Notch1 oncoprotein antagonizes TGF-beta/Smad-mediated cell growth suppression via sequestration of coactivator p300. (Q40420353)

20 September 2017

title

Notch1 oncoprotein antagonizes TGF-beta/Smad-mediated cell growth suppression via sequestration of coactivator p300. (English)

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20 September 2017

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Shigeo Masuda

1

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20 September 2017

Keiki Kumano

2

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20 September 2017

Kiyoshi Shimizu

3

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20 September 2017

Yoichi Imai

4

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20 September 2017

Mineo Kurokawa

5

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20 September 2017

Seishi Ogawa

6

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20 September 2017

Makoto Miyagishi

7

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20 September 2017

Kazunari Taira

8

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20 September 2017

Hisamaru Hirai

9

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20 September 2017

Shigeru Chiba

10

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20 September 2017

publication date

1 May 2005

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20 September 2017

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20 September 2017

volume

96

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20 September 2017

issue

5

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20 September 2017

page(s)

274-282

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Notch signaling: cell fate control and signal integration in development

20 September 2017

cites work

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Deficient T cell fate specification in mice with an induced inactivation of Notch1.

21 January 2018

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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

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Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

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Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2.

21 January 2018

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The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4).

21 January 2018

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Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

21 January 2018

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Neoplastic transformation by Notch requires nuclear localization

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Notch signaling in leukemia

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

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A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer

21 January 2018

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Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.

21 January 2018

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p300 acts as a transcriptional coactivator for mammalian Notch-1

21 January 2018

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Role of p300, a transcriptional coactivator, in signalling of TGF-beta

21 January 2018

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TGFbeta signaling in growth control, cancer, and heritable disorders

21 January 2018

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TGF-beta signaling in tumor suppression and cancer progression

21 January 2018

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TGF-beta signaling: positive and negative effects on tumorigenesis

21 January 2018

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

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Genetic analysis of the mammalian transforming growth factor-beta superfamily

21 January 2018

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21 January 2018

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How cells read TGF-beta signals

21 January 2018

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The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3

21 January 2018

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Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis

21 January 2018

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Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression

21 January 2018

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Functional diversity among Notch1, Notch2, and Notch3 receptors

21 January 2018

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TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3

21 January 2018

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Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2

21 January 2018

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The intracellular form of notch blocks transforming growth factor beta-mediated growth arrest in Mv1Lu epithelial cells

21 January 2018

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Enhanced gene activation by Notch and BMP signaling cross-talk

21 January 2018

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Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells.

21 January 2018

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Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

21 January 2018

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Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

21 January 2018

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A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

21 January 2018

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Functional interplay between p53 and E2F through co-activator p300.

21 January 2018

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Transcriptional cross talk between NF-kappaB and p53.

21 January 2018

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Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1.

21 January 2018

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Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300.

21 January 2018

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Anchoring notch genetics and biochemistry; structural analysis of the ankyrin domain sheds light on existing data

21 January 2018

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Gamma-secretase: proteasome of the membrane?

21 January 2018

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Growth suppression of human carcinoma cells by reintroduction of the p300 coactivator

21 January 2018

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Mutations truncating the EP300 acetylase in human cancers

21 January 2018

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10.1111/J.1349-7006.2005.00048.X

21 January 2018

Identifiers

DOI

1 reference

20 September 2017

1 reference