Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations. (Q40127751)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526729%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations (English)

1 reference

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31 December 2019

0 references

1 reference

4

1 reference

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31 December 2019

Yoji Andrew Minamishima

5

1 reference

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31 December 2019

author name string

Lianjie Li

1

1 reference

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31 December 2019

Liang Zhang

2

1 reference

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31 December 2019

Xiaoping Zhang

3

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31 December 2019

Aria F Olumi

6

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31 December 2019

Mao Mao

7

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31 December 2019

Steven Bartz

8

1 reference

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31 December 2019

William G Kaelin

9

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31 December 2019

language of work or name

English

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publication date

25 May 2007

1 reference

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Molecular and Cellular Biology

31 December 2019

published in

1 reference

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31 December 2019

volume

27

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31 December 2019

issue

15

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31 December 2019

page(s)

5381-5392

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VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail

31 December 2019

cites work

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VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

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The von Hippel-Lindau tumor suppressor gene and kidney cancer

22 September 2017

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Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

22 September 2017

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von Hippel-Lindau tumor suppressor: not only HIF's executioner

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Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors

22 September 2017

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Oxygen sensing by HIF hydroxylases

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The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen

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Hypoxia inducible factor activates the transforming growth factor-alpha/epidermal growth factor receptor growth stimulatory pathway in VHL(-/-) renal cell carcinoma cells

22 September 2017

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Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL.

22 September 2017

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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

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22 September 2017

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22 September 2017

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22 September 2017

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von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF.

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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VHL induces renal cell differentiation and growth arrest through integration of cell-cell and cell-extracellular matrix signaling

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2

22 September 2017

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22 September 2017

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22 September 2017

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Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene

22 September 2017

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Identification of intragenic mutations in the von Hippel-Lindau disease tumour suppressor gene and correlation with disease phenotype

22 September 2017

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Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C

22 September 2017

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Inhibition of transcription elongation by the VHL tumor suppressor protein

22 September 2017

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Characterization of the VHL tumor suppressor gene product: localization, complex formation, and the effect of natural inactivating mutations

22 September 2017

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22 September 2017

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25 September 2017

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Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene

25 September 2017

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In vivo selection of human renal cell carcinoma cells with high metastatic potential in nude mice

15 June 2018

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15 June 2018

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20 August 2018

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20 August 2018

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Renal cell carcinoma risk in type 2 von Hippel-Lindau disease correlates with defects in pVHL stability and HIF-1alpha interactions.

20 August 2018

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Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

20 August 2018

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HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron

20 August 2018

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The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma

20 August 2018

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Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

20 August 2018

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Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: correlations with phenotype

20 August 2018

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Orthotopic implantation is essential for the selection, growth and metastasis of human renal cell cancer in nude mice [corrected]

20 August 2018

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12 December 2020

Development of a high metastatic orthotopic model of human renal cell carcinoma in nude mice: benefits of fragment implantation compared to cell-suspension injection

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12 December 2020

Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer

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12 December 2020

Cellular proteins that bind the von Hippel-Lindau disease gene product: mapping of binding domains and the effect of missense mutations

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12 December 2020

Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene

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12 December 2020

Identifiers

DOI

10.1128/MCB.00282-07

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526729%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526729%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference