Pre-folding IkappaBalpha alters control of NF-kappaB signaling (Q39977321)

16 September 2017

Pre-folding IkappaBalpha alters control of NF-kappaB signaling (English)

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16 September 2017

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Stephanie M E Truhlar

1

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16 September 2017

Erika Mathes

2

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16 September 2017

Carla F Cervantes

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16 September 2017

Gourisankar Ghosh

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16 September 2017

Elizabeth A Komives

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16 September 2017

language of work or name

English

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publication date

4 March 2008

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Journal of Molecular Biology

16 September 2017

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380

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1

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67-82

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describes a project that uses

16 September 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2519148/fullTextXML

inferred from PubMed Central ID database lookup

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22 September 2017

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Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution.

22 September 2017

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Nuclear factor-kappaB: its role in health and disease

22 September 2017

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The ankyrin repeat as molecular architecture for protein recognition

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Designed to be stable: crystal structure of a consensus ankyrin repeat protein

22 September 2017

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Endoproteolytic activity of the proteasome

22 September 2017

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Consensus-derived structural determinants of the ankyrin repeat motif

22 September 2017

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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

22 September 2017

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22 September 2017

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Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators

22 September 2017

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22 September 2017

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The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

22 September 2017

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Structure of an IkappaBalpha/NF-kappaB complex

22 September 2017

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Ikappa Balpha functions through direct contacts with the nuclear localization signals and the DNA binding sequences of NF-kappaB

22 September 2017

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22 September 2017

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22 September 2017

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The signal response of IkappaB alpha is regulated by transferable N- and C-terminal domains

22 September 2017

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Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

22 September 2017

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The NF-kappa B and I kappa B proteins: new discoveries and insights

22 September 2017

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Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

22 September 2017

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22 September 2017

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Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

22 September 2017

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In vivo control of NF-kappa B activation by I kappa B alpha.

22 September 2017

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NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

22 September 2017

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A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

22 September 2017

1 reference

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

22 September 2017

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Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

22 September 2017

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Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

22 September 2017

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22 September 2017

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I kappa B: a specific inhibitor of the NF-kappa B transcription factor

22 September 2017

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22 September 2017

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22 September 2017

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Cytokine-inducible expression in endothelial cells of an I kappa B alpha-like gene is regulated by NF kappa B.

22 September 2017

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Different mechanisms control signal-induced degradation and basal turnover of the NF-kappaB inhibitor IkappaB alpha in vivo

25 September 2017

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UV as an amplifier rather than inducer of NF-kappaB activity

25 September 2017

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A homeostatic model of IkappaB metabolism to control constitutive NF-kappaB activity

17 June 2018

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Stabilizing IkappaBalpha by "consensus" design

17 June 2018

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Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity.

17 June 2018

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Mechanism of direct degradation of IkappaBalpha by 20S proteasome

17 June 2018

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The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

17 June 2018

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The role of protein dynamics in increasing binding affinity for an engineered protein-protein interaction established by H/D exchange mass spectrometry.

17 June 2018

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Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex.

20 August 2018

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The energy landscape of modular repeat proteins: topology determines folding mechanism in the ankyrin family

20 August 2018

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The tolerance of a modular protein to duplication and deletion of internal repeats

20 August 2018

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The LEF-1 high-mobility group domain undergoes a disorder-to-order transition upon formation of a complex with cognate DNA.

20 August 2018

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20 August 2018

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Structure-based substitutions for increased solubility of a designed protein

20 August 2018

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Appearance of apparently ubiquitin-conjugated I kappa B-alpha during its phosphorylation-induced degradation in intact cells

20 August 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/18511071

12 December 2020

inferred from PubMed ID database lookup

Stability and folding of the tumour suppressor protein p16

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PubMed

https://pubmed.ncbi.nlm.nih.gov/18511071

12 December 2020

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The structural stability of a protein is an important determinant of its proteolytic susceptibility in Escherichia coli

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PubMed

https://pubmed.ncbi.nlm.nih.gov/18511071

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.JMB.2008.02.053

1 reference

16 September 2017

1 reference

16 September 2017

PubMed publication ID

18511071

1 reference