Full-length hdmX transcripts decrease following genotoxic stress (Q39949523)

15 September 2017

Full-length hdmX transcripts decrease following genotoxic stress (English)

1 reference

15 September 2017

1 reference

M Markey

1

1 reference

PMCID

2610866

15 September 2017

S J Berberich

series ordinal

2

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PMCID

2610866

15 September 2017

language of work or name

English

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publication date

18 August 2008

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15 September 2017

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15 September 2017

27

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15 September 2017

6657-6666

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15 September 2017

52

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https://scigraph.springernature.com/pub.10.1038/onc.2008.266

15 September 2017

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p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

22 September 2017

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A microRNA component of the p53 tumour suppressor network

22 September 2017

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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

22 September 2017

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Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

22 September 2017

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22 September 2017

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Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

22 September 2017

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MDMX regulation of p53 response to ribosomal stress

22 September 2017

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Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4.

22 September 2017

1 reference

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Regulation of hdm2 by stress-induced hdm2alt1 in tumor and nontumorigenic cell lines correlating with p53 stability

22 September 2017

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"Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells".

22 September 2017

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14-3-3gamma binds to MDMX that is phosphorylated by UV-activated Chk1, resulting in p53 activation

22 September 2017

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Mdmx as an essential regulator of p53 activity

22 September 2017

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22 September 2017

Human MicroRNA targets

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Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity

22 September 2017

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Decision making by p53: life, death and cancer

22 September 2017

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22 September 2017

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Tumor suppression by Ink4a-Arf: progress and puzzles

22 September 2017

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DNA damage induces MDMX nuclear translocation by p53-dependent and -independent mechanisms

22 September 2017

1 reference

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Live or let die: the cell's response to p53

22 September 2017

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22 September 2017

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Mutual dependence of MDM2 and MDMX in their functional inactivation of p53

22 September 2017

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MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts

22 September 2017

1 reference

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Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

22 September 2017

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Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

22 September 2017

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22 September 2017

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Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

22 September 2017

1 reference

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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

22 September 2017

1 reference

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MDMX: a novel p53-binding protein with some functional properties of MDM2

22 September 2017

1 reference

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Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

22 September 2017

1 reference

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

22 September 2017

1 reference

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Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

22 September 2017

1 reference

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Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

22 September 2017

1 reference

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610866

Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610866

Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610866

Hdmx protein stability is regulated by the ubiquitin ligase activity of Mdm2.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610866

Constitutive mdmx expression during cell growth, differentiation, and DNA damage

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610866

Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610866

Significance of HDMX-S (or MDM4) mRNA splice variant overexpression and HDMX gene amplification on primary soft tissue sarcoma prognosis.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610866

Comparative study of the p53-mdm2 and p53-MDMX interfaces

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2008.266

A novel form of Epstein-Barr virus latency in normal B cells in vivo

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2008.266

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.266

1 reference

15 September 2017

1 reference

15 September 2017

1 reference

PMCID

2610866