Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL. (Q40394610)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

main subject

hepatocellular carcinoma

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

author name string

Tom M Ganten

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Ronald Koschny

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Jaromir Sykora

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Min Li-Weber

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Kerstin Herzer

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Henning Walczak

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

language of work or name

English

0 references

publication date

1 September 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

volume

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

page(s)

588-597

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16037944%20AND%20SRC:MED&resulttype=core&format=json

The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems

31 December 2019

cites work

1 reference

7 January 2021

Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

1 reference

7 January 2021

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

1 reference

7 January 2021

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

1 reference

7 January 2021

CD95's deadly mission in the immune system

1 reference

7 January 2021

Biochemistry and function of the DISC

1 reference

7 January 2021

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

7 January 2021

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

1 reference

7 January 2021

Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.

1 reference

7 January 2021

c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

1 reference

7 January 2021

Proteasome inhibition as a novel therapeutic target in human cancer.

1 reference

7 January 2021

Deadly encounter: ubiquitin meets apoptosis

1 reference

7 January 2021

1 reference

7 January 2021

Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation

1 reference

7 January 2021

Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappaB

1 reference

7 January 2021

Primary human hepatocytes--a valuable tool for investigation of apoptosis and hepatitis B virus infection

1 reference

7 January 2021

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

7 January 2021

Use of a membrane-localized green fluorescent protein allows simultaneous identification of transfected cells and cell cycle analysis by flow cytometry

1 reference

7 January 2021

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

1 reference

7 January 2021

Involvement of Jun and Rel proteins in up-regulation of interleukin-4 gene activity by the T cell accessory molecule CD28.

1 reference

7 January 2021

RNA interference-mediated silencing of the S100A10 gene attenuates plasmin generation and invasiveness of Colo 222 colorectal cancer cells.

1 reference

7 January 2021

TRAIL and NFkappaB signaling--a complex relationship

1 reference

7 January 2021

Regulation of apoptosis proteins in cancer cells by ubiquitin

1 reference

7 January 2021

Inhibition of NF-kappaB activity enhances TRAIL mediated apoptosis in breast cancer cell lines.

1 reference

7 January 2021

The flip side of FLIP

1 reference

7 January 2021

The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells

1 reference

7 January 2021

Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies

1 reference

7 January 2021

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

1 reference

7 January 2021

The role of c-FLIP in modulation of CD95-induced apoptosis

1 reference

7 January 2021

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

1 reference

7 January 2021

Activation of caspases-8 and -10 by FLIP(L).

1 reference

7 January 2021

Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth

1 reference

7 January 2021