Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4. (Q40473935)

20 September 2017

title

Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4. (English)

1 reference

20 September 2017

Che-Chang Chang

1

1 reference

20 September 2017

Ding-Yen Lin

2

1 reference

20 September 2017

Hsin-I Fang

3

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20 September 2017

Ruey-Hwa Chen

4

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20 September 2017

Hsiu-Ming Shih

5

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20 September 2017

language of work or name

English

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publication date

6 January 2005

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Journal of Biological Chemistry

20 September 2017

published in

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20 September 2017

volume

280

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20 September 2017

issue

11

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20 September 2017

page(s)

10164-10173

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Nuclear and unclear functions of SUMO

20 September 2017

cites work

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SUMO promotes HDAC-mediated transcriptional repression

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SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

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21 January 2018

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Activation of transforming growth factor-beta signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4

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Sumoylation of Smad4, the Common Smad Mediator of Transforming Growth Factor-β Family Signaling

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Repression of Smad4 transcriptional activity by SUMO modification

21 January 2018

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Daxx, a novel Fas-binding protein that activates JNK and apoptosis

21 January 2018

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TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

21 January 2018

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Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity

21 January 2018

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EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes

21 January 2018

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The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx

21 January 2018

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Regulation of Pax3 transcriptional activity by SUMO-1-modified PML

21 January 2018

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Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestration

21 January 2018

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Promyelocytic leukemia protein (PML) functions as a glucocorticoid receptor co-activator by sequestering Daxx to the PML oncogenic domains (PODs) to enhance its transactivation potential

21 January 2018

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Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PML

21 January 2018

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DAXX, FLASH, and FAF-1 modulate mineralocorticoid and glucocorticoid receptor-mediated transcription in hippocampal cells--toward a basis for the opposite actions elicited by two nuclear receptors?

21 January 2018

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Smad4 and β-Catenin Co-activators Functionally Interact with Lymphoid-enhancing Factor to Regulate Graded Expression of Msx2

21 January 2018

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TGF beta signals through a heteromeric protein kinase receptor complex

21 January 2018

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Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein

21 January 2018

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The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

21 January 2018

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Human Smad3 and Smad4 are sequence-specific transcription activators

21 January 2018

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Ligand-independent activation of transforming growth factor (TGF) beta signaling pathways by heteromeric cytoplasmic domains of TGF-beta receptors

21 January 2018

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Interaction of Daxx, a Fas binding protein, with sentrin and Ubc9

21 January 2018

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Negative modulation of androgen receptor transcriptional activity by Daxx

21 January 2018

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PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1

21 January 2018

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Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).

21 January 2018

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Sequestration and inhibition of Daxx-mediated transcriptional repression by PML

21 January 2018

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Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm

21 January 2018

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Role of the ASK1-SEK1-JNK1-HIPK1 signal in Daxx trafficking and ASK1 oligomerization.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409161200

Catalase, but not MnSOD, inhibits glucose deprivation-activated ASK1-MEK-MAPK signal transduction pathway and prevents relocalization of Daxx: hydrogen peroxide as a major second messenger of metabolic oxidative stress.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409161200

Post-translational modification by the small ubiquitin-related modifier SUMO has big effects on transcription factor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409161200

Transforming Growth Factor-β-mediated Signaling via the p38 MAP Kinase Pathway Activates Smad-dependent Transcription through SUMO-1 Modification of Smad4

21 January 2018

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TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409161200

The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409161200

Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409161200

Smad-Dependent Recruitment of a Histone Deacetylase/Sin3A Complex Modulates the Bone Morphogenetic Protein-Dependent Transcriptional Repressor Activity of Nkx3.2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409161200

Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409161200

Repression of Smad transcriptional activity by PIASy, an inhibitor of activated STAT.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409161200

Modification of Daxx by small ubiquitin-related modifier-1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M409161200

The adenovirus protein Gam1 interferes with sumoylation of histone deacetylase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409161200

SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409161200

PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409161200

PML and the oncogenic nuclear domains in regulating transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409161200

The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409161200

A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409161200

Heterochromatin and ND10 are cell-cycle regulated and phosphorylation-dependent alternate nuclear sites of the transcription repressor Daxx and SWI/SNF protein ATRX

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409161200

Characterization of functional domains within Smad4/DPC4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409161200

The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409161200

SMIF, a Smad4-interacting protein that functions as a co-activator in TGFbeta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409161200

p300 Transcriptional Repression Is Mediated by SUMO Modification

21 January 2018

1 reference

2 April 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/S1097-2765(03)00141-2

Identifiers

DOI

10.1074/JBC.M409161200

1 reference

20 September 2017

1 reference