Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression. (Q40214713)

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scientific article published on 28 September 2006

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English	Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression.	scientific article published on 28 September 2006

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scholarly article

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21 December 2019

Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression (English)

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21 December 2019

sodium arsenite

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ChEBI release 2020-05-28

Vladimir N Ivanov

1

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21 December 2019

author name string

Tom K Hei

2

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28 September 2006

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21 December 2019

Experimental Cell Research

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21 December 2019

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21 December 2019

4120-4138

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21 December 2019

cFLIP regulation of lymphocyte activation and development

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22 September 2017

Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells

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The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

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TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt.

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A phase II trial of arsenic trioxide in patients with metastatic melanoma

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Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis.

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Inhibition of CaMKII-mediated c-FLIP expression sensitizes malignant melanoma cells to TRAIL-induced apoptosis.

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22 September 2017

Combined treatment with EGFR inhibitors and arsenite upregulated apoptosis in human EGFR-positive melanomas: a role of suppression of the PI3K-AKT pathway

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22 September 2017

Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity.

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Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis.

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Recent advances in melanoma biology

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Arsenite sensitizes human melanomas to apoptosis via tumor necrosis factor alpha-mediated pathway

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Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells

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22 September 2017

Arsenic trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL.

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An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis

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The paradox of arsenic: molecular mechanisms of cell transformation and chemotherapeutic effects

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How melanoma cells evade trail-induced apoptosis.

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NF-kappaB at the crossroads of life and death

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Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling.

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FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

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NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

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22 September 2017

Arsenite stimulates plasma membrane NADPH oxidase in vascular endothelial cells

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22 September 2017

Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells

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ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis.

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The role of NF-kappa B in TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of melanoma cells

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Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells

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Identifiers

10.1016/J.YEXCR.2006.09.019

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Europe PubMed Central

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21 December 2019

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21 December 2019

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21 December 2019

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