TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation (Q39332938)

11 September 2017

TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation (English)

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11 September 2017

protein ubiquitination

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P-H Lin

1

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11 September 2017

W-M Lan

series ordinal

2

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11 September 2017

L-Y Chau

series ordinal

3

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11 September 2017

language of work or name

English

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publication date

11 June 2012

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11 September 2017

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11 September 2017

32

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18

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2325-2334

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https://scigraph.springernature.com/pub.10.1038/onc.2012.244

11 September 2017

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cites work

The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

A constitutional balanced t(3;8)(p14;q24.1) translocation results in disruption of the TRC8 gene and predisposition to clear cell renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

The tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Pharmacological and clinical aspects of heme oxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Heme oxygenase-1 in tumors: is it a false friend?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Identification of heme oxygenase-1 as a novel BCR/ABL-dependent survival factor in chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Overexpression of heme oxygenase-1 in murine melanoma: increased proliferation and viability of tumor cells, decreased survival of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Heme oxygenase-1 protects against apoptosis induced by tumor necrosis factor-alpha and cycloheximide in papillary thyroid carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Induction of heme-oxygenase 1 requires the p38MAPK and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Targeting of heat shock protein 32 (Hsp32)/heme oxygenase-1 (HO-1) in leukemic cells in chronic myeloid leukemia: a novel approach to overcome resistance against imatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Inhibition of heme oxygenase 1 expression by small interfering RNA decreases orthotopic tumor growth in livers of mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

A cis-acting region regulates oxidized lipid-mediated induction of the human heme oxygenase-1 gene in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Cadmium-responsive element of the human heme oxygenase-1 gene mediates heat shock factor 1-dependent transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Ubiquitin-proteasome system mediates heme oxygenase-1 degradation through endoplasmic reticulum-associated degradation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Oligomerization is crucial for the stability and function of heme oxygenase-1 in the endoplasmic reticulum

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.244

The ubiquitylation machinery of the endoplasmic reticulum

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.244

The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Haem oxygenase-1 plays a central role in NNK-mediated lung carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

CXCR3-B can mediate growth-inhibitory signals in human renal cancer cells by down-regulating the expression of heme oxygenase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

The heme oxygenase-1 protein is overexpressed in human renal cancer cells following activation of the Ras-Raf-ERK pathway and mediates anti-apoptotic signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Heme oxygenase-1 and carbon monoxide modulate DNA repair through ataxia-telangiectasia mutated (ATM) protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Cell context reveals a dual role for Maf in oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Sirtuin 1 in malignant transformation: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Transcriptome analysis of human cancer reveals a functional role of heme oxygenase-1 in tumor cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Transcriptional regulation of heme oxygenases by HIF-1alpha in renal medullary interstitial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Role of Bach1 and Nrf2 in up-regulation of the heme oxygenase-1 gene by cobalt protoporphyrin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

Overexpression of the heme oxygenase gene in renal cell carcinoma

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.244

T cell epitope definition by differential mass spectrometry: identification of a novel, immunogenic HLA-B8 ligand directly from renal cancer tissue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

A tumor suppressor and oncogene: the WT1 story.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.244

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.244

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11 September 2017

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