Functional blockade of Smad4 leads to a decrease in beta-catenin levels and signaling activity in human pancreatic carcinoma cells (Q40007539)

16 September 2017

Functional blockade of Smad4 leads to a decrease in beta-catenin levels and signaling activity in human pancreatic carcinoma cells (English)

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16 September 2017

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Diana Romero

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16 September 2017

Maite Iglesias

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2

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16 September 2017

Calvin P H Vary

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3

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16 September 2017

Miguel Quintanilla

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4

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16 September 2017

language of work or name

English

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publication date

28 February 2008

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16 September 2017

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16 September 2017

29

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5

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16 September 2017

1070-1076

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TGFbeta signaling in growth control, cancer, and heritable disorders

16 September 2017

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

TGF-beta signaling in tumor suppression and cancer progression

21 January 2018

1 reference

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TGF-beta signaling: positive and negative effects on tumorigenesis

21 January 2018

1 reference

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TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

21 January 2018

1 reference

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Transforming growth factor beta 1 induces squamous carcinoma cell variants with increased metastatic abilities and a disorganized cytoskeleton

21 January 2018

1 reference

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You Wnt some, you lose some: oncogenes in the Wnt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Wnt signaling in the intestinal epithelium: from endoderm to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

beta-catenin is a target for the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

The oncogenic activation of beta-catenin

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Non-Smad TGF-beta signals

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Lessons from hereditary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Excess beta-catenin promotes accumulation of transcriptionally active p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Nuclear localization of EGF receptor and its potential new role as a transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

TGFbeta1 represses proliferation of pancreatic carcinoma cells which correlates with Smad4-independent inhibition of ERK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Epithelial-mesenchymal transitions in tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

TGF-beta modulates beta-Catenin stability and signaling in mesenchymal proliferations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

GLUT4 expression in 3T3-L1 adipocytes is repressed by proteasome inhibition, but not by inhibition of calpains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Role of Ras and Mapks in TGFbeta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Blockade of Smad4 in transformed keratinocytes containing a Ras oncogene leads to hyperactivation of the Ras-dependent Erk signalling pathway associated with progression to undifferentiated carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreatoblastomas : frequent alterations in the APC/beta-catenin pathway and chromosome 11p

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: frequent allelic loss on chromosome 11p and alterations in the APC/beta-catenin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Smad4 and β-Catenin Co-activators Functionally Interact with Lymphoid-enhancing Factor to Regulate Graded Expression of Msx2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Smad1, beta-catenin and Tcf4 associate in a molecular complex with the Myc promoter in dysplastic renal tissue and cooperate to control Myc transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN054

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGN054

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16 September 2017

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