Biphasic effects of transforming growth factor β on bone morphogenetic protein-induced osteoblast differentiation (Q39536713)

12 September 2017

title

Biphasic effects of transforming growth factor β on bone morphogenetic protein-induced osteoblast differentiation (English)

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12 September 2017

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David J J de Gorter

1

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12 September 2017

Maarten van Dinther

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2

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12 September 2017

Olexandr Korchynskyi

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3

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12 September 2017

Peter ten Dijke

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4

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publication date

1 June 2011

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Journal of Bone and Mineral Research

12 September 2017

published in

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12 September 2017

volume

26

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issue

6

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12 September 2017

page(s)

1178-1187

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Mechanisms of anabolic therapies for osteoporosis

12 September 2017

cites work

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Transforming growth factor-beta1 to the bone

21 January 2018

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TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation

21 January 2018

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Differential effects of transforming growth factor-beta on the synthesis of extracellular matrix proteins by normal fetal rat calvarial bone cell populations

21 January 2018

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TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation

21 January 2018

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Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells

21 January 2018

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Bone: formation by autoinduction

21 January 2018

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Novel regulators of bone formation: molecular clones and activities

21 January 2018

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Bone morphogenetic proteins

21 January 2018

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A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

21 January 2018

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Bone morphogenetic proteins in clinical applications

21 January 2018

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Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin

21 January 2018

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Bone morphogenetic proteins induce the expression of noggin, which limits their activity in cultured rat osteoblasts

21 January 2018

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Cloning and characterization of a human type II receptor for bone morphogenetic proteins

21 January 2018

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21 January 2018

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Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

21 January 2018

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Smad transcription factors

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Specificity and versatility in tgf-beta signaling through Smads

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

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Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter

21 January 2018

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Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation.

21 January 2018

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Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription.

21 January 2018

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Opposite effects of bone morphogenetic protein-2 and transforming growth factor-beta1 on osteoblast differentiation

21 January 2018

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Receptor Tyrosine Kinases Inhibit Bone Morphogenetic Protein‐Smad Responsive Promoter Activity and Differentiation of Murine MC3T3‐E1 Osteoblast‐like Cells

21 January 2018

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Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

21 January 2018

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Subcloning of three osteoblastic cell lines with distinct differentiation phenotypes from the mouse osteoblastic cell line KS-4.

21 January 2018

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BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

21 January 2018

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Differentiation of murine preosteoblastic KS483 cells depends on autocrine bone morphogenetic protein signaling during all phases of osteoblast formation

21 January 2018

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A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum

21 January 2018

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Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone

21 January 2018

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Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype

21 January 2018

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The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis

21 January 2018

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Induction of endochondral bone formation by recombinant human transforming growth factor-beta2 in the baboon (Papio ursinus).

21 January 2018

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Recombinant transforming growth factor-beta1 induces endochondral bone in the baboon and synergizes with recombinant osteogenic protein-1 (bone morphogenetic protein-7) to initiate rapid bone formation

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Loss of myostatin (GDF8) function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading.

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TAK1 is an essential regulator of BMP signalling in cartilage

21 January 2018

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The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

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21 January 2018

Identifiers

DOI

10.1002/JBMR.313

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12 September 2017

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