GSK3-SCF(FBXW7) targets JunB for degradation in G2 to preserve chromatid cohesion before anaphase (Q39329020)

11 September 2017

GSK3-SCF(FBXW7) targets JunB for degradation in G2 to preserve chromatid cohesion before anaphase (English)

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11 September 2017

B Pérez-Benavente

1

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11 September 2017

J L García

2

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11 September 2017

M S Rodríguez

3

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11 September 2017

A Pineda-Lucena

4

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11 September 2017

M Piechaczyk

5

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11 September 2017

J Font de Mora

6

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11 September 2017

R Farràs

7

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11 September 2017

language of work or name

English

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publication date

18 June 2012

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11 September 2017

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11 September 2017

32

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11 September 2017

17

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11 September 2017

2189-2199

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https://scigraph.springernature.com/pub.10.1038/onc.2012.235

11 September 2017

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Sub-megabase resolution tiling (SMRT) array-based comparative genomic hybridization profiling reveals novel gains and losses of chromosomal regions in Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma cell lines

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Amplification at 7q22 targets cyclin-dependent kinase 6 in T-cell lymphoma

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Genomic profiling reveals different genetic aberrations in systemic ALK-positive and ALK-negative anaplastic large cell lymphomas.

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Genomic profiling of peripheral T-cell lymphoma, unspecified, and anaplastic large T-cell lymphoma delineates novel recurrent chromosomal alterations

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The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling

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AP-1 in cell proliferation and survival

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AP-1: a double-edged sword in tumorigenesis

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Emerging roles of ATF2 and the dynamic AP1 network in cancer

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Regulation and function of JunB in cell proliferation

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JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells.

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Gene expression profiling in chronic myeloid leukemia patients treated with hydroxyurea

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The transcriptome of the leukemogenic homeoprotein HOXA9 in human hematopoietic cells

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Transcription factors junB and c-jun are selectively up-regulated and functionally implicated in fibrosarcoma development

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Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation

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JunB can substitute for Jun in mouse development and cell proliferation

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Cell cycle-dependent variations in c-Jun and JunB phosphorylation: a role in the control of cyclin D1 expression.

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JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression

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Cell cycle promoting activity of JunB through cyclin A activation

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JunB breakdown in mid-/late G2 is required for down-regulation of cyclin A2 levels and proper mitosis

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Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.

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JunB expression is a common feature of CD30+ lymphomas and lymphomatoid papulosis

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Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.

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c-Jun NH2-terminal kinases target the ubiquitination of their associated transcription factors

21 January 2018

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Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

21 January 2018

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FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

21 January 2018

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The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

21 January 2018

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The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

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Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase

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SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.

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The akt kinase: molecular determinants of oncogenicity

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Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1

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Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.

21 January 2018

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The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells

21 January 2018

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Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma.

21 January 2018

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The jun and fos protein families are both required for cell cycle progression in fibroblasts

21 January 2018

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Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts

21 January 2018

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Inactivation of hCDC4 can cause chromosomal instability

21 January 2018

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FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation

21 January 2018

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Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

21 January 2018

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Warsaw breakage syndrome, a cohesinopathy associated with mutations in the XPD helicase family member DDX11/ChlR1

21 January 2018

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GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers.

21 January 2018

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The ubiquitous nature of cancer: the role of the SCF(Fbw7) complex in development and transformation

21 January 2018

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c-Fos Proto-Oncoprotein Is Degraded by the Proteasome Independently of Its Own Ubiquitinylation In Vivo

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.235

Chronic Myeloid Leukemia with Increased Granulocyte Progenitors in Mice Lacking JunB Expression in the Myeloid Lineage

21 January 2018

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Pathobiology of anaplastic large cell lymphoma

21 January 2018

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JunB induced by constitutive CD30-extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase signaling activates the CD30 promoter in anaplastic large cell lymphoma and reed-sternberg cells of Hodgkin lymphoma

31 March 2020

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Amplification and overexpression of JUNB is associated with primary cutaneous T-cell lymphomas

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2012.235

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Dimensions Publication ID

11 September 2017

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