Development of S/MAR minicircles for enhanced and persistent transgene expression in the mouse liver (Q39596256)

13 September 2017

title

Development of S/MAR minicircles for enhanced and persistent transgene expression in the mouse liver (English)

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13 September 2017

5

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13 September 2017

Orestis Argyros

1

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13 September 2017

Suet Ping Wong

2

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13 September 2017

Constantinos Fedonidis

3

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13 September 2017

Oleg Tolmachov

4

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13 September 2017

Steven J Howe

6

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13 September 2017

Marcello Niceta

7

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13 September 2017

Charles Coutelle

8

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13 September 2017

Richard P Harbottle

9

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13 September 2017

language of work or name

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8 February 2011

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Journal of Molecular Medicine

13 September 2017

published in

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13 September 2017

volume

89

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13 September 2017

issue

5

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13 September 2017

page(s)

515-529

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Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1alpha promoter.

13 September 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle

21 January 2018

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Long-term transgene expression from plasmid DNA gene therapy vectors is negatively affected by CpG dinucleotides

21 January 2018

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Histone modifications are associated with the persistence or silencing of vector-mediated transgene expression in vivo

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Challenges and strategies: the immune responses in gene therapy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Contribution of Toll-like receptor 9 signaling to the acute inflammatory response to nonviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Silencing of episomal transgene expression in liver by plasmid bacterial backbone DNA is independent of CpG methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Gene silencing in mammalian cells and the spread of DNA methylation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Molecular mechanisms of gene silencing mediated by DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo

21 January 2018

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Minicircle: an improved DNA molecule for in vitro and in vivo gene transfer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Minicircle performance depending on S/MAR-nuclear matrix interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Nuclear-targeted minicircle to enhance gene transfer with non-viral vectors in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Radioprotection in vitro and in vivo by minicircle plasmid carrying the human manganese superoxide dismutase transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Sustained transgene expression using MAR elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Correlations between scaffold/matrix attachment region (S/MAR) binding activity and DNA duplex destabilization energy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Stress-induced duplex DNA destabilization in scaffold/matrix attachment regions

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Designing nonviral vectors for efficient gene transfer and long-term gene expression

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

An episomally replicating vector binds to the nuclear matrix protein SAF-A in vivo

21 January 2018

1 reference

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A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Direct comparison of hepatocyte-specific expression cassettes following adenoviral and nonviral hydrodynamic gene transfer

21 January 2018

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Site-specific transgene integration in the human genome catalyzed by phiBT1 phage integrase

21 January 2018

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Inactive chromatin spreads from a focus of methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Performance of genomic bordering elements at predefined genomic loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

MAR elements regulate the probability of epigenetic switching between active and inactive gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Identification of the murine firefly luciferase-specific CD8 T-cell epitopes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Genetic immunization for antibody generation in research animals by intravenous delivery of plasmid DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Linear DNAs concatemerize in vivo and result in sustained transgene expression in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Non-viral S/MAR vectors replicate episomally in vivo when provided with a selective advantage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-010-0713-3

Transcriptional augmentation: modulation of gene expression by scaffold/matrix-attached regions (S/MAR elements).

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21301798

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CpG-depleted plasmid DNA vectors with enhanced safety and long-term gene expression in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21301798

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Strategies for the episomal modification of cells.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21301798

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00109-010-0713-3

1 reference

13 September 2017

1 reference