TRAIL and NFkappaB signaling--a complex relationship (Q35756866)

10 August 2017

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title

TRAIL and NFkappaB signaling--a complex relationship (English)

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10 August 2017

Harald Wajant

1

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10 August 2017

publication date

1 January 2004

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10 August 2017

published in

Vitamins and Hormones

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10 August 2017

volume

67

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10 August 2017

page(s)

101-132

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Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy

10 August 2017

cites work

1 reference

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7 January 2021

A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

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7 January 2021

Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

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7 January 2021

Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB

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7 January 2021

p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB

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7 January 2021

Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression

1 reference

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7 January 2021

Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha

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7 January 2021

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.

1 reference

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7 January 2021

Phosphorylation of IkappaB-alpha inhibits its cleavage by caspase CPP32 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

A unified model for apical caspase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Structural basis of caspase-7 inhibition by XIAP

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Interdimer processing mechanism of procaspase-8 activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Activation of the NF-kappaB pathway by caspase 8 and its homologs

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Activation of initiator caspases through a stable dimeric intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

CD40 regulates the processing of NF-kappaB2 p100 to p52

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Nuclear IkappaBbeta maintains persistent NF-kappaB activation in HIV-1-infected myeloid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Characterization of the human FLICE-inhibitory protein locus and comparison of the anti-apoptotic activity of four different flip isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Insights into the regulatory mechanism for caspase-8 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

KSHV vFLIP binds to IKK-gamma to activate IKK.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Caspase-9 processing by caspase-3 via a feedback amplification loop in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Regulation of RelA subcellular localization by a putative nuclear export signal and p50.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Autoamplification of apoptosis following ligation of CD95-L, TRAIL and TNF-α

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The generation of nfkb2 p52: mechanism and efficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Activation of NF-kappaB by FADD, Casper, and caspase-8.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Postrepression activation of NF-kappaB requires the amino-terminal nuclear export signal specific to IkappaBalpha

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Downregulation of c-FLIP sensitizes DU145 prostate cancer cells to Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Structure of an IkappaBalpha/NF-kappaB complex

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

NF-kappaB at the crossroads of life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Signaling and transcriptional control of Fas ligand gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

IRAK-M is a negative regulator of Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Molecular cross-talk between the TRAIL and interferon signaling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Apo2L/TRAIL and its death and decoy receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

TRAIL induces apoptosis and inflammatory gene expression in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

IKK1-deficient mice exhibit abnormal development of skin and skeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

NF-kappaB regulation in the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the Ikappa B kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

NF-kappaB signals induce the expression of c-FLIP.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

p105.Ikappa Bgamma and prototypical Ikappa Bs use a similar mechanism to bind but a different mechanism to regulate the subcellular localization of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Defining the dynamics of self-assembled Fas-receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

A critical role for the RelA subunit of nuclear factor kappaB in regulation of multiple immune-response genes and in Fas-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The triterpenoid CDDO induces apoptosis in refractory CLL B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The precursor of NF-kappa B p50 has I kappa B-like functions

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Structural basis for the inhibition of caspase-3 by XIAP

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

NF-kappaB signaling pathway governs TRAIL gene expression and human T-cell leukemia virus-I Tax-induced T-cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Nuclear import of IkappaBalpha is accomplished by a ran-independent transport pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Nuclear localization of IkappaB alpha is mediated by the second ankyrin repeat: the IkappaB alpha ankyrin repeats define a novel class of cis-acting nuclear import sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Direct phosphorylation of NF-kappaB1 p105 by the IkappaB kinase complex on serine 927 is essential for signal-induced p105 proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

IAP proteins: blocking the road to death's door

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and TNF-alpha promote the NF-kappaB-dependent maturation of normal and leukemic myeloid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFkappaB activation in epithelial derived cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Apoptosome: the cellular engine for the activation of caspase-9.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Tumor necrosis factor (TNF) and phorbol ester induce TNF-related apoptosis-inducing ligand (TRAIL) under critical involvement of NF-kappa B essential modulator (NEMO)/IKKgamma

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Role of unphosphorylated, newly synthesized I kappa B beta in persistent activation of NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Limb and skin abnormalities in mice lacking IKKalpha

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

IkappaB family members function by different mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Inhibition of JNK activation through NF-kappaB target genes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Regulation of lymphocyte proliferation and death by FLIP.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Mammalian mitochondrial IAP binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Endogenous membrane tumor necrosis factor (TNF) is a potent amplifier of TNF receptor 1-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Resistance of human ovarian cancer cells to tumor necrosis factor alpha is a consequence of nuclear factor kappaB-mediated induction of Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory protein

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Nuclear factor-kappa B-inducible death effector domain-containing protein suppresses tumor necrosis factor-mediated apoptosis by inhibiting caspase-8 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967007-5

7 January 2021

10.1016/S0083-6729(04)67007-5

Identifiers

DOI

1 reference

10 August 2017

1 reference