A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects (Q40375946)

20 September 2017

A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects (English)

1 reference

20 September 2017

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Julia Spanier

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Ulrich Kalinke

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Mariola Fotin-Mleczek

13

object named as

Mariola Fotin-Mleczek

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

12

Karl-Josef Kallen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

9

Regina Heidenreich

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Claudia Soldner

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Stefan Lienenklaus

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Stephanie Trittel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Peggy Riese

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Thomas Kramps

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Siegfried Weiss

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Edith Jasny

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Carlos A Guzmán

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

11 January 2017

1 reference

20 September 2017

Journal of Immunology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

198

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

1595-1605

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

Comparison of the safety and immunogenicity of hepatitis B virus surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide and a licensed hepatitis B vaccine in healthy young adults

9 June 2020

cites work

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Towards an understanding of the adjuvant action of aluminium

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Alum adjuvant: some of the tricks of the oldest adjuvant

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Control of adaptive immunity by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Enhanced humoral and memory B cellular immunity using HPV16/18 L1 VLP vaccine formulated with the MPL/aluminium salt combination (AS04) compared to aluminium salt only

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: implications for vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Approaching the RNA ligand for RIG-I?

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

5'-Triphosphate RNA is the ligand for RIG-I

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

The combination of early and rapid type I IFN, IL-1α, and IL-1β production are essential mediators of RNA-like adjuvant driven CD4+ Th1 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Toll-like receptor-dependent activation of several human blood cell types by protamine-condensed mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

A novel, disruptive vaccination technology: self-adjuvanted RNActive(®) vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Functional role of type I and type II interferons in antiviral defense

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Modified vaccinia virus Ankara induces Toll-like receptor-independent type I interferon responses

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Interferon-beta is required for interferon-alpha production in mouse fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Novel reporter mouse reveals constitutive and inflammatory expression of IFN-beta in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

A transient three-plasmid expression system for the production of high titer retroviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Vesicular stomatitis virus glycoprotein displaying retrovirus-like particles induce a type I IFN receptor-dependent switch to neutralizing IgG antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

A novel RNA-based adjuvant combines strong immunostimulatory capacities with a favorable safety profile

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

The role of antibody concentration and avidity in antiviral protection.

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Vaccine adjuvants: putting innate immunity to work

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Psychological side effects of immune therapies: symptoms and pathomechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

The interferons: 50 years after their discovery, there is much more to learn

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Cytokine, sickness behavior, and depression

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Proinflammatory cytokine responses correspond with subjective side effects after influenza virus vaccination.

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

RIG-I-like receptors: cytoplasmic sensors for non-self RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

IFN-α as a vaccine adjuvant: recent insights into the mechanisms and perspectives for its clinical use.

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Programming the magnitude and persistence of antibody responses with innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Combination adjuvants: the next generation of adjuvants?

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

AS04, an aluminum salt- and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Vaccines: correlates of vaccine-induced immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

How do adjuvants work? Important considerations for new generation adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

In interleukin-4-deficient mice, alum not only generates T helper 1 responses equivalent to Freund's complete adjuvant, but continues to induce T helper 2 cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1601129

21 January 2018

Identifiers

DOI

10.4049/JIMMUNOL.1601129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28077601%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference