HtrA2 enhances the apoptotic functions of p73 on bax. (Q40015300)

16 September 2017

HtrA2 enhances the apoptotic functions of p73 on bax. (English)

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16 September 2017

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M Marabese

1

1 reference

16 September 2017

M Mazzoletti

series ordinal

2

1 reference

16 September 2017

F Vikhanskaya

series ordinal

3

1 reference

16 September 2017

M Broggini

series ordinal

4

1 reference

16 September 2017

8 February 2008

1 reference

Cell Death & Differentiation

16 September 2017

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16 September 2017

15

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16 September 2017

5

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16 September 2017

849-858

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https://scigraph.springernature.com/pub.10.1038/cdd.2008.7

16 September 2017

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p73: Friend or foe in tumorigenesis

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p73 is a simian [correction of human] p53-related protein that can induce apoptosis

21 January 2018

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Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

21 January 2018

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p73 and p63 protein stability: the way to regulate function?

21 January 2018

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Autoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoter

21 January 2018

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DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors

21 January 2018

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DN-p73 is activated after DNA damage in a p53-dependent manner to regulate p53-induced cell cycle arrest.

21 January 2018

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Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53.

21 January 2018

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Two new p73 splice variants, gamma and delta, with different transcriptional activity.

21 January 2018

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Transdominant DeltaTAp73 isoforms are frequently up-regulated in ovarian cancer. Evidence for their role as epigenetic p53 inhibitors in vivo.

21 January 2018

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DeltaNp73 stabilises TAp73 proteins but compromises their function due to inhibitory hetero-oligomer formation

21 January 2018

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Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

1 reference

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2008.7

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

21 January 2018

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CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals.

21 January 2018

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Serine protease Omi/HtrA2 targets WARTS kinase to control cell proliferation.

21 January 2018

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p73: a chiaroscuro gene in cancer.

21 January 2018

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Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis

21 January 2018

1 reference

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Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death

21 January 2018

1 reference

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Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15

21 January 2018

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DNA damage induces transcriptional activation of p73 by removing C-EBP repression on E2F1

21 January 2018

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Increased DeltaN-p73 expression in tumors by upregulation of the E2F1-regulated, TA-promoter-derived DeltaN'-p73 transcript

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/CDD.2008.7

1 reference

Dimensions Publication ID

16 September 2017

0 references

1 reference