Genetic and epigenetic alterations of the APC gene in malignant melanoma (Q40557851)

21 September 2017

title

Genetic and epigenetic alterations of the APC gene in malignant melanoma (English)

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21 September 2017

3

Kirsten Grønbaek

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author name string

Jesper Worm

1

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21 September 2017

Claus Christensen

2

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21 September 2017

Kirsten Grønbaek

3

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21 September 2017

Eugene Tulchinsky

4

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21 September 2017

Per Guldberg

5

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21 September 2017

language of work or name

English

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publication date

1 July 2004

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21 September 2017

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21 September 2017

volume

23

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21 September 2017

issue

30

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21 September 2017

page(s)

5215-5226

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A system for stable expression of short interfering RNAs in mammalian cells

21 September 2017

cites work

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Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity

21 January 2018

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Evidence that silencing of the HPRT promoter by DNA methylation is mediated by critical CpG sites

21 January 2018

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21 January 2018

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The APC gene in colorectal cancer

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APC, signal transduction and genetic instability in colorectal cancer

21 January 2018

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Somatic mutations of the APC gene in primary breast cancers

21 January 2018

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Identification of c-MYC as a target of the APC pathway

21 January 2018

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Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma.

21 January 2018

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The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase

21 January 2018

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Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

21 January 2018

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Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma

21 January 2018

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Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

21 January 2018

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

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Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling

21 January 2018

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The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells

21 January 2018

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Abnormalities of the APC/beta-catenin pathway in endometrial cancer

21 January 2018

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Cytoplasmic and nuclear accumulation of beta-catenin is rarely caused by CTNNB1 exon 3 mutations in cutaneous malignant melanoma

21 January 2018

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Molecular genetic analysis of malignant melanomas for aberrations of the WNT signaling pathway genes CTNNB1, APC, ICAT and BTRC.

21 January 2018

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Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma

21 January 2018

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Stabilization of beta-catenin by genetic defects in melanoma cell lines

21 January 2018

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

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Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia

21 January 2018

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Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells

21 January 2018

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Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors

21 January 2018

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Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation

21 January 2018

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The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phase

21 January 2018

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7 January 2021

Double-gradient DGGE for optimized detection of DNA point mutations

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7 January 2021

Loss of membranous expression of beta-catenin is associated with tumor progression in cutaneous melanoma and rarely caused by exon 3 mutations

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7 January 2021

The multiple functions of tumour suppressors: it's all in APC

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7 January 2021

Computational simulation of DNA melting and its application to denaturing gradient gel electrophoresis

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7 January 2021

Mutations in exon 3 of the β-catenin gene are rare in melanoma cell lines

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207647

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Dimensions Publication ID

21 September 2017

1020374172

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