Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli (Q39985730)

16 September 2017

title

Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli (English)

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16 September 2017

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A P Kouzmenko

1

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16 September 2017

K Takeyama

2

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16 September 2017

Y Kawasaki

3

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16 September 2017

T Akiyama

4

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16 September 2017

S Kato

5

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16 September 2017

language of work or name

English

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publication date

5 May 2008

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16 September 2017

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16 September 2017

volume

27

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16 September 2017

issue

36

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16 September 2017

page(s)

4888-4899

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APC-mediated downregulation of beta-catenin activity involves nuclear sequestration and nuclear export

16 September 2017

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Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion.

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Loss of adenomatous polyposis coli gene function disrupts thymic development

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Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC

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Dimer formation by an N-terminal coiled coil in the APC protein

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A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.

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Asef, a link between the tumor suppressor APC and G-protein signaling

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Tumor-associated NH2-terminal fragments are the most stable part of the adenomatous polyposis coli protein and can be regulated by interactions with COOH-terminal domains.

31 March 2020

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Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

31 March 2020

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Id2 gene-targeted crosstalk between Wnt and retinoid signaling regulates proliferation in human keratinocytes

31 March 2020

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The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells

31 March 2020

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31 March 2020

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Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction

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APC mutations occur early during colorectal tumorigenesis

31 March 2020

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The APC tumour suppressor has a nuclear export function.

31 March 2020

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Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner

31 March 2020

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31 March 2020

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The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes

31 March 2020

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31 March 2020

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Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas

31 March 2020

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Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability.

31 March 2020

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The histone code at DNA breaks: a guide to repair?

31 March 2020

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A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling

31 March 2020

1 reference

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Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway

31 March 2020

1 reference

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RETRACTED: Nuclear Receptor Function Requires a TFTC-Type Histone Acetyl Transferase Complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

Cell density and phosphorylation control the subcellular localization of adenomatous polyposis coli protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.127

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.127

1 reference

16 September 2017

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