PKCeta confers protection against apoptosis by inhibiting the pro-apoptotic JNK activity in MCF-7 cells (Q39838678)

15 September 2017

PKCeta confers protection against apoptosis by inhibiting the pro-apoptotic JNK activity in MCF-7 cells (English)

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15 September 2017

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Noa Rotem-Dai

1

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15 September 2017

Galia Oberkovitz

series ordinal

2

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15 September 2017

Sara Abu-Ghanem

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3

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15 September 2017

Etta Livneh

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4

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15 September 2017

language of work or name

English

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publication date

10 June 2009

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Experimental Cell Research

15 September 2017

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15 September 2017

315

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15 September 2017

15

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15 September 2017

2616-2623

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15 September 2017

The Hallmarks of Cancer

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Ways of dying: multiple pathways to apoptosis.

7 January 2021

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Cell death: critical control points

7 January 2021

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Molecular mechanisms of caspase regulation during apoptosis

7 January 2021

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The pathophysiology of mitochondrial cell death

7 January 2021

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The Bcl-2 family: roles in cell survival and oncogenesis.

7 January 2021

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Serine/threonine protein kinases and apoptosis.

7 January 2021

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Role of Jun and Jun kinase in resistance of cancer cells to therapy

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

The isoform-specific regulation of apoptosis by protein kinase C.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Protein kinase C and lipid signaling for sustained cellular responses

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

The extended protein kinase C superfamily

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Protein kinase C modulation and anticancer drug response

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Protein kinase C mRNA levels and activity in reconstituted normal human epidermis: relationships to cell differentiation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Induction of differentiation in normal human keratinocytes by adenovirus-mediated introduction of the eta and delta isoforms of protein kinase C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Phorbol 12-myristate 13-acetate induces protein kinase ceta-specific proliferative response in astrocytic tumor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

PKCeta enhances cell cycle progression, the expression of G1 cyclins and p21 in MCF-7 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Linking protein kinase C to cell-cycle control

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

PKCeta associates with cyclin E/cdk2/p21 complex, phosphorylates p21 and inhibits cdk2 kinase in keratinocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

PKCη associates with cyclin E/Cdk2 complex in serum-starved MCF-7 and NIH-3T3 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Overexpression of protein kinase C-eta attenuates caspase activation and tumor necrosis factor-alpha-induced cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Protein kinase C-eta regulates resistance to UV- and gamma-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

The eta isoform of protein kinase C inhibits UV-induced activation of caspase-3 in normal human keratinocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

PKCeta expression contributes to the resistance of Hodgkin's lymphoma cell lines to apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Multiple gene expression analysis reveals distinct differences between G2 and G3 stage breast cancers, and correlations of PKC eta with MDR1, MRP and LRP gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Down-regulation of protein kinase Ceta by antisense oligonucleotides sensitises A549 lung cancer cells to vincristine and paclitaxel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

The molecular control of DNA damage-induced cell death

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Homocamptothecins: potent topoisomerase I inhibitors and promising anticancer drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Apoptotic signaling cascades.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Multiple pathways of cytochrome c release from mitochondria in apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Mitochondria and apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Fos family members induce cell cycle entry by activating cyclin D1.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Caspases: intracellular signaling by proteolysis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

RACK1 mediates activation of JNK by protein kinase C [corrected].

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

PKC delta mediates ionizing radiation-induced activation of c-Jun NH(2)-terminal kinase through MKK7 in human thyroid cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Activation of SAPK/JNK signaling by protein kinase Cdelta in response to DNA damage

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Protein kinase D signaling

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Protein kinase C phosphorylates protein kinase D activation loop Ser744 and Ser748 and releases autoinhibition by the pleckstrin homology domain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

PKCeta is localized in the Golgi, ER and nuclear envelope and translocates to the nuclear envelope upon PMA activation and serum-starvation: C1b domain and the pseudosubstrate containing fragment target PKCeta to the Golgi and the nuclear envelope

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Protein kinase C (PKC)eta-mediated PKC mu activation modulates ERK and JNK signal pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Protein kinase D complexes with C-Jun N-terminal kinase via activation loop phosphorylation and phosphorylates the C-Jun N-terminus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Identification of a novel phosphorylation site in c-jun directly targeted in vitro by protein kinase D.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Protein kinase C eta upregulation and secretion during postnatal rat mammary gland differentiation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Hormonal regulation of PKC: estrogen up-regulates PKCeta expression in estrogen-responsive breast cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

Altered expression and localization of PKC eta in human breast tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

PKC eta as a therapeutic target in glioblastoma multiforme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.004

10.1016/J.YEXCR.2009.06.004

7 January 2021

Identifiers

DOI

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15 September 2017

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