Functional interactions of antiapoptotic proteins and tumor necrosis factor in the context of a replication-competent adenovirus. (Q40416354)

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12 January 2020

title

Functional interactions of antiapoptotic proteins and tumor necrosis factor in the context of a replication-competent adenovirus (English)

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12 January 2020

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1

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12 January 2020

author name string

Wang Y

2

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12 January 2020

Hallden G

3

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12 January 2020

Brooks G

4

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12 January 2020

Francis J

5

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12 January 2020

Lemoine NR

6

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12 January 2020

Kirn D

7

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12 January 2020

publication date

1 September 2005

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12 January 2020

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12 January 2020

volume

12

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12 January 2020

issue

17

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12 January 2020

page(s)

1333-1346

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Replication-selective virotherapy for cancer: Biological principles, risk management and future directions

12 January 2020

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An E1B-19 kDa gene deletion mutant adenovirus demonstrates tumor necrosis factor-enhanced cancer selectivity and enhanced oncolytic potency

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An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

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A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

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Deletion of the adenoviral E1b-19kD gene enhances tumor cell killing of a replicating adenoviral vector

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Novel immunocompetent murine tumor models for the assessment of replication-competent oncolytic adenovirus efficacy.

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Infection of Mouse Liver by Human Adenovirus Type 5

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The dual effect of adenovirus type 5 E1A 13S protein on NF-kappaB activation is antagonized by E1B 19K.

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Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice

21 January 2018

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Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

21 January 2018

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Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

21 January 2018

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TNFalpha and IFNgamma induced by innate anti-adenoviral immune responses inhibit adenovirus-mediated transgene expression

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7 January 2021

The adenovirus E3 10.4K and 14.5K proteins, which function to prevent cytolysis by tumor necrosis factor and to down-regulate the epidermal growth factor receptor, are localized in the plasma membrane

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7 January 2021

An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

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Wild-type adenovirus decreases tumor xenograft growth, but despite viral persistence complete tumor responses are rarely achieved--deletion of the viral E1b-19-kD gene increases the viral oncolytic effect

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7 January 2021

Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302555

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15920462%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 January 2020

1000809284

0 references

1 reference