Identification of novel Runx1 (AML1) translocation partner genes SH3D19, YTHDf2, and ZNF687 in acute myeloid leukemia (Q40305071)

19 September 2017

title

Identification of novel Runx1 (AML1) translocation partner genes SH3D19, YTHDf2, and ZNF687 in acute myeloid leukemia (English)

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19 September 2017

TuDung T Nguyen

1

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19 September 2017

Lisa N Ma

2

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19 September 2017

Marilyn L Slovak

3

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19 September 2017

Charles D Bangs

4

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19 September 2017

Athena M Cherry

5

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19 September 2017

Daniel A Arber

6

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19 September 2017

publication date

1 October 2006

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Genes, Chromosomes and Cancer

19 September 2017

published in

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19 September 2017

volume

45

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19 September 2017

issue

10

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19 September 2017

page(s)

918-932

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Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML

19 September 2017

cites work

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7 January 2021

AML1-FOG2 fusion protein in myelodysplasia

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7 January 2021

Chromosomal translocation mechanisms at intronic alu elements in mammalian cells

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7 January 2021

Chromosome 21 tandem repetition and AML1 (RUNX1) gene amplification.

1 reference

7 January 2021

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

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7 January 2021

Alu repeat analysis in the complete human genome: trends and variations with respect to genomic composition

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7 January 2021

Multiple modes of RNA recognition by zinc finger proteins

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7 January 2021

Molecular characterization of the genomic breakpoints in a case of t(3;21)(q26;q22)

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7 January 2021

Fusion AML1 transcript in a radiation-associated leukemia results in a truncated inhibitory AML1 protein

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7 January 2021

Molecular basis of tissue-specific gene expression mediated by the runt domain transcription factor PEBP2/CBF.

1 reference

7 January 2021

Oncogenic potential of the RUNX gene family: 'overview'.

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7 January 2021

Nonrandom distribution of interspersed repeat elements in the BCR and ABL1 genes and its relation to breakpoint cluster regions

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7 January 2021

Repbase Update, a database of eukaryotic repetitive elements

1 reference

7 January 2021

An investigation of the t(12;21) rearrangement in children with B-precursor acute lymphoblastic leukaemia using cytogenetic and molecular methods

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7 January 2021

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

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7 January 2021

Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis

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7 January 2021

The role of Alu repeat clusters as mediators of recurrent chromosomal aberrations in tumors

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7 January 2021

Role of AML1/Runx1 in the pathogenesis of hematological malignancies

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7 January 2021

Initial sequencing and analysis of the human genome

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7 January 2021

Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1

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7 January 2021

AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML.

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7 January 2021

Oncogenic transcription factors in the human acute leukemias

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7 January 2021

Changes in the DNA methylation profile of the rat H19 gene upstream region during development and transgenic hepatocarcinogenesis and its role in the imprinted transcriptional regulation of the H19 gene

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7 January 2021

Panhandle PCR for cDNA: a rapid method for isolation of MLL fusion transcripts involving unknown partner genes

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7 January 2021

AML1 interconnected pathways of leukemogenesis

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7 January 2021

A novel gene, FGA7, is fused to RUNX1/AML1 in a t(4;21)(q28;q22) in a patient with T-cell acute lymphoblastic leukemia

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7 January 2021

AML1 gene over-expression in childhood acute lymphoblastic leukemia

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7 January 2021

Alternative splicing and genomic structure of theAML1gene involved in acute myeloid leukemia

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7 January 2021

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

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7 January 2021

Runx1 is expressed in adult mouse hematopoietic stem cells and differentiating myeloid and lymphoid cells, but not in maturing erythroid cells

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7 January 2021

Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations

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7 January 2021

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

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7 January 2021

Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia

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7 January 2021

Designer zinc-finger proteins and their applications

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7 January 2021

A novel and cytogenetically cryptic t(7;21)(p22;q22) in acute myeloid leukemia results in fusion of RUNX1 with the ubiquitin-specific protease gene USP42.

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7 January 2021

AML1 deletion in adult mice causes splenomegaly and lymphomas.

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7 January 2021

Forced expression of AML1-AMP19, a fusion transcript generated from a radiation-associated t(19;21) leukemia, blocks myeloid differentiation

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7 January 2021

Fusion of AML1/Runx1 to copine VIII, a novel member of the copine family, in an aggressive acute myelogenous leukemia with t(12;21) translocation

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7 January 2021

Identification of two new translocations that disrupt the AML1 gene

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7 January 2021

Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome

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7 January 2021

Co-existence of multiple subclones in TEL-AML1 at diagnosis of acute lymphoblastic leukaemia in association with submicroscopic deletion of AML1.

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7 January 2021

A sex chromosome rearrangement in a human XX male caused by Alu-Alu recombination

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7 January 2021

Novel RUNX1-PRDM16 fusion transcripts in a patient with acute myeloid leukemia showing t(1;21)(p36;q22)

1 reference

7 January 2021

21q22 balanced chromosome aberrations in therapy-related hematopoietic disorders: report from an international workshop

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7 January 2021

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

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7 January 2021

Amplification of band q22 of chromosome 21, including AML1, in older children with acute lymphoblastic leukemia: an emerging molecular cytogenetic subgroup

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7 January 2021

Core-binding factors in haematopoiesis and leukaemia

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7 January 2021

Somatic point mutations in RUNX1/CBFA2/AML1 are common in high-risk myelodysplastic syndrome, but not in myelofibrosis with myeloid metaplasia

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7 January 2021

The partial tandem duplication of ALL1 (MLL) is consistently generated by Alu-mediated homologous recombination in acute myeloid leukemia

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7 January 2021

ADAM binding protein Eve-1 is required for ectodomain shedding of epidermal growth factor receptor ligands

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7 January 2021

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

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7 January 2021

The endocytic protein intersectin is a major binding partner for the Ras exchange factor mSos1 in rat brain

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7 January 2021

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

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7 January 2021

Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein

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7 January 2021

Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia

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7 January 2021

The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties.

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7 January 2021

PRDX4, a member of the peroxiredoxin family, is fused to AML1 (RUNX1) in an acute myeloid leukemia patient with a t(X;21)(p22;q22).

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7 January 2021

Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.

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7 January 2021

Progressive de novo DNA methylation at the bcr-abl locus in the course of chronic myelogenous leukemia

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7 January 2021

Identifiers

DOI

10.1002/GCC.20355

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19 September 2017

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