von Hippel-Lindau-dependent patterns of RNA polymerase II hydroxylation in human renal clear cell carcinomas (Q39639553)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978146%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

von Hippel-Lindau-dependent patterns of RNA polymerase II hydroxylation in human renal clear cell carcinomas (English)

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14 January 2020

8

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14 January 2020

Jarek Meller

9

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14 January 2020

author name string

Ying Yi

1

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14 January 2020

Olga Mikhaylova

2

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14 January 2020

Aygun Mamedova

3

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14 January 2020

Prabhat Bastola

4

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14 January 2020

Jacek Biesiada

5

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14 January 2020

Enas Alshaikh

6

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14 January 2020

Linda Levin

7

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14 January 2020

Maria F Czyzyk-Krzeska

10

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14 January 2020

language of work or name

English

0 references

publication date

26 October 2010

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14 January 2020

published in

Clinical Cancer Research

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14 January 2020

volume

16

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14 January 2020

issue

21

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14 January 2020

page(s)

5142-5152

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Absence of VHL gene alteration and high VEGF expression are associated with tumour aggressiveness and poor survival of renal-cell carcinoma

14 January 2020

cites work

1 reference

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Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

14 September 2017

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iTRAQ proteomic identification of pVHL-dependent and -independent targets of Egln1 prolyl hydroxylase knockdown in renal carcinoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970636

Intermittent hypoxia regulates RNA polymerase II in hippocampus and prefrontal cortex

14 September 2017

1 reference

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HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma

14 September 2017

1 reference

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Low CAIX expression and absence of VHL gene mutation are associated with tumor aggressiveness and poor survival of clear cell renal cell carcinoma

14 September 2017

1 reference

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The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress

14 September 2017

1 reference

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CDC25 phosphatases in cancer cells: key players? Good targets?

14 September 2017

1 reference

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Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity

14 September 2017

1 reference

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Hypoxia-induced assembly of prolyl hydroxylase PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2

14 September 2017

1 reference

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Prevalence of von Hippel-Lindau gene mutations in sporadic renal cell carcinoma: results from The Netherlands cohort study

14 September 2017

1 reference

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Decreased growth of Vhl-/- fibrosarcomas is associated with elevated levels of cyclin kinase inhibitors p21 and p27.

14 September 2017

1 reference

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von Hippel-Lindau tumor suppressor: not only HIF's executioner

14 September 2017

1 reference

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Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970636

von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970636

Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970636

Molecular basis of the VHL hereditary cancer syndrome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970636

Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970636

Prevalence, morphology and biology of renal cell carcinoma in von Hippel-Lindau disease compared to sporadic renal cell carcinoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970636

Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer.

25 September 2017

1 reference

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Loss of expression of von Hippel-Lindau tumor suppressor protein associated with improved survival in patients with early-stage clear cell renal cell carcinoma

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970636

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970636

VHL tumor suppressor gene alterations associated with good prognosis in sporadic clear-cell renal carcinoma

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20978146

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1078-0432.CCR-09-3416

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978146%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20978146%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference