Inhibition of isoprenylcysteine carboxylmethyltransferase induces autophagic-dependent apoptosis and impairs tumor growth (Q39681605)

13 September 2017

Inhibition of isoprenylcysteine carboxylmethyltransferase induces autophagic-dependent apoptosis and impairs tumor growth (English)

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13 September 2017

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M Wang

1

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13 September 2017

M S Hossain

2

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13 September 2017

W Tan

3

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13 September 2017

B Coolman

4

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13 September 2017

J Zhou

5

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13 September 2017

S Liu

6

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13 September 2017

P J Casey

7

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13 September 2017

language of work or name

English

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publication date

12 July 2010

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13 September 2017

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13 September 2017

29

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13 September 2017

35

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13 September 2017

4959-4970

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https://scigraph.springernature.com/pub.10.1038/onc.2010.247

13 September 2017

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cites work

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The isoprenoid substrate specificity of isoprenylcysteine carboxylmethyltransferase: development of novel inhibitors

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31 March 2020

CaaX converting enzymes

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Time-dependent inhibition of isoprenylcysteine carboxyl methyltransferase by indole-based small molecules

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Programmed cell death (PCD). Apoptosis, autophagic PCD, or others?

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Absence of prohibitin gene mutations in human epithelial ovarian tumors

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

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Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum

31 March 2020

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Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to adriamycin

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NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy

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Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4.

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Therapeutic intervention based on protein prenylation and associated modifications

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Promotion of autophagy as a mechanism for radiation sensitization of breast tumor cells

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The Drosophila homolog of Aut1 is essential for autophagy and development.

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

31 March 2020

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LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

31 March 2020

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Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation

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Isoprenylcysteine carboxyl methyltransferase activity modulates endothelial cell apoptosis

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The role of autophagy during the early neonatal starvation period

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Autophagy in aging, disease and death: the true identity of a cell death impostor

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Fatty acylation and prenylation of proteins: what's hot in fat.

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Molecular mechanisms and regulation of specific and nonspecific autophagy pathways in yeast

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Apparent caspase independence of programmed cell death in Dictyostelium.

31 March 2020

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Developmental cell death in dictyostelium does not require paracaspase

31 March 2020

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Does autophagy have a license to kill mammalian cells?

31 March 2020

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31 March 2020

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Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death

31 March 2020

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Farnesyltransferase inhibitors: a detailed chemical view on an elusive biological problem

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Redistribution of U-snRNPs during mitosis

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Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.

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Inactivating Icmt ameliorates K-RAS-induced myeloproliferative disease.

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A small molecule inhibitor of isoprenylcysteine carboxymethyltransferase induces autophagic cell death in PC3 prostate cancer cells

31 March 2020

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K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

31 March 2020

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A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells.

31 March 2020

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Post-prenylation-processing enzymes as new targets in oncogenesis

31 March 2020

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Topology of mammalian isoprenylcysteine carboxyl methyltransferase determined in live cells with a fluorescent probe

31 March 2020

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.247

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.247

Protein prenylation: molecular mechanisms and functional consequences

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.247

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.247

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Dimensions Publication ID

13 September 2017

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