neurite extension in N1E-115 cells

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P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation.

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JNK-mediated phosphorylation of paxillin in adhesion assembly and tension-induced cell death by the adenovirus death factor E4orf4.

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An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation

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Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

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Paxillin binding to the alpha 4 integrin subunit stimulates LFA-1 (integrin alpha L beta 2)-dependent T cell migration by augmenting the activation of focal adhesion kinase/proline-rich tyrosine kinase-2.

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A small molecule that inhibits the interaction of paxillin and alpha 4 integrin inhibits accumulation of mononuclear leukocytes at a site of inflammation

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The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation

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JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin

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The beta1 integrin activates JNK independent of CagA, and JNK activation is required for Helicobacter pylori CagA+-induced motility of gastric cancer cells

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Molecular basis of calcium signaling in lymphocytes: STIM and ORAI

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Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

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NFAT signaling: choreographing the social lives of cells

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21 January 2018

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Nuclear factor of activated T cells c is a target of p38 mitogen-activated protein kinase in T cells

21 January 2018

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Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-kappaB transcription factors

21 January 2018

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Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoter

21 January 2018

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Interaction of the tau2 transcriptional activation domain of glucocorticoid receptor with a novel steroid receptor coactivator, Hic-5, which localizes to both focal adhesions and the nuclear matrix

21 January 2018

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Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling

21 January 2018

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Skin homing of Sézary cells involves SDF-1-CXCR4 signaling and down-regulation of CD26/dipeptidylpeptidase IV.

21 January 2018

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Phosphatidylinositide 3-Kinase Priming Couples c-FLIP to T Cell Activation

21 January 2018

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Serine phosphorylation of paxillin by heregulin-beta1: role of p38 mitogen activated protein kinase

21 January 2018

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7 January 2021

Phosphorylation of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201142192

7 January 2021

A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation

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https://api.crossref.org/works/10.1002%2FEJI.201142192

7 January 2021

Pervanadate-induced adhesion of CD4+ T cell to fibronectin is associated with tyrosine phosphorylation of paxillin.

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https://api.crossref.org/works/10.1002%2FEJI.201142192

7 January 2021

Deltex1 is a target of the transcription factor NFAT that promotes T cell anergy

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https://api.crossref.org/works/10.1002%2FEJI.201142192

7 January 2021

The tumor suppressor death-associated protein kinase targets to TCR-stimulated NF-kappa B activation

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https://api.crossref.org/works/10.1002%2FEJI.201142192

7 January 2021

Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice

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https://api.crossref.org/works/10.1002%2FEJI.201142192

7 January 2021

Identifiers

DOI

10.1002/EJI.201142192

1 reference

10 September 2017

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