Hexamethylene amiloride blocks E protein ion channels and inhibits coronavirus replication (Q40260580)

19 September 2017

Hexamethylene amiloride blocks E protein ion channels and inhibits coronavirus replication (English)

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19 September 2017

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Lauren Wilson

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19 September 2017

Peter Gage

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2

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19 September 2017

Gary Ewart

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3

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19 September 2017

language of work or name

English

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publication date

3 July 2006

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19 September 2017

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19 September 2017

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19 September 2017

294-306

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19 September 2017

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Coronavirus pseudoparticles formed with recombinant M and E proteins induce alpha interferon synthesis by leukocytes.

19 September 2017

2 references

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

7 January 2021

12 December 2020

Infectious bronchitis virus E protein is targeted to the Golgi complex and directs release of virus-like particles

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Amiloride derivatives block ion channel activity and enhancement of virus-like particle budding caused by HIV-1 protein Vpu.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Potential new anti-human immunodeficiency virus type 1 compounds depress virus replication in cultured human macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Viral ion channels: structure and function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Analysis of constructed E gene mutants of mouse hepatitis virus confirms a pivotal role for E protein in coronavirus assembly

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

7 January 2021

12 December 2020

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

1 reference

A comparative sequence analysis to revise the current taxonomy of the family Coronaviridae.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

7 January 2021

12 December 2020

Scrambling of the amino acids within the transmembrane domain of Vpu results in a simian-human immunodeficiency virus (SHIVTM) that is less pathogenic for pig-tailed macaques.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

The small envelope protein E is not essential for murine coronavirus replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Chemically unambiguous peptide immunogen: Preparation, orientation and antigenicity of purified peptide conjugated to the multiple antigen peptide system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Viroporin activity of murine hepatitis virus E protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Membrane topology of coronavirus E protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Alphavirus 6K proteins form ion channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Generation of a replication-competent, propagation-deficient virus vector based on the transmissible gastroenteritis coronavirus genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Influenza virus M2 protein has ion channel activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Cation-selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Dengue virus M protein C-terminal peptide (DVM-C) forms ion channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

The ion channel activity of the influenza virus M2 protein affects transport through the Golgi apparatus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Structural characteristics of the M2 protein of influenza A viruses: evidence that it forms a tetrameric channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

SARS coronavirus E protein forms cation-selective ion channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2006.05.028

Managing influenza: amantadine, rimantadine and beyond

7 January 2021

1 reference

12 December 2020

Small envelope protein E of SARS: cloning, expression, purification, CD determination, and bioinformatics analysis.

1 reference

12 December 2020

The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains.

1 reference

12 December 2020

The Vpu protein of human immunodeficiency virus type 1 forms cation-selective ion channels

1 reference

12 December 2020

Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques

1 reference

12 December 2020

10.1016/J.VIROL.2006.05.028

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DOI

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19 September 2017

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