Pancreatic Beta Cell Identity in Humans and the Role of Type 2 Diabetes (Q39355916)

11 September 2017

1 reference

title

Pancreatic Beta Cell Identity in Humans and the Role of Type 2 Diabetes (English)

1 reference

11 September 2017

0 references

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28589121%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Lorella Marselli

5

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13 June 2020

author name string

Piero Marchetti

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13 June 2020

Vincenzo De Tata

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28589121%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Mara Suleiman

4

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13 June 2020

publication date

23 May 2017

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Frontiers in Cell and Developmental Biology

11 September 2017

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13 June 2020

volume

5

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13 June 2020

page(s)

55

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Heterogeneity of the Pancreatic Beta Cell

13 June 2020

cites work

1 reference

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11 September 2017

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Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.

11 September 2017

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RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes

11 September 2017

1 reference

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Pancreatic β-cell identity in diabetes.

11 September 2017

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11 September 2017

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Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes

11 September 2017

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11 September 2017

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Different downstream signalling of CCK1 receptors regulates distinct functions of CCK in pancreatic beta cells

11 September 2017

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Pancreatic β-cell identity, glucose sensing and the control of insulin secretion.

11 September 2017

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11 September 2017

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Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

11 September 2017

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Nutrient regulation of insulin secretion and action

11 September 2017

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Pancreas development in humans

11 September 2017

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The role of FOXO1 in β-cell failure and type 2 diabetes mellitus

11 September 2017

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Age-dependent labeling and imaging of insulin secretory granules

11 September 2017

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Inactivation of specific β cell transcription factors in type 2 diabetes

11 September 2017

1 reference

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Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction

11 September 2017

1 reference

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Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes

11 September 2017

1 reference

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Therapeutic potential of VIP vs PACAP in diabetes

11 September 2017

1 reference

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Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure

11 September 2017

1 reference

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A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets

11 September 2017

1 reference

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Evolving insights regarding mechanisms for the inhibition of insulin release by norepinephrine and heterotrimeric G proteins

11 September 2017

1 reference

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The dual control of insulin secretion by glucose involves triggering and amplifying pathways in β-cells

11 September 2017

1 reference

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Incretin physiology beyond glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: cholecystokinin and gastrin peptides

11 September 2017

1 reference

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Gene expression profiles of Beta-cell enriched tissue obtained by laser capture microdissection from subjects with type 2 diabetes

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

Microscopic anatomy of the human islet of Langerhans

11 September 2017

1 reference

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G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta-cell

11 September 2017

1 reference

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Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

Mitochondrial dysfunction in pancreatic beta-cells in Type 2 diabetes

11 September 2017

1 reference

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The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

11 September 2017

1 reference

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An overview of pancreatic beta-cell defects in human type 2 diabetes: implications for treatment.

11 September 2017

1 reference

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Mechanisms of action of glucagon-like peptide 1 in the pancreas

11 September 2017

1 reference

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The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

11 September 2017

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Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients

11 September 2017

1 reference

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Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

11 September 2017

1 reference

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Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes

11 September 2017

1 reference

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Stimulus-secretion coupling in the pancreatic beta-cell

11 September 2017

1 reference

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Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function

11 September 2017

1 reference

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neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

11 September 2017

1 reference

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Enzymatic, metabolic and secretory patterns in human islets of type 2 (non-insulin-dependent) diabetic patients

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

The insulin factory: a tour of the plant surroundings and a visit to the assembly line. The Minkowski lecture 1973 revisited

11 September 2017

1 reference

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Beta-cell development and turnover during prenatal life in humans

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

Glucagon physiology and pathophysiology in the light of new advances

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

Loss of β-Cell Identity Occurs in Type 2 Diabetes and Is Associated With Islet Amyloid Deposits

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia

25 September 2017

1 reference

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15 June 2018

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Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion

15 June 2018

1 reference

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Effects of secretin on the normal and pathological beta-cell

15 June 2018

1 reference

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Physiology: Pancreatic β-cell heterogeneity revisited.

15 June 2018

1 reference

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Acute metabolic amplification of insulin secretion in mouse islets is mediated by mitochondrial export of metabolites, but not by mitochondrial energy generation

21 August 2018

1 reference

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Autophagy in human type 2 diabetes pancreatic beta cells.

21 August 2018

1 reference

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Transcription factor expression in the developing human fetal endocrine pancreas.

21 August 2018

1 reference

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Global gene expression profiling and histochemical analysis of the developing human fetal pancreas

21 August 2018

1 reference

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Functional and molecular defects of pancreatic islets in human type 2 diabetes

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

The cytokine interleukin-1beta reduces the docking and fusion of insulin granules in pancreatic beta-cells, preferentially decreasing the first phase of exocytosis

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

Beta cell differentiation during early human pancreas development.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

Pulsatile insulin release from islets isolated from three subjects with type 2 diabetes

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440564

Regulation of Pancreatic Beta Cell Stimulus-Secretion Coupling by microRNAs.

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.3389%2FFCELL.2017.00055

Are we overestimating the loss of beta cells in type 2 diabetes?

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.3389%2FFCELL.2017.00055

Ultrastructural morphometric analysis of insulin secretory granules in human type 2 diabetes

21 January 2018

1 reference

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https://api.crossref.org/works/10.3389%2FFCELL.2017.00055

Immunohistochemical characterisation of cells co-producing insulin and glucagon in the developing human pancreas

21 January 2018

1 reference

12 December 2020

Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses

1 reference

12 December 2020

Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects

1 reference

12 December 2020

Electron microscopy of the islets of Langerhans

1 reference

12 December 2020

Identifiers

DOI

10.3389/FCELL.2017.00055

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28589121%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28589121%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference