TAK1 is an essential regulator of BMP signalling in cartilage (Q28586793)

GOA release 2020-03-11

SMAD family member 1

1 reference

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

GOA release 2020-03-11

1 reference

7

Steven Gygi

1 reference

31 January 2017

2

Matthew B. Greenblatt

1 reference

31 January 2017

8

Laurie H. Glimcher

1 reference

31 January 2017

1

Jae-Hyuck Shim

1 reference

31 January 2017

Min Xie

3

1 reference

31 January 2017

Michael D. Schneider

series ordinal

4

1 reference

31 January 2017

Weiguo Zou

series ordinal

5

1 reference

31 January 2017

Bo Zhai

series ordinal

6

1 reference

31 January 2017

language of work or name

English

0 references

publication date

22 July 2009

1 reference

31 January 2017

1 reference

31 January 2017

28

1 reference

31 January 2017

14

1 reference

31 January 2017

2028–2041

1 reference

31 January 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Transforming growth factor-beta-activated kinase 1 is essential for differentiation and the prevention of apoptosis in epidermis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

The TGF beta activated kinase TAK1 regulates vascular development in vivo

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Hrs, a mammalian master molecule in vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal transducing adaptor molecule 1 and 2

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

TGF-beta signal transduction

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Novel regulators of bone formation: molecular clones and activities

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Developmental regulation of the growth plate

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Essential role of TAK1 in thymocyte development and activation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Transforming growth factor-beta-activated kinase-1 (TAK1), a MAP3K, interacts with Smad proteins and interferes with osteogenesis in murine mesenchymal progenitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

BMP signaling in skeletal development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Multiple functions of BMPs in chondrogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Id: a target of BMP signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Role of TAK1 and TAB1 in BMP signaling in early Xenopus development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

SMAD 8 binding to mice Msx1 basal promoter is required for transcriptional activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Primary culture and phenotyping of murine chondrocytes.

3 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.162

Developmental patterning in chondrocytic cultures by morphogenic gradients: BMP induces expression of indian hedgehog and noggin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.162

Essential function for the kinase TAK1 in innate and adaptive immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.162

TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.162

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.162

BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.162

Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699391

Smad4 is required for the normal organization of the cartilage growth plate

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19536134

12 December 2020

inferred from PubMed ID database lookup

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19536134

12 December 2020

inferred from PubMed ID database lookup

BMP signaling stimulates chondrocyte maturation and the expression of Indian hedgehog

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19536134

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/EMBOJ.2009.162

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xf2nukdsqfadxnjw5uaz33oqfa

30 July 2022

release_xf2nukdsqfadxnjw5uaz33oqfa

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xf2nukdsqfadxnjw5uaz33oqfa

30 July 2022

OpenCitations bibliographic resource ID

2463560

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://api.fatcat.wiki/v0/release/xf2nukdsqfadxnjw5uaz33oqfa

30 July 2022

https://api.fatcat.wiki/v0/release/xf2nukdsqfadxnjw5uaz33oqfa

1 reference

30 July 2022