Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. (Q33863055)

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13 January 2020

title

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma (English)

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13 January 2020

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3

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13 January 2020

Chris Pugh

7

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13 January 2020

Adrian Harris

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13 January 2020

Peter J. Ratcliffe

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13 January 2020

author name string

Raju R Raval

1

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13 January 2020

Kah Weng Lau

2

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13 January 2020

Heidi M Sowter

4

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13 January 2020

Stefano J Mandriota

5

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13 January 2020

Ji-Liang Li

6

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13 January 2020

Patrick H Maxwell

8

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13 January 2020

language of work or name

English

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publication date

1 July 2005

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Molecular and Cellular Biology

13 January 2020

published in

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13 January 2020

volume

25

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13 January 2020

page(s)

5675-5686

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13 January 2020

issue

13

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Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

13 January 2020

cites work

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The von Hippel-Lindau Gene, Kidney Cancer, and Oxygen Sensing

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5 July 2018

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Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha

5 July 2018

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Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy

5 July 2018

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Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.

5 July 2018

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Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

5 July 2018

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VHL-mediated hypoxia regulation of cyclin D1 in renal carcinoma cells.

5 July 2018

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Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

5 July 2018

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Hypoxia--a key regulatory factor in tumour growth

5 July 2018

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5 July 2018

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5 July 2018

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Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function

5 July 2018

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5 July 2018

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Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through hypoxia-inducible factor.

5 July 2018

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Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.

29 October 2018

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HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron

29 October 2018

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The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma

29 October 2018

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Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

29 October 2018

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Suppression of tumor growth through disruption of hypoxia-inducible transcription

29 October 2018

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10.1128/MCB.25.13.5675-5686.2005

29 October 2018

Identifiers

DOI

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13 January 2020

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13 January 2020

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