c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription. (Q39676079)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11739718%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

title

c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription (English)

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4 December 2019

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Julian Aragones Lopez

4

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4 December 2019

author name string

Arántzazu Alfranca

1

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4 December 2019

M Dolores Gutiérrez

2

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4 December 2019

Alicia Vara

3

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4 December 2019

Felipe Vidal

5

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4 December 2019

Manuel O Landázuri

6

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4 December 2019

language of work or name

English

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publication date

1 January 2002

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Molecular and Cellular Biology

4 December 2019

published in

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4 December 2019

volume

22

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4 December 2019

issue

1

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4 December 2019

page(s)

12-22

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Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway.

4 December 2019

cites work

1 reference

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14 September 2017

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Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP.

14 September 2017

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Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells

14 September 2017

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

14 September 2017

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Loss of PTEN facilitates HIF-1-mediated gene expression

14 September 2017

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14 September 2017

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14 September 2017

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CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins

14 September 2017

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Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells

14 September 2017

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HIF1A gene transcription is dependent on a core promoter sequence encompassing activating and inhibiting sequences located upstream from the transcription initiation site and cis elements located within the 5'UTR

14 September 2017

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

14 September 2017

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Control of cell cycle progression by c-Jun is p53 dependent

14 September 2017

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Recruitment of the retinoblastoma protein to c-Jun enhances transcription activity mediated through the AP-1 binding site

14 September 2017

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c-Jun is a JNK-independent coactivator of the PU.1 transcription factor.

14 September 2017

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c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms

14 September 2017

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Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

14 September 2017

1 reference

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

14 September 2017

1 reference

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Steroid receptor coactivator-1 coactivates activating protein-1-mediated transactivations through interaction with the c-Jun and c-Fos subunits

14 September 2017

1 reference

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

14 September 2017

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Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun

14 September 2017

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Autocrine growth and anchorage independence: two complementing Jun-controlled genetic programs of cellular transformation.

14 September 2017

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

14 September 2017

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V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression.

14 September 2017

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Activator-protein-1 binding potentiates the hypoxia-induciblefactor-1-mediated hypoxia-induced transcriptional activation of vascular-endothelial growth factor expression in C6 glioma cells

14 September 2017

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

14 September 2017

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A cytoplasmic inhibitor of the JNK signal transduction pathway

14 September 2017

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A novel mechanism of JNK1 activation. Nuclear translocation and activation of JNK1 during ischemia and reperfusion

14 September 2017

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An essential role for p300/CBP in the cellular response to hypoxia

14 September 2017

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

14 September 2017

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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

14 September 2017

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The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site

14 September 2017

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Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.

14 September 2017

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Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor

14 September 2017

1 reference

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Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

14 September 2017

1 reference

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Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134229

Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134229

Regulation of c-jun expression during hypoxic and low-glucose stress

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134229

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134229

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

14 September 2017

1 reference

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Regulation of erythropoietin production. New insights into molecular mechanisms of oxygen homeostasis.

14 September 2017

1 reference

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Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134229

Rat embryo fibroblasts transformed by c-Jun display highly metastatic and angiogenic activities in vivo and deregulate gene expression of both angiogenic and antiangiogenic factors.

25 September 2017

1 reference

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Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha

25 September 2017

1 reference

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Oxygen- and dioxin-regulated gene expression in mouse hepatoma cells

25 September 2017

1 reference

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c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1.

25 September 2017

1 reference

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Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

15 June 2018

1 reference

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Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

15 June 2018

1 reference

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Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases

15 June 2018

1 reference

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Mechanism of action of a dominant-negative mutant of c-Jun.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134229

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=134229

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

21 August 2018

1 reference

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Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro

21 August 2018

1 reference

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Evidence for the involvement of diacylglycerol kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tension

2 December 2018

1 reference

12 December 2020

Hypoxia/reoxygenation stimulates Jun kinase activity through redox signaling in cardiac myocytes

1 reference

12 December 2020

Hypoxic Stimulation of the Stress-activated Protein Kinases in Pulmonary Artery Fibroblasts

1 reference

12 December 2020

Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal

1 reference

12 December 2020

Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific post-transcriptional regulation

1 reference

12 December 2020

Intersection of interferon and hypoxia signal transduction pathways in nitric oxide-induced tumor apoptosis

1 reference

12 December 2020

Hypoxic Regulation of Lactate Dehydrogenase A

1 reference

12 December 2020

Hypoxia-induced protein binding to O2-responsive sequences on the tyrosine hydroxylase gene

1 reference

12 December 2020

Hypoxia induces AP-1-regulated genes and AP-1 transcription factor binding in human endothelial and other cell types

1 reference

12 December 2020

10.1128/MCB.22.1.12-22.2002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11739718%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11739718%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

PubMed publication ID

11739718

1 reference