Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice. (Q40369825)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27094951%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice (English)

1 reference

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2 April 2020

1 reference

1 reference

8

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2 April 2020

Patrick Lévy

5

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2 April 2020

Jean Louis Pépin

7

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2 April 2020

Bruno Guigas

9

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2 April 2020

Judith Aron-Wisnewsky

3

object named as

Judith Aron-Wisnewsky

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2 April 2020

2

Elise Belaidi

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2 April 2020

4

Gerard C van der Zon

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2 April 2020

author name string

Amandine Thomas

1

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2 April 2020

Karine Clement

6

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2 April 2020

language of work or name

English

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publication date

20 April 2016

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2 April 2020

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2 April 2020

volume

6

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2 April 2020

page(s)

24618

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Creative Commons Attribution 4.0 International

2 April 2020

copyright license

start time

20 April 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/srep24618

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cites work

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Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes

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Selective inhibition of hypoxia-inducible factor 1α ameliorates adipose tissue dysfunction.

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Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice

22 September 2017

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Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation

22 September 2017

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Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation

22 September 2017

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Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis

22 September 2017

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Hypoxia-inducible factor 2 regulates hepatic lipid metabolism

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Hypoxia decreases insulin signaling pathways in adipocytes

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Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice

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Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.

22 September 2017

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Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo

22 September 2017

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Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity

22 September 2017

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

22 September 2017

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Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

22 September 2017

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22 September 2017

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

22 September 2017

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

22 September 2017

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22 September 2017

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Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system.

22 September 2017

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Uncoupling hypoxia signaling from oxygen sensing in the liver results in hypoketotic hypoglycemic death.

25 September 2017

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Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

15 June 2018

1 reference

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Prolyl hydroxylase domain protein 2 plays a critical role in diet-induced obesity and glucose intolerance

15 June 2018

1 reference

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Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837354

Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.

20 August 2018

1 reference

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Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice

20 August 2018

1 reference

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HIF Prolyl 4-Hydroxylase-2 Inhibition Improves Glucose and Lipid Metabolism and Protects Against Obesity and Metabolic Dysfunction

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27094951

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12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP24618

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27094951%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27094951%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference